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Volumn 31, Issue 1, 1999, Pages 27-38

The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure

Author keywords

Dimethylsulfoxide; Fulminant hepatitis; N acetylcysteine; Nitric oxide; Thioacetamide; Tumor necrosis factor

Indexed keywords

ACETYLCYSTEINE; DIMETHYL SULFOXIDE; DIMETHYLTHIOUREA; GLUTATHIONE; HYDROXYL RADICAL; MALONALDEHYDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PENTOXIFYLLINE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SULFINIC ACID DERIVATIVE; THIOACETAMIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0033035268     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(99)80160-3     Document Type: Article
Times cited : (135)

References (76)
  • 1
    • 0027293230 scopus 로고
    • Acute liver failure: Redefining the syndrome
    • O'Grady J, Schalman SW, Williams R. Acute liver failure: redefining the syndrome. Lancet. 324:1993;273-275.
    • (1993) Lancet , vol.324 , pp. 273-275
    • O'Grady, J.1    Schalman, S.W.2    Williams, R.3
  • 2
    • 0027919071 scopus 로고
    • Acute liver failure
    • Lee WR. Acute liver failure. N Engl J Med. 329:1993;1862-1872.
    • (1993) N Engl J Med , vol.329 , pp. 1862-1872
    • Lee, W.R.1
  • 4
    • 0016909032 scopus 로고
    • Levodopa in the treatment of hepatic coma due to fulminant hepatic failure
    • Mehta JM, Karamarkar SG, Pimparkar BD, Sheth UK. Levodopa in the treatment of hepatic coma due to fulminant hepatic failure. J Postgrad Med. 22:1976;32-36.
    • (1976) J Postgrad Med , vol.22 , pp. 32-36
    • Mehta, J.M.1    Karamarkar, S.G.2    Pimparkar, B.D.3    Sheth Gbr4
  • 5
  • 6
    • 0018742220 scopus 로고
    • Longterm extra-corporeal assistance by continuous haemofiltration during fulminant hepatic failure
    • Denis J, Opolon P, Delorme ML, Granger A, Darnis F. Longterm extra-corporeal assistance by continuous haemofiltration during fulminant hepatic failure. Gastroenterol Clin Biol. 3:1979;337-348.
    • (1979) Gastroenterol Clin Biol , vol.3 , pp. 337-348
    • Denis, J.1    Opolon, P.2    Delorme, M.L.3    Granger, A.4    Darnis, F.5
  • 8
    • 0002636070 scopus 로고
    • Fulminant and subfulminant liver failure
    • N McIntyre, JP Benhamou, J Bircher, M Rizzeto, & J Rodes. Oxford: Oxford University Press
    • Bernuau J, Benhamou JP. Fulminant and subfulminant liver failure. McIntyre N, Benhamou JP, Bircher J, Rizzeto M, Rodes J, . Oxford Textbook of Clinical Hepatology. 1991;942 Oxford University Press, Oxford.
    • (1991) Oxford Textbook of Clinical Hepatology , pp. 942
    • Bernuau, J.1    Benhamou, J.P.2
  • 9
    • 0024502916 scopus 로고
    • Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: Characterization of an improved model and study of amino acid-ergic neurotransmission
    • Zimmermann C, Ferenci P, Pifl C, Yurdaydin C, Ebner J, Lassmann H, et al. Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: characterization of an improved model and study of amino acid-ergic neurotransmission. Hepatology. 9:1989;595-601.
    • (1989) Hepatology , vol.9 , pp. 595-601
    • Zimmermann, C.1    Ferenci, P.2    Pifl, C.3    Yurdaydin, C.4    Ebner, J.5    Lassmann, H.6
  • 10
    • 0027938326 scopus 로고
    • Cerebral blood flow autoregulation is absent in rats with thioacetamide-induced hepatic failure
    • Larsen FS, Knudsen GM, Paulson OB, Vilstrup H. Cerebral blood flow autoregulation is absent in rats with thioacetamide-induced hepatic failure. J Hepatol. 21:1994;491-495.
    • (1994) J Hepatol , vol.21 , pp. 491-495
    • Larsen, F.S.1    Knudsen, G.M.2    Paulson, O.B.3    Vilstrup, H.4
  • 11
    • 0021238748 scopus 로고
    • Role of the microsomal FAD-containing monooxygenase in the liver toxicity of thioacetamide S-oxide
    • Chieli E, Malvaldi G. Role of the microsomal FAD-containing monooxygenase in the liver toxicity of thioacetamide S-oxide. Toxicology. 31:1984;41-52.
