Dose-dependent liver tissue repair after chloroform plus trichloroethylene binary mixture

Basic and Clinical Pharmacology and Toxicology

Volumn 96, Issue 6, 2005, Pages 436-444

  Anand, Sathanandam S ^a   Mumtaz, Moiz M ^b   Mehendale, Harihara M ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

^b AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CELL DNA; CHLOROFORM; CORN OIL; EOSIN; HEMATOXYLIN; THYMIDINE; TRICHLOROACETIC ACID; TRICHLOROETHANOL; TRICHLOROETHYLENE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; ENZYME ACTIVITY; GAS CHROMATOGRAPHY; HISTOPATHOLOGY; IN VIVO STUDY; LIVER CELL; LIVER INJURY; LIVER LEVEL; LIVER REGENERATION; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE REPAIR; TOXICOKINETICS; URINE LEVEL;

ALANINE TRANSAMINASE; ANIMALS; AREA UNDER CURVE; CHLOROFORM; LIVER; LIVER REGENERATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; TRICHLOROACETIC ACID; TRICHLOROETHYLENE;

ZEA MAYS;

EID: 20644467769     PISSN: 17427835     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2005.pto_96606.x     Document Type: Article

References (42)

1. Anand, S. S., S. N. Murthy, V. S. Vaidya, M. M. Mumtaz & H. M. Mehendale: Tissue repair plays pivotal role in final outcome of supra-additive liver injury after chloroform and allyl alcohol binary mixture. Food Chem. Toxicol. 2003a, 41, 1123-1132.
2. Anand, S. S., M. G. Soni, V. S. Vaidya, S. N. Murthy, M. M. Mumtaz & H. M. Mehendale: Extent and timeliness of tissue repair determines the dose-related hepatotoxicity of chloroform. Int. J. Toxicol. 2003b, 22, 25-33.
3. Anand, S. S., V. S. Vaidya, B. Murali, M. M. Mumtaz & H. M. Mehendale: Hepatotoxicity of chloroform, trichloroethylene, and allyl alcohol ternary mixture is less than additive. The Toxicologist 2003c, 72, 671.
4. Anand, S. S., S. S. Devi, S. N. Murthy, M. M. Mumtaz & H. M. Mehendale: Dose-dependent liver regeneration following co-administartion of Chloroform and trichloroethylene-induced hepatotoxicity in male Sprague-Dawley rats. The Toxicologist 2002, 66, 764.
5. Agency for Toxic Substance and Disease Registry (ATSDR). Haz-Dat. 2001. Atlanta. GA, U.S.A.
6. 3 or trichloroethylene singly and in combination in the rat. Fundam. Appl. Toxicol. 1990, 14, 477-490.
7. Burton, K. A.: A study of the conditions and mechanisms of the diphenylamine reaction for positive colorimetric estimation of DNA. Biochem. J. 1956, 62, 315-323.
8. Chanda, S., R. S. Mangipudy, A. Warbritton, T. J. Bucci & H. M. Mehendale: Stimulated hepatic tissue repair underlies heteroprotection by thioacetamide against acetaminophen-induced lethality. Hepatology 1995, 21, 477-486.
9. Chanda, S. & H. M. Mehendale: Nutritional impact on the final outcome of liver injury inflicted by model hepatotoxicants: effect of glucose loading. FASEB J. 1995, 9, 240-245.
10. Chauveau, J., Y. Moule & C. M. Roniller: Isolation of pure and unaltered liver nuclei morphology and biochemical composition. Exp. Cell. Res. 1956, 11, 317-321.
11. Conolly, R. B. & B. E. Butterworth: Biologically based dose response model for hepatic toxicity: a mechanistically based replacement for traditional estimates of noncancer risk. Toxicol. Lett. 1995, 82, 901-906.
12. Constan, A. A., C. S. Sprankle, J. M. Peters, G. L. Kedderis, J. I. Everitt, B. A. Wong, F. L. Gonzalez & B. E. Butterworth: Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice. Toxicol. Appl. Pharmacol. 1999, 160, 120-126.
13. Dalhoff, K., H. Lausen, K. Bangert, H. E. Poulsen, M. E. Anderson, N. Grunnet & N. Tygstrup: Autoprotection in acetaminophen intoxication in rats: the role of liver regeneration. Pharmacology & Toxicology 2001, 88, 135-141.
14. 3 bioactivation, toxicokinetics, toxicity, and induced compensatory cell proliferation in B6C3F1 male mice. Toxicol. Appl. Pharmacol. 1996, 141, 394-402.
15. Horn, K. D., P. Wax, S. M. Schneider, T. G. Martin, T. G. Nine, A. Moraca, M. A. Virji, P. A. Aronica & K. N. Rao: Biomarkers of liver regeneration allow early prediction of hepatic recovery after acute necrosis. Amer. J. Clin. Pathol. 1999, 112, 351-357.
16. Ikatsu, H. & T. Nakajima: Hepatotoxic interaction between carbon tetrachloride and chloroform in ethanol treated rats. Arch. Toxicol. 1992, 66, 580-586.
17. Inoue, O., K. Seiji, T. Watanabe, M. Kasahara, H. Nakatsuka, S. N. Yin, G. L. Li, S. X. Cai, C. Jin & M. Ikeda:. Mutual metabolic suppression between benzene and toluene in man. Int. Arch. Occup. Environ. Health. 1988, 60, 15-20.
