Models of ovarian cancer - Are we there yet?

Molecular and Cellular Endocrinology

Volumn 239, Issue 1-2, 2005, Pages 15-26

  Garson, Kenneth ^a   Shaw, Tanya J ^a,b   Clark, Katherine V ^a,b   Yao, De Sheng ^c   Vanderhyden, Barbara C ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c Guangxi Cancer Institute   (China)

Author keywords

Cell transformation; Ovarian cancer; Xenograft models

Indexed keywords

CRE RECOMBINASE; MUELLERIAN INHIBITING SUBSTANCE RECEPTOR TYPE II; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ASCITES; CANCER CELL CULTURE; CANCER GROWTH; CANCER MODEL; CANCER RECURRENCE; CANCER RESISTANCE; CELL TRANSFORMATION; CHEMOSENSITIVITY; DISEASE COURSE; EARLY CANCER; EARLY DIAGNOSIS; ENDOMETRIUM; EPITHELIUM; EPITHELIUM CELL; EXPERIMENTAL MODEL; GENE EXPRESSION; GENETIC ENGINEERING; GENETIC RECOMBINATION; GROWTH REGULATION; GYNECOLOGIC CANCER; HEREDITY; HUMAN; IMMUNE SYSTEM; IN VITRO STUDY; LETHALITY; LOXP SITE; MALIGNANT TRANSFORMATION; MOLECULAR BIOLOGY; NONHUMAN; ONCOGENE; OVARY CANCER; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; RELIABILITY; REVIEW; TRANSGENIC MOUSE; TUMOR XENOGRAFT;

ANIMALS; DISEASE MODELS, ANIMAL; EPITHELIUM; FEMALE; HUMANS; MICE; NEOPLASMS, EXPERIMENTAL; OVARIAN NEOPLASMS; OVARY; PRECANCEROUS CONDITIONS;

EID: 20544475383     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2005.03.019     Document Type: Review

References (51)