    • (1984) Toxicology , vol.31 , pp. 41-52
    • Chieli, E.1    Malvaldi, G.2
  • 12
    • 0018103109 scopus 로고
    • Metabolism of thioacetamide and thioacetamide S-oxide by rat liver microsomes
    • Porter WR, Neal RA. Metabolism of thioacetamide and thioacetamide S-oxide by rat liver microsomes. Drug Metab Dispos. 6:1978;379-388.
    • (1978) Drug Metab Dispos , vol.6 , pp. 379-388
    • Porter, W.R.1    Neal, R.A.2
  • 13
    • 0017331152 scopus 로고
    • Thioactamide-induced hepatic necrosis. Involvement of the mixed-function oxidase enzyme system
    • Hunter AL, Holscher MA, Neal RA. Thioactamide-induced hepatic necrosis. Involvement of the mixed-function oxidase enzyme system. J Pharmacol Exp Ther. 200:1977;439-448.
    • (1977) J Pharmacol Exp Ther , vol.200 , pp. 439-448
    • Hunter, A.L.1    Holscher Ma2    Neal, R.A.3
  • 14
    • 0021763962 scopus 로고
    • Free radical mechanisms in tissue injury
    • Slater TF. Free radical mechanisms in tissue injury. Biochem J. 222:1984;1-15.
    • (1984) Biochem J , vol.222 , pp. 1-15
    • Slater, T.F.1
  • 15
    • 0023464342 scopus 로고
    • Free radical tissue damage: Protective role of anti oxidant nutrients
    • Machlin LJ, Bendich A. Free radical tissue damage: protective role of anti oxidant nutrients. FASEB J. 1:1987;441-445.
    • (1987) FASEB J , vol.1 , pp. 441-445
    • Machlin, L.J.1    Bendich, A.2
  • 17
    • 0023583835 scopus 로고
    • Superoxide dismutase and catalase protect cultured hepatocytes from the cytotoxicity of acetaminophen
    • Kyle ME, Miccadei S, Nakae D, Farber JL. Superoxide dismutase and catalase protect cultured hepatocytes from the cytotoxicity of acetaminophen. Biochem Biophys Res Commun. 149:1987;889-896.
    • (1987) Biochem Biophys Res Commun , vol.149 , pp. 889-896
    • Kyle, M.E.1    Miccadei, S.2    Nakae, D.3    Farber, J.L.4
  • 18
    • 0019511768 scopus 로고
    • Ethanol induced lipid peroxidation: Potentiation by long-term alcohol feeding and attenuation by methionine
    • Shaw S, Jayatilleke E, Ross WA, Gordon E, Lieber CS. Ethanol induced lipid peroxidation: potentiation by long-term alcohol feeding and attenuation by methionine. J Lab Clin Med. 98:1981;417-424.
    • (1981) J Lab Clin Med , vol.98 , pp. 417-424
    • Shaw, S.1    Jayatilleke, E.2    Ross, W.A.3    Gordon, E.4    Lieber, C.S.5
  • 20
    • 0028847434 scopus 로고
    • 4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding
    • 4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding. Hepatology. 22:1995;1474-1481.
    • (1995) Hepatology , vol.22 , pp. 1474-1481
    • Liu, S.L.1    Esposti, S.D.2    Yao, T.3    Diehl, A.M.4    Zern Ma5
  • 21
    • 0031016132 scopus 로고    scopus 로고
    • Effect of vitamin E supplementation on hepatic fibrogenesis in chronic dietary iron overload
    • Brown KE, Poulos JE, Li L, Soweid AM, Ramm GA, O'Neil R, et al. Effect of vitamin E supplementation on hepatic fibrogenesis in chronic dietary iron overload. Am J Physiol. 272:1997;G116-G123.
    • (1997) Am J Physiol , vol.272
    • Brown, K.E.1    Poulos, J.E.2    Li, L.3    Soweid, A.M.4    Ramm, G.A.5    O'Neil, R.6
  • 23
    • 0026026639 scopus 로고
    • Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients
    • Khoruts A, Stahnke L, McClain CL, Logan G, Allen J. Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients. Hepatology. 13:1991;267-276.
