Synthesis of novel apio carbocyclic nucleoside analogues as selective A3 adenosine receptor agonists

Journal of Organic Chemistry

Volumn 70, Issue 13, 2005, Pages 5006-5013

  Lee, Jeong A ^a   Moon, Hyung Ryong ^b   Kim, Hea Ok ^a   Kim, Kyung Ran ^b   Lee, Kang Man ^a   Kim, Bum Tae ^c   Hwang, Ki Jun ^c   Chun, Moon Woo ^d   Jacobson, Kenneth A ^e   Jeong, Lak Shin ^a  

^a Ewha Womans University   (South Korea)

^b Pusan National University   (South Korea)

^c Chonbuk National University   (South Korea)

^d Seoul National University   (South Korea)

^e NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSTS; FORMALDEHYDE; HYDROGENATION; OXIDATION; POTASSIUM COMPOUNDS; STEREOCHEMISTRY;

BINDING SITES; NUCLEOSIDES;

ORGANIC COMPOUNDS;

2 AMINO 9 [4,5 DIHYDROXY 4 HYDROXYMETHYLCYCLOPENT 2 ENYL] 1,9 DIHYDROPURIN 6 ONE; 2 HYDROXYMETHYL 5 (6 METHYLAMINOPURIN 9 YL)CYCLOPENT 3 ENE 1,2 DIOL; 2',3' DIDEOXYADENOSINE; 2,2 DIMETHYL 6 VINYLTETRAHYDROFURO[3,4 D][1,3]DIOXOL 4 OL; 3 (6 AMINOPURIN 9 YL) 1 HYDROXYMETHYLCYCLOPENTANE 1,2 DIOL; 4 (6 AMINOPURIN 9 YL) 2 HYDROXYMETHYLBICYCLO[3.1.0]HEXANE 2,3 DIOL; 5 (6 AMINOPURIN 9 YL) 2 HYDROXYMETHYLCYCLOPENT 3 ENE 1,2 DIOL; 5 HYDROXYMETHYL 2,2 DIMETHYL 5 VINYL[1,3]DIOXOLAN 4 YL]PROP 2 EN 1 OL; 9 [4,5 DIHYDROXY 4 HYDROXYMETHYLCYCLOPENT 2 ENYL] 1,9 DIHYDROPURIN 6 ONE; ADENOSINE RECEPTOR STIMULATING AGENT; ADENOSYLHOMOCYSTEINASE; ARISTEROMYCIN; CARBOCYCLIC NUCLEOSIDE; DICHLOROMETHANE; NEPLANOCIN A; POTASSIUM CARBONATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOLOGICAL ACTIVITY; CATALYST; CHEMICAL REACTION; CYCLOPROPANATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROGENATION; METHYLATION; MITSUNOBU REACTION; OXIDATION; POLYMERIZATION; SIMMONS SMITH REACTION; STEREOCHEMISTRY;

ADENOSINE; ADENOSYLHOMOCYSTEINASE; COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME INHIBITORS; MOLECULAR STRUCTURE; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1;

EID: 20844446829     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0503207     Document Type: Article

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