Identification of degradation products of diclofenac by electrospray ion trap mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 38, Issue 4, 2005, Pages 790-796

  Galmier, Marie Josèphe ^a,b   Bouchon, Bernadette ^a,b   Madelmont, Jean Claude ^b   Mercier, Fabrice ^c   Pilotaz, Frédéric ^c   Lartigue, Claire ^a,b  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b INSERM   (France)

^c Laboratoires Thea   (France)

Author keywords

Degradation products; Diclofenac; Electrospray ionization ion trap mass spectrometry; Liquid chromatography mass spectrometry

Indexed keywords

1 (2,6 DICHLOROPHENYL)INDOLIN 2 ONE; 2 [(2,6 DICHLOROPHENYL)AMINO]BENZALDEHYDE; [2 [(2,6 DICHLOROPHENYL)AMINO]PHENYL]METHANOL; DICLOFENAC; DRUG METABOLITE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; AQUEOUS SOLUTION; ARTICLE; CYCLIZATION; DRUG IDENTIFICATION; ELECTROSPRAY MASS SPECTROMETRY; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DICLOFENAC; DRUG STABILITY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; INDICATORS AND REAGENTS; SOLUTIONS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; WATER;

EID: 20644467462     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2005.02.016     Document Type: Article

References (20)

1. K.J. Volk, S.E. Klohr, R.A. Rourick, E.H. Kerns, and M.S. Lee J. Pharm. Biomed. 14 1996 1663 1674
2. Y. Wu Biomed. Chromatogr. 14 2000 384 396
3. K. Pennanen, T. Kotiaho, K. Huikko, and R. Kostiainen J. Mass Spectrom. 36 2001 791 797
4. H. Ye, and M. Zhang Chinese Pharm. J. 35 3 2000 192 194
5. M.S. Aurora-Prado, M. Steppe, M.F.M. Tavares, E.R.M. Kedor-Hackmann, and M.I.R.M. Santoro J. AOAC Int. 85 2 2002 330 340
6. L. Seng-Chung, and T. Tung-Hu J. Chromatogr. B 769 2 2002 351 356
7. R. Hajkova, P. Solich, M. Pospigilovad, and J. Sicha Anal. Chim. Acta 467 1/2 2002 91 96
8. M.C. Gaudiano, L. Valvo, P. Bertocchi, and L. Manna J. Pharm. Biomed. 32 2003 151 158
9. M.E. Abdel-Hamid, L. Novotny, and H. Hamza J. Pharm. Biomed. 24 4 2001 587 594
10. O. Corcoran, J.K. Nicholson, E.M. Lenz, F. Abou-Shakra, J. Castro-Perez, A.B. Sage, and I.D. Wilson Rapid Commun. Mass Spectrom. 14 2000 2377 2384
11. C.J. Duckett, N.J.C. Bailey, H. Walker, F. Abou-Shakra, I.D. Wilson, J.C. Lindon, and J.K. Nicholson Rapid Commun. Mass Spectrom. 16 2002 245 247
12. X.S. Miao, B.G. Koenig, and C.D. Metcalfe J. Chromatogr. A. 952 2002 139 147
13. L.G. Lala, P.M. D'Mello, and S.R. Naik J. Pharm. Biomed. 29 2002 539 544
14. R. Andreozzi, M. Raffaele, and P. Nicklas Chemosphere 50 2003 1319 1330
15. European pharmacopoeia, 5th ed., Direction de la Qualité du Médicament du Conseil de l'Europe (2) (2005) 1532-1534.
16. M. Zajac, B. Stanisz, and W. Musial Acta Pol. Pharm. Drug Res. 55 5 1998 371 374
17. M.E. Palomo, M.P. Ballesteros, and P. Frutos J. Pharm. Biomed. 21 1 1999 83 94
18. P. Tudja, M.Z.I. Khan, E. Mestrovic, M. Horvat, and P. Golja Chem. Pharm. Bull. 49 10 2001 1245 1250
19. J. Roy, M. Islam, A.H. Khan, S.C. Das, M. Akhteruzzamam, A.K. Deb, and A.H. Mahbub Alam J. Pharm. Sci. 90 5 2001 541 544
20. D. Vogna, R. Marotta, A. Napolitano, R. Andreozzi, and M. Ischia Water Res. 38 2 2004 414 422