18. Kulkarni, S.G., Duong, H., R. Gomila & H. M. Mehendale: Strain differences in tissue repair response to 1, 2-dichlorobenzene. Arch. Toxicol. 1996, 70, 714-723.
19. Larson, J. L., D. C. Wolf & B. E. Butterworth: Acute hepatotoxic and nephrotoxic effects of chloroform in male F344 rats and female B6C3F1 mice. Fundam. Appl. Toxicol. 1993, 20, 302-315.
20. Larson, J. L. & R. J. Bull: Species differences in the metabolism of trichloroethylene to the carcinogenic metabolites trichloroacetate and dichloroacetate. Toxicol. Appl. Pharmacol. 1992. 115, 278-285.
21. Lilly, P. D., T. M. Ross & T. M. Pegram: Trihalomethane comparative toxicity: Acute renal and hepatic toxicity of chloroform and bromodichloromethane following aqueous gavage. Fundam. Appl. Toxicol. 1997, 40, 101-110.
22. Limaye, P. B., U. M. Apte, T. J. Bucci, A. Warbritton & H. M. Mehendale: Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants. Toxicol. Appl. Pharmacol. 2003, 191, 211-226.
23. Mangipudy, R. S., S. Chanda & H. M. Mehendale: Tissue repair response as a function of dose in thioacetamide hepatotoxicity. Environ. Health Perspect. 1995a, 103, 260-267.
24. Mangipudy, R. S., S. Chanda & H. M. Mehendale: Hepatocellular regeneration: key to thioacetamide autoprotection. Pharmacology & Toxicology 1995b, 77, 182-188.
25. Mangipudy, R. S., P. S. Rao & H. M. Mehendale: Effect of an antimitotic agent colchicine on thioacetamide hepatotoxicity. Environ. Health Perspect. 1996, 104, 744-749.
26. Mangipudy, R. S., P. S. Rao, A. Andrews, C. Fultz, F. A. Witzmann, T. J. Bucci & H. M. Mehendale: Dose-dependent modulation of cell death apoptosis vs. necrosis in thioacetamide hepatotoxicity. Int. J. Toxicol. 1998, 17, 193-211.
27. Mehendale, H. M.: Amplified interactive toxicity of chemicals at nontoxic levels: Mechanistic considerations and implications to public health. Environ. Health Perspect. 1994, 102, 139-149.
28. Mehendale, H. M.: Toxicodynamics of low level toxicant interactions of biological significance: inhibition of tissue repair. Toxicology 1995, 105, 251-266.
29. Mehendale, H. M.: Tissue Repair: an important determinant of final outcome of toxicant-induced injury. Toxicol. Pathol. 2005. 33, 1-10.
30. 3 hepatotoxicity. Exp. Mol. Pathol. 1989, 51, 31-47.
31. Muralidhara, S. & J. V. Bruckner: Simple method for rapid measurement of trichloroethylene and its major metabolites in biological samples. J. Chromatog. 1999, 732, 145-153.
32. Ramaiah, S. K., U. M. Apte & H. M. Mehendale: Diet restriction as a protective mechanism in non-cancer toxicity outcomes: A review. Int. J. Toxicol. 2000, 19, 413-424.
33. Rao, K. N., M. A. Virji, M. A. Moraca, W. F. Diven, T. G. Martin & S. M. Schneider: Role of serum markers for liver function and liver regeneration in the management of chloroform poisoning. J. Anal. Toxicol. 1993, 17, 99-102.
34. Rao, P. S., A. Dalu, S. G. Kulkarni & H. M. Mehendale: Stimulated tissue repair prevents lethality in isopropanol-induced potentiation of carbon tetrachloride hepatotoxicity. Toxicol. Appl. Pharmacol. 1996, 140, 235-244.
35. 4 hepatotoxicity: a novel dose-response. Toxicology 1997, 118, 181-193.
36. Seiji, K., O. Inoue, C. Jin, Y. T. Liu, S. X. Cai, M. Ohashi, T. Watanabe, H. Nakatsuka, T. Kawai & M. Ikeda: Dose-excretion relationship in tetrachloroethylene-exposed workers and the effect of tetrachloroethylene co-exposure on trichloroethylene metabolism. Amer. J. Ind. Med. 1989, 16, 675-684.
37. Soni, M. G. & H. M. Mehendale: Role of tissue repair in toxicological interactions among hepatotoxic organics. Environ. Health Perspect. 1998, 106, 1301-1307.
38. Soni, M. G., R. S. Mangipudy, M. M. Mumtaz & H. M. Mehendale: Tissue repair response as a function of dose during trichloroethylene hepatotoxicity. Toxicol. Sci. 1998, 42, 158-165.
39. Soni, M. G., S. K. Ramaiah, M. M. Mumtaz, H. Clewell & H. M. Mehendale:. Toxicant- inflicted injury and stimulated tissue repair are opposing toxicodynamic forces in predictive toxicology. Regulat. Phramcol. Toxicol. 1999, 19, 165-174.
40. Steup, D R., D. Wiersma, D A. McMillan & I.G. Sipes: Pretreatment with drinking water solutions containing trichloroethylene or chloroform enhances the hepatotoxicity of carbon tetrachloride in Fischer 344 rats. Fundam. Appl. Toxicol. 1991, 16, 798-809.
41. 4 autoprotection. Toxicol. Pathol. 1994, 22, 291-299.
42. Wroblewski, F. & J. S. LaDue: Serum glutamic-pyruvic transaminase in cardiac and hepatic disease. Proc. Soc. Exper. Biol. Med. 1956, 91, 569-574.