Synthesis and biological evaluation of 14-alkoxymorphinans. 20.1 14-Phenylpropoxymetopon: An extremely powerful analgesic

Journal of Medicinal Chemistry

Volumn 46, Issue 19, 2003, Pages 4182-4187

  Schütz, Johannes ^a   Spetea, Mariana ^a,b   Hoch, Martin ^a   Aceto, Mario D ^c   Harris, Louis S ^c   Coop, Andrew ^d   Schmidhammer, Helmut ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BENZOQUINONE; 14 PHENYLPROPOXYMETOPON; ANALGESIC AGENT; DIHYDROETORPHINE; ETORPHINE; MORPHINAN DERIVATIVE; N METHYL 14 PHENYLPROPOXYMORPHINAN; UNCLASSIFIED DRUG;

ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; GASTROINTESTINAL MOTILITY; HOT PLATE TEST; LABELING INDEX; SYNTHESIS; TAIL FLICK TEST; WRITHING TEST;

ANALGESICS, OPIOID; ANIMALS; ETORPHINE; GUINEA PIGS; MALE; MICE; MICE, INBRED ICR; MORPHINANS; MORPHINE; MORPHOLINES; NOCICEPTORS; PAIN MEASUREMENT; RADIOLIGAND ASSAY; RATS; REACTION TIME; RECEPTORS, OPIOID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141678817     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030878b     Document Type: Article

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