    • (1991) Hepatology , vol.13 , pp. 267-276
    • Khoruts, A.1    Stahnke, L.2    McClain, C.L.3    Logan, G.4    Allen, J.5
  • 24
    • 0027296643 scopus 로고
    • Increased plasma interleukin-8 concentrations in alcoholic hepatitis
    • Hill DB, Marsano LS, McClain CJ. Increased plasma interleukin-8 concentrations in alcoholic hepatitis. Hepatology. 18:1993;576-580.
    • (1993) Hepatology , vol.18 , pp. 576-580
    • Hill, D.B.1    Marsano, L.S.2    McClain, C.J.3
  • 26
    • 0024314274 scopus 로고
    • Thein vitro andin vivo association of transforming growth factor- With hepatic fibrosis
    • Czaja MJ, Weiner FR, Flanders KC, Giambrone MA, Wind R, Biempica L, et al. Thein vitro andin vivo association of transforming growth factor- with hepatic fibrosis. J Cell Biol. 108:1989;2477-2482.
    • (1989) J Cell Biol , vol.108 , pp. 2477-2482
    • Czaja, M.J.1    Weiner, F.R.2    Flanders, K.C.3    Giambrone Ma4    Wind, R.5    Biempica, L.6
  • 27
    • 0024587645 scopus 로고
    • Increased tumor necrosis factor production by monocytes in alcoholic hepatitis
    • McClain CJ, Cohen DA. Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology. 9:1989;349-351.
    • (1989) Hepatology , vol.9 , pp. 349-351
    • McClain, C.J.1    Cohen, D.A.2
  • 28
    • 0024442472 scopus 로고
    • Tumor necrosis factor-α production by peripheral blood mononuclear cells of patients with chronic liver disease
    • Yoshioka K, Kakumu S, Arao M, Tsutsumi Y, Inoue M. Tumor necrosis factor-α production by peripheral blood mononuclear cells of patients with chronic liver disease. Hepatology. 10:1989;769-773.
    • (1989) Hepatology , vol.10 , pp. 769-773
    • Yoshioka, K.1    Kakumu, S.2    Arao, M.3    Tsutsumi, Y.4    Inoue, M.5
  • 29
    • 0023175468 scopus 로고
    • Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine treated mice
    • Lehman V, Freudenberg MA, Galanos C. Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine treated mice. J Exp Med. 165:1987;657-663.
    • (1987) J Exp Med , vol.165 , pp. 657-663
    • Lehman, V.1    Freudenberg Ma2    Galanos, C.3
  • 30
    • 0025225649 scopus 로고
    • Involvement of tumor necrosis factor- In development of hepatic injury in galactosamine sensitized mice
    • Hishinuma I, Nagakawa KI, Hirota K, Miyamoto K, Tsukidate K, Yamanaka T, et al. Involvement of tumor necrosis factor- in development of hepatic injury in galactosamine sensitized mice. Hepatology. 12:1990;1187-1191.
    • (1990) Hepatology , vol.12 , pp. 1187-1191
    • Hishinuma, I.1    Nagakawa, K.I.2    Hirota, K.3    Miyamoto, K.4    Tsukidate, K.5    Yamanaka, T.6
  • 31
    • 0029015685 scopus 로고
    • Prevention of carbon tetrachloride-induced liver injury by soluble tumor necrosis factor receptor
    • Czaja MJ, Xu J, Alt A. Prevention of carbon tetrachloride-induced liver injury by soluble tumor necrosis factor receptor. Gastroenterology. 108:1995;1849-1854.
    • (1995) Gastroenterology , vol.108 , pp. 1849-1854
    • Czaja, M.J.1    Xu, J.2    Alt, A.3
  • 32
    • 0028279345 scopus 로고
    • The induction of MnSOD gene expression in a hepatic model of TNF-α toxicity does not result in increased protein
    • Czaja MJ, Schilsky ML, Xu Y, Schmiedeberg P, Compton A, Ridnour L, et al. The induction of MnSOD gene expression in a hepatic model of TNF-α toxicity does not result in increased protein. Am J Physiol. 266:1994;G737-G744.
