Polycystic ovary syndrome: An overview

Reviews in Gynaecological Practice

Volumn 5, Issue 2, 2005, Pages 115-122

  Bako, Abdulmalik U ^a   Morad, Sharon ^a   Atiomo, William A ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Clomifene; Insulin resistance; Metformin; Polycystic ovary syndrome

Indexed keywords

ANDROGEN; CLOMIFENE CITRATE; CYPROTERONE ACETATE; DIANE; GONADOTROPIN; METFORMIN; ORAL CONTRACEPTIVE AGENT; SPIRONOLACTONE;

ANDROGEN METABOLISM; ANOVULATION; CARDIOVASCULAR RISK; CLINICAL FEATURE; CLINICAL TRIAL; DIARRHEA; DIATHERMY; ECHOGRAPHY; ENDOMETRIUM CANCER; FEMALE; FEMALE INFERTILITY; HIGH RISK PATIENT; HIRSUTISM; HORMONE ACTION; HUMAN; HYPERANDROGENISM; HYPERKALEMIA; HYPOGLYCEMIA; HYPONATREMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LACTIC ACIDOSIS; LAPAROSCOPIC SURGERY; LIVER TOXICITY; MENSTRUATION DISORDER; NAUSEA; NEPHROTOXICITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OLIGOMENORRHEA; OVARY POLYCYSTIC DISEASE; OVULATION INDUCTION; PATHOPHYSIOLOGY; PELVIS RADIOGRAPHY; PREVALENCE; REVIEW; RISK ASSESSMENT; RISK FACTOR; VOMITING;

EID: 20844444479     PISSN: 14717697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rigp.2005.04.001     Document Type: Review

References (48)