1. A. Abdollahi, A.K. Godwin, P.D. Miller, L.A. Getts, D.C. Schultz, T. Taguchi, J.R. Testa, and T.C. Hamilton Identification of a gene containing zinc-finger motifs based on lost expression in malignantly transformed rat ovarian surface epithelial cells Cancer Res. 57 1997 2029 2034
2. A.T. Adams, and N. Auersperg Transformation of cultured rat ovarian surface epithelial cells by Kirsten murine sarcoma virus Cancer Res. 41 1981 2063 2072
3. American Cancer Society, 2003. Cancer facts and figures 2003. 5008.03. Atlanta, GA.
4. N. Auersperg, J. Pan, B.D. Grove, T. Peterson, J. Fisher, S. Maines-Bandiera, A. Somasiri, and C.D. Roskelley E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium Proc. Natl. Acad. Sci. U.S.A. 96 1999 6249 6254
5. N. Auersperg, C.H. Siemens, and S.E. Myrdal Human ovarian surface epithelium in primary culture In Vitro 20 1984 743 755
6. N. Auersperg, A.S. Wong, K.C. Choi, S.K. Kang, and P.C. Leung Ovarian surface epithelium: biology, endocrinology, and pathology Endocr. Rev. 22 2001 255 288
7. F. Behbod, and J.M. Rosen Will cancer stem cells provide new therapeutic targets? Carcinogenesis 26 2005 703 711
8. R.N. Buick, R. Pullano, and J.M. Trent Comparative properties of five human ovarian adenocarcinoma cell lines Cancer Res. 45 1985 3668 3676
9. M.F. Burbridge, L. Kraus-Berthier, M. Naze, A. Pierre, G. Atassi, and N. Guilbaud Biological and pharmacological characterisation of three models of human ovarian carcinoma established in nude mice: use of the CA125 tumour marker to predict antitumour activity Int. J. Oncol. 15 1999 1155 1162
10. I. Chatzistamou, A.V. Schally, A. Pafiti, H. Kiaris, and H. Koutselini Expression of growth hormone-releasing hormone in human primary endometrial carcinomas Eur. J. Endocrinol. 147 2002 381 386
11. T.R. Chaudhuri, J.M. Mountz, B.E. Rogers, E.E. Partridge, and K.R. Zinn Light-based imaging of green fluorescent protein-positive ovarian cancer xenografts during therapy Gynecol. Oncol. 82 2001 581 589
12. D.C. Connolly, R. Bao, A.Y. Nikitin, K.C. Stephens, T.W. Poole, X. Hua, S.S. Harris, B.C. Vanderhyden, and T.C. Hamilton Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer Cancer Res. 63 2003 1389 1397
13. M. Cuatrecasas, A. Villanueva, X. Matias-Guiu, and J. Prat K-ras mutations in mucinous ovarian tumors: a clinicopathologic and molecular study of 95 cases Cancer 79 1997 1581 1586
14. D. Cvetkovic, D. Pisarcik, C. Lee, T.C. Hamilton, and A. Abdollahi Altered expression and loss of heterozygosity of the LOT1 gene in ovarian cancer Gynecol. Oncol. 95 2004 449 455
15. B.R. Davies, I.A. Steele, R.J. Edmondson, S.A. Zwolinski, G. Saretzki, Z.T. von, and M.J. O'Hare Immortalisation of human ovarian surface epithelium with telomerase and temperature-sensitive SV40 large T antigen Exp. Cell Res. 288 2003 390 402
16. D.M. Dinulescu, T.A. Ince, B.J. Quade, S.A. Shafer, D. Crowley, and T. Jacks Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer Nat. Med. 11 2005 63 70
17. A. Flesken-Nikitin, K.C. Choi, J.P. Eng, E.N. Shmidt, and A.Y. Nikitin Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium Cancer Res. 63 2003 3459 3463
18. K. Garson, E. Macdonald, M. Dube, R. Bao, T.C. Hamilton, and B.C. Vanderhyden Generation of tumors in transgenic mice expressing the SV40 T antigen under the control of ovarian-specific promoter 1 J. Soc. Gynecol. Invest. 10 2003 244 250
19. A.K. Godwin, J.R. Testa, L.M. Handel, Z. Liu, L.A. Vanderveer, P.A. Tracey, and T.C. Hamilton Spontaneous transformation of rat ovarian surface epithelial cells: association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancer J. Natl. Cancer Inst. 84 1992 592 601
20. A. Gossmann, T.H. Helbich, S. Mesiano, D.M. Shames, M.F. Wendland, T.P. Roberts, N. Ferrara, R.B. Jaffe, and R.C. Brasch Magnetic resonance imaging in an experimental model of human ovarian cancer demonstrating altered microvascular permeability after inhibition of vascular endothelial growth factor Am. J. Obstet. Gynecol. 183 2000 956 963
21. L. Gregoire, A. Munkarah, R. Rabah, R.T. Morris, and W.D. Lancaster Organotypic culture of human ovarian surface epithelial cells: a potential model for ovarian carcinogenesis In Vitro Cell Dev. Biol. Anim. 34 1998 636 639
22. W.C. Hahn, and R.A. Weinberg Modelling the molecular circuitry of cancer Nat. Rev. Cancer 2 2002 331 341
23. N.M. Hamad, J.H. Elconin, A.E. Karnoub, W. Bai, J.N. Rich, R.T. Abraham, C.J. Der, and C.M. Counter Distinct requirements for Ras oncogenesis in human versus mouse cells Genes Dev. 16 2002 2045 2057
24. A.G. Hoffman, R.C. Burghardt, R. Tilley, and N. Auersperg An in vitro model of ovarian epithelial carcinogenesis: changes in cell-cell communication and adhesion occuring during neoplastic progression Int. J. Cancer 54 1993 828 838
25. M. Kido, and M. Shibuya Isolation and characterization of mouse ovarian surface epithelial cell lines Pathol. Res. Pract. 194 1998 725 730
26. F. Kraeber-Bodere, A. Mishra, P. Thedrez, A. Faivre-Chauvet, M. Bardies, S. Imai, J. Le Boterff, and J.F. Chatal Pharmacokinetics and biodistribution of samarium-153-labelled OC125 antibody coupled to CITCDTPA in a xenograft model of ovarian cancer Eur. J. Nucl. Med. 23 1996 560 567