    • (1994) Am J Physiol , vol.266
    • Czaja, M.J.1    Schilsky, M.L.2    Xu, Y.3    Schmiedeberg, P.4    Compton, A.5    Ridnour, L.6
  • 33
    • 0020664865 scopus 로고
    • Mechanism of action of N-acetylcysteine in the protection against the hepatotoxicity of acetaminophen in ratsin vivo
    • Lauterburg BH, Corcoran GB, Mitchell JR. Mechanism of action of N-acetylcysteine in the protection against the hepatotoxicity of acetaminophen in ratsin vivo. J Clin Invest. 71:1983;980-991.
    • (1983) J Clin Invest , vol.71 , pp. 980-991
    • Lauterburg, B.H.1    Corcoran, G.B.2    Mitchell Jr3
  • 34
    • 0023698302 scopus 로고
    • Antidotal effectiveness ofN-acetylcysteine in reversing acetaminophen-induced hepatotoxicity
    • Bruno MK, Cohen SD, Khairallah EA. Antidotal effectiveness ofN-acetylcysteine in reversing acetaminophen-induced hepatotoxicity. Biochem Pharmacol. 37:1988;4319-4325.
    • (1988) Biochem Pharmacol , vol.37 , pp. 4319-4325
    • Bruno, M.K.1    Cohen, S.D.2    Khairallah, E.A.3
  • 35
    • 84970332080 scopus 로고
    • Survival after massive ingestional carbon tetrachloride treated by intravenous infusion of acetylcysteine
    • Mathieson PW, Williams G, MacSweeney JE. Survival after massive ingestional carbon tetrachloride treated by intravenous infusion of acetylcysteine. Hum Toxicol. 4:1985;627-631.
    • (1985) Hum Toxicol , vol.4 , pp. 627-631
    • Mathieson, P.W.1    Williams, G.2    MacSweeney, J.E.3
  • 36
    • 0027752805 scopus 로고
    • The L-argininitric oxide pathway
    • Moncada S, Higgs. The L-argininitric oxide pathway. N Engl J Med. 329:1993;2002-2010.
    • (1993) N Engl J Med , vol.329 , pp. 2002-2010
    • Moncada, S.1    Higgs2
  • 37
    • 0028955709 scopus 로고
    • The delicate balance of nitric oxide and superoxide in liver pathology
    • Billiar TR. The delicate balance of nitric oxide and superoxide in liver pathology. Gastroenterology. 108:1995;603-605.
    • (1995) Gastroenterology , vol.108 , pp. 603-605
    • Billiar, T.R.1
  • 38
    • 0001373148 scopus 로고
    • An rat model of hepatic encephalopathy due to fulminant hepatic failure: The role of supportive therapy
    • PB Soeters, JHP Wilson, AJ Meijer, & E Holm. Amsterdam: Elsevier Science Publishers
    • Geller D. An rat model of hepatic encephalopathy due to fulminant hepatic failure: the role of supportive therapy. Soeters PB, Wilson JHP, Meijer AJ, Holm E, . Advances in Ammonia Metabolism and Hepatic Encephalopathy. 1988;213-217 Elsevier Science Publishers, Amsterdam.
    • (1988) Advances in Ammonia Metabolism and Hepatic Encephalopathy , pp. 213-217
    • Geller, D.1
  • 39
    • 0014529898 scopus 로고
    • Lipid peroxide formation in microsomes
    • Niehaus WG, Samuelsson JR, Wills ED. Lipid peroxide formation in microsomes. Biochem J. 113:1969;315-341.
    • (1969) Biochem J , vol.113 , pp. 315-341
    • Niehaus, W.G.1    Samuelsson Jr2    Wills, E.D.3
  • 40
    • 0024988291 scopus 로고
    • Detection and quantitation of hydroxyl radical using dimethyl sulfoxide as molecular probe
    • Babbs CF, Steiner MG. Detection and quantitation of hydroxyl radical using dimethyl sulfoxide as molecular probe. Methods Enzymol. 186:1990;137-147.
    • (1990) Methods Enzymol , vol.186 , pp. 137-147
    • Babbs, C.F.1    Steiner, M.G.2
  • 41
    • 0010979836 scopus 로고
    • Evaluation of the suitability of galactoseamine-induced fulminant hepatic failure as a model of hepatic encephalopathy in the rat and rabbit
    • PB Soeters, JHP Wilson, AJ Meijer, & E Holm. Amsterdam: Elsevier Science Publishers
    • Mullen KD. Evaluation of the suitability of galactoseamine-induced fulminant hepatic failure as a model of hepatic encephalopathy in the rat and rabbit. Soeters PB, Wilson JHP, Meijer AJ, Holm E, . Advances in Ammonia Metabolism and Hepatic Encephalopathy. 1988;205-211 Elsevier Science Publishers, Amsterdam.
