Variation in the α2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo

Pharmacogenetics and Genomics

Volumn 15, Issue 6, 2005, Pages 407-414

  Muszkat, Mordechai ^a   Kurnik, Daniel ^a   Solus, Joseph ^c   Sofowora, Gbenga G ^a   Xie, Hong Guang ^a   Jiang, Lan ^b   McMunn, Chara ^c   Ihrie, Patrick ^c   Harris, James R ^c   Dawson, Elliott P ^c   Williams, Scott M ^a,b   Wood, Alastair J J ^a   Stein, C Michael ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c BioVentures Inc   (United States)

Author keywords

ADRA2B; Dexmedetomidine; Genetic variation; Haplotype; Pharmacogenetics; Pharmacogenomics; Polymorphism; Vasoconstriction; Veins; 2B adrenergic receptor

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 2B ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR; DEXMEDETOMIDINE; ALPHA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; PRIMER DNA;

3' UNTRANSLATED REGION; ADRA2B GENE; ADULT; AFRICAN AMERICAN; ALGORITHM; ALLELE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; CAUCASIAN; CONTROLLED STUDY; DOSE RESPONSE; DRUG RESPONSE; DRUG SENSITIVITY; EXON; FEMALE; GENE AMPLIFICATION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HAND; HAPLOTYPE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RACE DIFFERENCE; RECEPTOR DOWN REGULATION; RECEPTOR GENE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; VASOCONSTRICTION; VEIN; ADOLESCENT; BLOOD VESSEL; DRUG EFFECT; GENETICS; GENOTYPE; MIDDLE AGED; PHYSIOLOGY;

ADOLESCENT; ADRENERGIC BETA-AGONISTS; ADULT; BASE SEQUENCE; BLOOD VESSELS; DEXMEDETOMIDINE; DNA PRIMERS; FEMALE; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, GENETIC; RECEPTORS, ADRENERGIC, ALPHA-2; VARIATION (GENETICS); VASOCONSTRICTION;

EID: 20644442662     PISSN: 17446872     EISSN: None     Source Type: Journal    
DOI: 10.1097/01213011-200506000-00006     Document Type: Article

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