Diclofenac sodium injection sterilized by autoclave and the occurrence of cyclic reaction producing a small amount of impurity

Journal of Pharmaceutical Sciences

Volumn 90, Issue 5, 2001, Pages 541-544

  Roy, Jiben ^a   Islam, Mafizul ^a   Khan, Anowar H ^a   Das, Subodh C ^a   Akhteruzzaman, M ^a   Deb, Ajay K ^a   Mahbub Alam, A H ^a  

^a Square Centre ^*  (Bangladesh)

Author keywords

Diclofenac sodium; Impurity; Injection; Intramolecular cyclization; Reaction kinetics; Sterilization

Indexed keywords

1 (2,6 DICHLOROPHENYL)INDOLIN 2 ONE; DICLOFENAC; EXCIPIENT; INDOLE DERIVATIVE; SODIUM HYDROXIDE; UNCLASSIFIED DRUG;

ARTICLE; AUTOCLAVE; CYCLIZATION; DRUG FORMULATION; DRUG IMPURITY; ENERGY; FILTRATION; INJECTION; INSTRUMENT STERILIZATION; KINETICS; PH; REACTION ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0035038307     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/1520-6017(200105)90:5<541::AID-JPS1011>3.0.CO;2-O     Document Type: Article

References (5)