    • (1988) Advances in Ammonia Metabolism and Hepatic Encephalopathy , pp. 205-211
    • Mullen, K.D.1
  • 42
    • 0032125209 scopus 로고    scopus 로고
    • Pentoxifylline prevents concanavalin A-induced hepatitis by reducing TNF-α levels and inhibiting adhesion of T lymphocytes to extracellular matrix
    • Shirin H, Bruck R, Aeed H, Frenkel D, Zaidel L, Kenet G, et al. Pentoxifylline prevents concanavalin A-induced hepatitis by reducing TNF-α levels and inhibiting adhesion of T lymphocytes to extracellular matrix. J Hepatol. 29:1998;60-67.
    • (1998) J Hepatol , vol.29 , pp. 60-67
    • Shirin, H.1    Bruck, R.2    Aeed, H.3    Frenkel, D.4    Zaidel, L.5    Kenet, G.6
  • 43
    • 0031049463 scopus 로고    scopus 로고
    • Analysis of Arg-Gly-Asp mimetics and soluble receptor of tumor necrosis factor as therapeutic modalities for concanavalin A-induced hepatitis in mice
    • Bruck R, Shirin H, Hershkoviz R, Lider O, Kenet G, Aeed H, et al. Analysis of Arg-Gly-Asp mimetics and soluble receptor of tumor necrosis factor as therapeutic modalities for concanavalin A-induced hepatitis in mice. Gut. 40:1997;133-138.
    • (1997) Gut , vol.40 , pp. 133-138
    • Bruck, R.1    Shirin, H.2    Hershkoviz, R.3    Lider, O.4    Kenet, G.5    Aeed, H.6
  • 44
    • 0027228499 scopus 로고
    • Prevention of regimen-related toxicities after bone marrow transplantation by pentoxifylline: A prospective randomized trial
    • Attal M, Huguet F, Rubie H, Charlet JP, Schlaifer D, Huynh A, et al. Prevention of regimen-related toxicities after bone marrow transplantation by pentoxifylline: a prospective randomized trial. Blood. 82:1993;732-736.
    • (1993) Blood , vol.82 , pp. 732-736
    • Attal, M.1    Huguet, F.2    Rubie, H.3    Charlet, J.P.4    Schlaifer, D.5    Huynh, A.6
  • 45
    • 0031054601 scopus 로고    scopus 로고
    • Pentoxifyllinein vivo andin vitro down-regulates the expression of the intercellular adhesion molecule-1 in monocytes
    • Neuner P, Klosner G, Pornmojib M, Knobler R, Schwarz T. Pentoxifyllinein vivo andin vitro down-regulates the expression of the intercellular adhesion molecule-1 in monocytes. Immunology. 90:1997;435-439.
    • (1997) Immunology , vol.90 , pp. 435-439
    • Neuner, P.1    Klosner, G.2    Pornmojib, M.3    Knobler, R.4    Schwarz, T.5
  • 46
    • 0026656897 scopus 로고
    • Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma, hemorrhage and resuscitation
    • Wang P, Ba FZ, Morrison MH, Ayala A, Chaudry IH. Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma, hemorrhage and resuscitation. Surgery. 112:1992;451-458.
    • (1992) Surgery , vol.112 , pp. 451-458
    • Wang, P.1    Ba, F.Z.2    Morrison, M.H.3    Ayala, A.4    Chaudry, I.H.5
  • 47
    • 0025946778 scopus 로고
    • Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: A prospective controlled trial
    • Keays R, Harrison PM, Wendon JA, Forbes A, Gove C, Alexander GM, et al. Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial. BMJ. 303:1991;1026-1029.
    • (1991) BMJ , vol.303 , pp. 1026-1029
    • Keays, R.1    Harrison, P.M.2    Wendon, J.A.3    Forbes, A.4    Gove, C.5    Alexander, G.M.6
  • 48
    • 0026432652 scopus 로고
    • Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure
    • Harrison PM, Wendon JA, Gimson AE, Alexander JG, Williams R. Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure. N Engl J Med. 324:1991;1852-1857.