1. S. Franks Polycystic ovary syndrome N Engl J Med 333 1995 853-861
2. A. Dunaif Insulin resistance and the polycystic ovary syndrome: mechanisms and implication for pathogenesis Endocr Rev 18 1997 774-800
3. J. Lord T. Wilkin Metformin in polycystic ovary syndrome Curr Opin Obstet Gynecol 16 6 2004 481-486
4. K.F. Michelmore A.H. Balen D.B. Dunger M.P. Vassey Polycystic ovaries and associated clinical and biochemical features in young women Clin Endocrinol 51 1999 779-786
5. B. Fauser B. Tarlatzis J. Chang R. Azziz R. Legro D. Dewailly et al. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic syndrome (PCOS) Hum Reprod 19 2004 41-47
6. J. Adams D.W. Polson S. Franks Prevalence of polycentric ovaries in women with anovulation and idiopathic hirsutism BMJ 293 1986 355-359
7. A. Abdel Gadir M.S. Khatim R.S. Mowaf H.M. Alnaser N.S. Muharib R.W. Shaw Implications of ultrasonically diagnosed polycystic ovaries. I. Correlations with basal hormonal profiles Hum Reprod 7 1992 453-457
8. J.B. O'Driscoll H. Mamtora J. Higginson A. Pollock J. Kane D.C. Anderson A prospective study of the prevalence of clearcut endocrine disorders and polycystic ovaries in 350 patients presenting with hirsutism or androgenic alopecia Clin Endocrinol 41 1994 231-236
9. J.L. Cresswell D.J. Barker C. Osmond P. Egger D.I. Phillips R.B. Fraser Fetal growth, length of gestation, and polycystic ovaries in adult life Lancet 350 1997 1131-1135
10. D.W. Polson J. Adams J. Wadsworth S. Franks Polycystic ovaries - a common finding in normal women Lancet 1 1998 870-872
11. R.N. Clayton V. Ogden J. Hodgkinson L. Worswick D.A. Rodin S. Dyer T.W. Meade How common are polycystic ovaries in normal women and what is their significance for the fertility of the population? Clin Endocrinol 37 1992 127-134
12. C.N. Wijeyaratne A.H. Balen J.H. Barth P.E. Belchetz Clinical manifestations and insulin resistance (IR) in polycystic ovary syndrome (PCOS) among South Asians and Caucasians: Is there a difference? Clin Endocrinol 57 2002 343-350
13. D.A. Rodin G. Bano J.M. Bland K. Taylor S.S. Nussey Polycystic ovaries and associated metabolic abnormalities in Indian subcontinent Asian women Clin Endocrinol 49 1998 91-99
14. R.S. Legro Polycystic ovary syndrome: Current and future treatment paradigms Am J Obstet Gynecol 179 1998 S101-S108
15. Amato P, Simpson JL. The genetics of polycystic ovary syndrome. In: Arulkumaran S, editor. Clin Obstet Gynaecol 2004;18(5):707-718.
16. A.H. Balen The pathogenesis of polycystic ovary syndrome: The enigma unravels Lancet 354 1999 966-967
17. A.H. Balen G.S. Conway G. Kaltsas Polycystic ovary syndrome: The spectrum of the disorder in 1741 patients Hum Reprod 10 8 1995 2107-2111
18. A. Balen The current understanding of polycystic ovary syndrome TOG 6 2004 66-74
19. A. Gambineri C. Pelusi S. Genghini et al. Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome Clin Endocrinol 60 2004 241-249
20. R. Homburg N.A. Armar Eshel et al. Influence of serum luteinising hormone concentration on ovulation, conception, and early pregnancy loss in polycystic ovary syndrome BMJ 297 1988 1024-1026
21. van der Spuy ZM, Dyer SJ. The pathogenesis of infertility and early pregnancy loss in polycystic ovary syndrome. In: Arulkumaran S, editor. Clin Obstet Gynaecol 2004;18(5):755-771.
22. M. Rebuffe-Scrive G. Cullerg P.A. Lundberg et al. Anthropometric variables and metabolism in polycystic ovarian disease Horm Metab Res 21 1989 391-397
23. Royal College of Obstetricians and Gynaecologists. Long-term consequence of polycystic ovary syndrome. Guideline no. 33, London: RCOG; 2003.
24. Lord JM, Flight IHK, Norman RJ. Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome. The cochrane database of systematic reviews, issue 2; 2003.
25. P. Moghetti R. Castello C. Negri et al. Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: A randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation J Clin Endocrinol Metab 85 2000 139-146
26. A. Sinha W. Atiomo The role of metformin in the treatment of infertile women with polycystic ovary syndrome TOG 6 2004 145-151
27. NICE 2004. Infertility. Technology appraisal guidance no. 22. Available at http://www.nice.org.uk/page.aspx?o=15724, last accessed January 2004.
28. E.J. Coetzee W.P. Jackson Oral hypoglycaemic in the first trimester and fetal outcome S Afr Med J 65 1984 635-637
29. Farquhar C, Vandekerckhove P, Lilford R. Laparoscopic "drilling" by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. The cochrane database of systematic reviews, issue 1; 2004.
30. A.G. Mulders J.S. Laven M.J. Eijkemans E.G. Hughes B.C. Fauser Patient predictors for outcome of gonadotrophin ovulation induction in women with normogonadotrophic anovulatory infertility: A meta-analysis Hum Reprod Updat 9 5 2003 429-449
31. S.D. Keay N.H. Liversedge V.A. Akande R.S. Mathur J.M. Jenkins Serum IGF-1 concentrations following pituitary desensitisation do not predict the ovarian response to gonodotrophin stimulation prior to IVF Hum Reprod 8 9 2003 797-801
32. C.M. Farquhar K. Williamson G. Gudex N. Johnson J. Garland L. Sadler A randomised controlled trial of laparoscopic ovarian diathermy versus gonadotrophin therapy for women for women with clomiphene resistant polycystic ovarian syndrome Fertil Steril 78 2 2001 404-411
33. H. Gjonnaess Late endocrine effect of ovarian electrocautery in women with polycystic ovary syndrome Fertil Steril 69 1998 697-701
34. A. Felemban S.L. Tan T. Tulandi Laparoscopic treatment of polycystic ovaries with insulated needle cautery: A reappraisal Fertil Steril 73 2000 266-269
35. T. Tulandi A. Saleh D. Morris H.S. Jacobs N.N. Payne S.L. Tan Effects of laparoscopic ovarian drilling on serum vascular endothelial growth factor and on insulin responses to the oral glucose tolerance test in women with polycystic ovary syndrome Fertil Steril 74 3 2000 585-588
36. E. Greenblatt R. Casper Adhesion formation after laparoscopic ovarian cautery for polycystic ovarian syndrome: Lack of correlation with pregnancy rate Fertil Steril 60 1993 766-770
37. A.M. Clark B. Thornley L. Tomlinson et al. Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment Hum Reprod 13 1998 1502-1505
38. C. Ayyad T. Andersen Long-term efficacy of dietary treatment of obesity: a systematic review of studies published between 1931 and 1999 Obes Rev 1 2000 113-119
39. Moran L, Norman RJ. Understanding and managing disturbances in insulin metabolism and body weight in women with polycystic ovary syndrome. In: Arulkumaran S, editor. Clin Obstet Gynaecol 2004;18(5):719-736.
40. Hickey M, Higham J, Fraser IS. Progestogens versus oestrogens and progestogens for irregular uterine bleeding associated with anovulation. The cochrane database of systematic reviews, issue 1; 2000.
41. J.H. Barth C.A. Cherry F. Wojnarowska R.P.R. Dawber Cyproterone acetate for severe hirsutism: Results of a double-blind dose-ranging study Clin Endocrinol 35 1991 5-10
42. J.M. Lord I.H.K. Flight R.J. Norman Metformin in polycystic ovary syndrome: Systematic review and meta-analysis BMJ 327 2003 951-956
43. A. Kriplani N. Agarwal Effects of metformin on clinical and biochemical parameters in polycystic ovary syndrome J Reprod Med 49 5 2004 361-367
44. R.A. Wild Long-term health consequences of PCOS Hum Reprod Updat 8 2002 231-241
45. E. Talbot D. Guzick A. Clerici S. Berga K. Detre K. Weimer et al. Coronary heart disease risk factors in women with polycystic ovary syndrome Arterioscler Thromb Vasc Biol 15 1995 821-826
46. C.B. Coulam J.F. Annegers J.S. Kranz Chronic anovulaton syndrome and associated neoplasia Obstet Gynecol 61 1983 403-407
47. A.P. Cheung Ultrasound and menstrual history in predicting endometrial hyperplasia in polycystic ovary syndrome Obstet Gynecol 98 2001 325-331
48. T. Pierpoint P.M. McKeigue A.J. Isaacs S.H. Wild H.S. Jacobs Mortality of women with polycystic ovary syndrome at long-term follow-up J Clin Epidemiol 51 1998 581-586