27. T. Kusakari, M. Kariya, M. Mandai, Y. Tsuruta, A.A. Hamid, K. Fukuhara, K. Nanbu, K. Takakura, and S. Fujii C-erbB-2 or mutant Ha-ras induced malignant transformation of immortalized human ovarian surface epithelial cells in vitro Br. J. Cancer 89 2003 2293 2298
28. J. Liu, G. Yang, J.A. Thompson-Lanza, A. Glassman, K. Hayes, A. Patterson, R.T. Marquez, N. Auersperg, Y. Yu, W.C. Hahn, G.B. Mills, and R.C. Bast Jr. A genetically defined model for human ovarian cancer Cancer Res. 64 2004 1655 1663
29. P.T. Masiakos, D.T. MacLaughlin, S. Maheswaran, J. Teixeira, A.F. Fuller Jr., P.C. Shah, D.J. Kehas, M.K. Kenneally, D.M. Dombkowski, T.U. Ha, F.I. Preffer, and P.K. Donahoe Human ovarian cancer, cell lines, and primary ascites cells express the human Mullerian inhibiting substance (MIS) type II receptor, bind, and are responsive to MIS Clin. Cancer Res. 5 1999 3488 3499
30. R. Meuwissen, J. Jonkers, and A. Berns Mouse models for sporadic cancer Exp. Cell Res. 264 2001 100 110
31. B.J. Milner, L.A. Allan, D.M. Eccles, H.C. Kitchener, R.C. Leonard, K.F. Kelly, D.E. Parkin, and N.E. Haites p53 Mutation is a common genetic event in ovarian carcinoma Cancer Res. 53 1993 2128 2132
32. V. Mobus, C.D. Gerharz, U. Press, R. Moll, T. Beck, W. Mellin, K. Pollow, P.G. Knapstein, and R. Kreienberg Morphological, immunohistochemical and biochemical characterization of 6 newly established human ovarian carcinoma cell lines Int. J. Cancer 52 1992 76 84
33. C.F. Molthoff, J.J. Calame, H.M. Pinedo, and E. Boven Human ovarian cancer xenografts in nude mice: characterization and analysis of antigen expression Int. J. Cancer 47 1991 72 79
34. E.E. Nilsson, S.D. Westfall, C. McDonald, T. Lison, I. Sadler-Riggleman, and M.K. Skinner An in vivo mouse reporter gene (human secreted alkaline phosphatase) model to monitor ovarian tumor growth and response to therapeutics Cancer Chemother. Pharmacol. 49 2002 93 100
35. M. Nitta, H. Katabuchi, H. Ohtake, H. Tashiro, M. Yamaizumi, and H. Okamura Characterization and tumorigenicity of human ovarian surface epithelial cells immortalized by SV40 large T antigen Gynecol. Oncol. 81 2001 10 17
36. K. Obata, S.J. Morland, R.H. Watson, A. Hitchcock, G. Chenevix-Trench, E.J. Thomas, and I.G. Campbell Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors Cancer Res. 58 1998 2095 2097
37. S. Orsulic, Y. Li, R.A. Soslow, L.A. Vitale-Cross, J.S. Gutkind, and H.E. Varmus Induction of ovarian cancer by defined multiple genetic changes in a mouse model system Cancer Cell 1 2002 53 62
38. K.F. Roby, C.C. Taylor, J.P. Sweetwood, Y. Cheng, J.L. Pace, O. Tawfik, D.L. Persons, P.G. Smith, and P.F. Terranova Development of a syngeneic mouse model for events related to ovarian cancer Carcinogenesis 21 2000 585 591
39. J. Rygaard, and C.O. Povlsen Heterotransplantation of a human malignant tumour to "Nude" mice Acta Pathol. Microbiol. Scand. 77 1969 758 760
40. B. Sauer Inducible gene targeting in mice using the Cre/lox system Methods 14 1998 381 392
41. R.E. Scully Pathology of ovarian cancer precursors J. Cell Biochem. 23 Suppl. 1995 208 218
42. M. Selvakumaran, R. Bao, A.P. Crijns, D.C. Connolly, J.K. Weinstein, and T.C. Hamilton Ovarian epithelial cell lineage-specific gene expression using the promoter of a retrovirus-like element Cancer Res. 61 2001 1291 1295
43. T.J. Shaw, M.K. Senterman, K. Dawson, C.A. Crane, and B.C. Vanderhyden Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer Mol. Ther. 10 2004 1032 1042
44. C.J. Sherr, and F. McCormick The RB and p53 pathways in cancer Cancer Cell 2 2002 103 112
45. C.S. Sullivan, and J.M. Pipas T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis Microbiol. Mol. Biol. Rev. 66 2002 179 202
46. J.R. Testa, L.A. Getts, H. Salazar, Z. Liu, L.M. Handel, A.K. Godwin, and T.C. Hamilton Spontaneous transformation of rat ovarian surface epithelial cells results in well to poorly differentiated tumors with a parallel range of cytogenetic complexity Cancer Res. 54 1994 2778 2784
47. S.W. Tsao, S.C. Mok, E.G. Fey, J.A. Fletcher, T.S. Wan, E.C. Chew, M.G. Muto, R.C. Knapp, and R.S. Berkowitz Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs) Exp. Cell Res. 218 1995 499 507
48. S. Tsukagoshi, Y. Saga, N. Suzuki, A. Fujioka, F. Nakagawa, M. Fukushima, and M. Suzuki Thymidine phosphorylase-mediated angiogenesis regulated by thymidine phosphorylase inhibitor in human ovarian cancer cells in vivo Int. J. Oncol. 22 2003 961 967
49. X. Xu, K.U. Wagner, D. Larson, Z. Weaver, C. Li, T. Ried, L. Hennighausen, A. Wynshaw-Boris, and C.X. Deng Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation Nat. Genet. 22 1999 37 43
50. G. Yang, J.A. Thompson, B. Fang, and J. Liu Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumor growth in a model of human ovarian cancer Oncogene 22 2003 5694 5701
51. K.K. Zorn, A.A. Jazaeri, C.S. Awtrey, G.J. Gardner, S.C. Mok, J. Boyd, and M.J. Birrer Choice of normal ovarian control influences determination of differentially expressed genes in ovarian cancer expression profiling studies Clin. Cancer Res. 9 2003 4811 4818