    • (1991) N Engl J Med , vol.324 , pp. 1852-1857
    • Harrison, P.M.1    Wendon, J.A.2    Gimson, A.E.3    Alexander, J.G.4    Williams, R.5
  • 49
    • 0028291629 scopus 로고
    • Cerebral blood flow and metabolism in fulminant liver failure
    • Wendon JA, Harrison PM, Keays R, Williams R. Cerebral blood flow and metabolism in fulminant liver failure. Hepatology. 19:1994;1407-1413.
    • (1994) Hepatology , vol.19 , pp. 1407-1413
    • Wendon, J.A.1    Harrison, P.M.2    Keays, R.3    Williams, R.4
  • 50
    • 0029869775 scopus 로고    scopus 로고
    • Evidence of increased guanylate cyclase activation by acetylcysteine in fulminant hepatic failure
    • Harrison PM, Wendon JA, Williams R. Evidence of increased guanylate cyclase activation by acetylcysteine in fulminant hepatic failure. Hepatology. 23:1996;1067-1072.
    • (1996) Hepatology , vol.23 , pp. 1067-1072
    • Harrison, P.M.1    Wendon, J.A.2    Williams, R.3
  • 51
    • 0029919078 scopus 로고    scopus 로고
    • Changes in rat liver gene expression induced by thioacetamide: Protective role of S-adenosyl-L-methionine by a glutathione-dependent mechanism
    • Mesa ML, Carrizosa R, Marinez-Honduvilla C, Benito M, Fabregat I. Changes in rat liver gene expression induced by thioacetamide: protective role of S-adenosyl-L-methionine by a glutathione-dependent mechanism. Hepatology. 23:1996;600-606.
    • (1996) Hepatology , vol.23 , pp. 600-606
    • Mesa, M.L.1    Carrizosa, R.2    Marinez-Honduvilla, C.3    Benito, M.4    Fabregat, I.5
  • 52
    • 0024573303 scopus 로고
    • An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocytes protein synthesisin vitro
    • Billiar TR, Curran RD, Stuehr DJ, West MA, Bentz BG, Simmons RL. An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocytes protein synthesisin vitro. J Exp Med. 169:1989;1467-1472.
    • (1989) J Exp Med , vol.169 , pp. 1467-1472
    • Billiar, T.R.1    Curran, R.D.2    Stuehr, D.J.3    West Ma4    Bentz, B.G.5    Simmons, R.L.6
  • 53
    • 0027439440 scopus 로고
    • Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes
    • Geller DA, Nussler AK, Di Silvio M, Lowenstein CJ, Shapiro RA, Wang SC, et al. Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci USA. 90:1993;522-526.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 522-526
    • Geller, D.A.1    Nussler, A.K.2    Di Silvio, M.3    Lowenstein, C.J.4    Shapiro, R.A.5    Wang, S.C.6
  • 54
    • 0027494264 scopus 로고
    • Platelet activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide
    • Szabo C, Wu C, Milchel JA, Gross SS, Thiemermann C, Vane JR. Platelet activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide. Circ Res. 73:1993;991-998.
    • (1993) Circ Res , vol.73 , pp. 991-998
    • Szabo, C.1    Wu, C.2    Milchel, J.A.3    Gross, S.S.4    Thiemermann, C.5    Vane Jr6
  • 55
    • 0025051058 scopus 로고
    • Biologically active products of stimulated liver macrophages (Kupffer cells)
    • Decker K. Biologically active products of stimulated liver macrophages (Kupffer cells). Eur J Biochem. 192:1990;245-261.
    • (1990) Eur J Biochem , vol.192 , pp. 245-261
    • Decker, K.1
  • 56
  • 57
    • 0026666826 scopus 로고
    • Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radicalmediated hepatic injury
    • Harbrecht BG, Billiar TR, Stadler J, Demetris AJ, Ochoa J, Curran RD, et al. Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radicalmediated hepatic injury. J Leukoc Biol. 52:1992;390-394.
    • (1992) J Leukoc Biol , vol.52 , pp. 390-394
    • Harbrecht, B.G.1    Billiar, T.R.2    Stadler, J.3    Demetris, A.J.4    Ochoa, J.5    Curran, R.D.6
  • 58
    • 0030829599 scopus 로고    scopus 로고
    • Differential effects of nitric oxide inhibitors on endotoxin-induced liver damage in rats
    • Vos TA, Gouw ASH, Klok PA, Havinga R, Van Goor H, Huitema S, et al. Differential effects of nitric oxide inhibitors on endotoxin-induced liver damage in rats. Gastroenterology. 113:1997;1323-1333.
