Taurine has a protective effect against thioacetamide-induced liver cirrhosis by decreasing oxidative stress

Human and Experimental Toxicology

Volumn 20, Issue 5, 2001, Pages 251-254

  Uysal, M ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Antioxidants; Lipid peroxidation; Liver cirrhosis; Rats; Taurine; Thioaceramide

Indexed keywords

ALKADIENE; ALPHA TOCOPHEROL; ASCORBIC ACID; DRINKING WATER; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID; MALONALDEHYDE; SUPEROXIDE DISMUTASE; TAP WATER; TAURINE; THIOACETAMIDE;

ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; EXPERIMENTAL LIVER CIRRHOSIS; HISTOPATHOLOGY; LIPID OXIDATION; LIVER; LIVER PROTECTION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; CARCINOGENS; GLUTATHIONE; LIVER; LIVER CIRRHOSIS; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; TAURINE; THIOACETAMIDE;

ANIMALIA;

EID: 20644461914     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/096032701678227758     Document Type: Article

References (5)

1. Bruck R, et al. The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure. J Hepatol 1999; 31: 27-38.
2. Müller A, Machnik F, Zimmermann T, Schubert H. Thioacetamide-induced cirrhosis-like liver lesions in rats usefulness and reliability of this animal model. Exp Pathol 1988; 34: 229-236.
3. Müller D, et al. Lipid peroxidation in thioacetamide-induced macronodular rat liver cirrhosis. Arch Toxicol 1991; 65: 199-203.
4. 2 in thioacetamide-induced liver cirrhosis. Exp Toxicol Pathol 1997; 49: 141-146.
5. Diez-Fernandez C, et al. Influence of aminoguanidine on parameters of liver injury and regeneration induced in rats by a necrogenic dose of thioacetamide. Br J Pharmacol 1998; 125: 102-108.