    • (1997) Gastroenterology , vol.113 , pp. 1323-1333
    • Vos, T.A.1    Gouw Ash2    Klok, P.A.3    Havinga, R.4    Van Goor, H.5    Huitema, S.6
  • 59
    • 0028809984 scopus 로고
    • Inhibition of nitric oxide production increases dimethylnitrosamine-induced liver injury in rats
    • Nagase S, Isobe H, Ayukawa K, Sakai H, Hawata H. Inhibition of nitric oxide production increases dimethylnitrosamine-induced liver injury in rats. J Hepatol. 23:1995;601-604.
    • (1995) J Hepatol , vol.23 , pp. 601-604
    • Nagase, S.1    Isobe, H.2    Ayukawa, K.3    Sakai, H.4    Hawata, H.5
  • 60
    • 0027392508 scopus 로고
    • N omeganitro-L-arginine administration corrects peripheral vasodilatation and systemic capillary hypotension and ameliorates plasma expansion and sodium retention in portal hypertensive rats
    • Lee FY, Colombato LA, Albillos A, Groszmann RJ. N omeganitro-L-arginine administration corrects peripheral vasodilatation and systemic capillary hypotension and ameliorates plasma expansion and sodium retention in portal hypertensive rats. Hepatology. 17:1993;84-90.
    • (1993) Hepatology , vol.17 , pp. 84-90
    • Lee, F.Y.1    Colombato, L.A.2    Albillos, A.3    Groszmann, R.J.4
  • 62
    • 0024311321 scopus 로고
    • Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion
    • McCall TB, Boughton-Smith NK, Palmer RNJ, Whittle BJR, Moncada S. Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion. Biochem J. 261:1989;293-296.
    • (1989) Biochem J , vol.261 , pp. 293-296
    • McCall, T.B.1    Boughton-Smith, N.K.2    Palmer Rnj3    Whittle Bjr4    Moncada, S.5
  • 64
    • 0025233627 scopus 로고
    • The protective action of nitric oxide against membrane damage induced by myoglobin radicals
    • Bruckdorfer KR, Dee G, Jacobs M, Rice-Evans CA. The protective action of nitric oxide against membrane damage induced by myoglobin radicals. Biochem Soc Trans. 18:1990;285-286.
    • (1990) Biochem Soc Trans , vol.18 , pp. 285-286
    • Bruckdorfer, K.R.1    Dee, G.2    Jacobs, M.3    Rice-Evans, C.A.4
  • 65
    • 0020070878 scopus 로고
    • Effects of dimethyl sulfoxide on the globally ischemic heart: Possible general relevance to hypothermic organ preservation
    • Schlafer M, Kane PF, Kirsch M. Effects of dimethyl sulfoxide on the globally ischemic heart: possible general relevance to hypothermic organ preservation. Cryobiology. 19:1982;61-69.
    • (1982) Cryobiology , vol.19 , pp. 61-69
    • Schlafer, M.1    Kane, P.F.2    Kirsch, M.3
  • 67
    • 0016586721 scopus 로고
    • Effects of dimethyl sulfoxide (DMSO) on prostaglandin synthetase
    • LeHann TR, Horita A. Effects of dimethyl sulfoxide (DMSO) on prostaglandin synthetase. Proc West Pharmacol Soc. 18:1975;81-82.
    • (1975) Proc West Pharmacol Soc , vol.18 , pp. 81-82
    • Lehann, T.R.1    Horita, A.2
  • 68
    • 0016409429 scopus 로고
    • The influence of dimethyl sulfoxide on cellular ultrastructure an cytochemistry
    • Sandborn EB, Stephens H, Bendayan M. The influence of dimethyl sulfoxide on cellular ultrastructure an cytochemistry. Ann NY Acad Sci. 243:1975;122-138.
    • (1975) Ann NY Acad Sci , vol.243 , pp. 122-138
    • Sandborn, E.B.1    Stephens, H.2    Bendayan, M.3
  • 69
    • 0016409438 scopus 로고
    • Influence of nonionic organic solutes on various reactions of energy conservation and utilization
    • Conover TE. Influence of nonionic organic solutes on various reactions of energy conservation and utilization. Ann NY Acad Sci. 243:1975;24-37.
    • (1975) Ann NY Acad Sci , vol.243 , pp. 24-37
    • Conover, T.E.1
  • 70
    • 0019494675 scopus 로고
    • The effect of dimethyl sulfoxide on the calcium paradox
    • Ruigrok TJC, DeMoes D, Slade AM, Nayler WG. The effect of dimethyl sulfoxide on the calcium paradox. Am J Pathol. 103:1981;390-403.
    • (1981) Am J Pathol , vol.103 , pp. 390-403
    • Ruigrok Tjc1    Demoes, D.2    Slade, A.M.3    Nayler, W.G.4
  • 71
    • 0029904004 scopus 로고    scopus 로고
    • Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways
    • Massion PP, Linden A, Inoue M, Mathy M, Grattan KM, Nadel. Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways. Am J Physiol. 271:1996;L838-L843.
    • (1996) Am J Physiol , vol.271
    • Massion, P.P.1    Linden, A.2    Inoue, M.3    Mathy, M.4    Grattan, K.M.5    Nadel6
  • 72
    • 0023223364 scopus 로고
    • The specificity of thiourea, dimethylthiourea and dimethyl sulfoxide as scavengers of hydroxyl radicals. Their protection ofα1-antiproteinase against inactivation by hypochlorous acid
    • Wasil M, Halliwell B, Grootveld M, Moorhouse CP, Hutchison DSC, Baum H. The specificity of thiourea, dimethylthiourea and dimethyl sulfoxide as scavengers of hydroxyl radicals. Their protection ofα1-antiproteinase against inactivation by hypochlorous acid. Biochemical J. 243:1987;867-870.
    • (1987) Biochemical J , vol.243 , pp. 867-870
    • Wasil, M.1    Halliwell, B.2    Grootveld, M.3    Moorhouse, C.P.4    Hutchison Dsc5    Baum, H.6
  • 73
    • 0030894671 scopus 로고    scopus 로고
    • Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: Nonspecificity as hydroxyl radical scavengers
    • Whiteman M, Halliwell B. Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: nonspecificity as hydroxyl radical scavengers. Free Rad Biol Med. 22:1997;1309-1312.
    • (1997) Free Rad Biol Med , vol.22 , pp. 1309-1312
    • Whiteman, M.1    Halliwell, B.2
  • 74
    • 0027769724 scopus 로고
    • Effect of dimethyl sulfoxide pretreatment on activities of lipid peroxide and glutathione peroxidase in the mouse liver after whole-body irradiation
    • Ueda T, Toyoshima Y, Kushihashi T, Hishida T, Yashuhara H. Effect of dimethyl sulfoxide pretreatment on activities of lipid peroxide and glutathione peroxidase in the mouse liver after whole-body irradiation. J Toxicol Sci. 18:1993;239-244.
    • (1993) J Toxicol Sci , vol.18 , pp. 239-244
    • Ueda, T.1    Toyoshima, Y.2    Kushihashi, T.3    Hishida, T.4    Yashuhara, H.5
  • 75
    • 0018643565 scopus 로고
    • Generation of hydroxyl radicals by enzymes, chemicals, and human phagocytesin vitro. Detection with the anti-inflammatory agent, dimethyl sulfoxide
    • Repine JE, Eaton JW, Anders MW, Hoidal JR, Fox RB. Generation of hydroxyl radicals by enzymes, chemicals, and human phagocytesin vitro. Detection with the anti-inflammatory agent, dimethyl sulfoxide. J Clin Invest. 64:1979;1642-1651.
    • (1979) J Clin Invest , vol.64 , pp. 1642-1651
    • Repine, J.E.1    Eaton, J.W.2    Anders, M.W.3    Hoidal Jr4    Fox, R.B.5
  • 76
    • 0031066703 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activation by dimethyl sulfoxide correlates with suppression of TNF-alpha formation, reduced ICAM-1 gene transcription, and protection against endotoxin-induced liver injury
    • Essani NA, Fisher MA, Jaeschke H. Inhibition of NF-kappa B activation by dimethyl sulfoxide correlates with suppression of TNF-alpha formation, reduced ICAM-1 gene transcription, and protection against endotoxin-induced liver injury. Shock. 7:1997;90-96.
    • (1997) Shock , vol.7 , pp. 90-96
    • Essani, N.A.1    Fisher Ma2    Jaeschke, H.3


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