Heterogenous nuclear ribonucleoprotein F modulates angiotensinogen gene expression in rat kidney proximal tubular cells

Journal of the American Society of Nephrology

Volumn 16, Issue 3, 2005, Pages 616-628

  Wei, Chih Chang ^a   Guo, Deng Fu ^a   Zhang, Shao Ling ^b   Ingelfinger, Julie R ^b   Chan, John S D ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSINOGEN; BINDING PROTEIN; COMPLEMENTARY DNA; DNA FRAGMENT; GLUCOSE; GLUTATHIONE TRANSFERASE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; INSULIN; NUCLEAR CAP BINDING PROTEIN; NUCLEAR PROTEIN; POLYCLONAL ANTIBODY; RECOMBINANT PROTEIN; RNA POLYMERASE II; ANTIDIABETIC AGENT; IRON REGULATORY FACTOR; MESSENGER RNA;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN; GEL MOBILITY SHIFT ASSAY; GENE ACTIVITY; GENE EXPRESSION; GENE IDENTIFICATION; KIDNEY TUBULE CELL; LUNG; MASS SPECTROMETRY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHWESTERN BLOTTING; TESTIS; TISSUE DISTRIBUTION; TWO DIMENSIONAL ELECTROPHORESIS; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; KIDNEY PROXIMAL TUBULE; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROMOTER REGION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

AMINO ACID SEQUENCE; ANGIOTENSINOGEN; ANIMALS; CELLS, CULTURED; CLONING, MOLECULAR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION REGULATION; GLUCOSE; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP F-H; HYPOGLYCEMIC AGENTS; INSULIN; IRON-REGULATORY PROTEINS; KIDNEY TUBULES, PROXIMAL; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RATS; RNA, MESSENGER;

EID: 20544459413     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2004080715     Document Type: Article

References (58)

1. O'Brien RM, Granner DK: Regulation of gene expression by insulin. Physiol Rev 76: 1109-1161, 1996
2. O'Brien RM, Streeper RS, Ayala JE, Stademaier BT, Hornbuckle LA: Insulin-regulated gene expression. Biochem Soc Trans 29: 552-558, 2001
3. O'Brien RM, Lucas PC, Forest CD, Maguson MA, Granner DK: Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription. Science 249: 533-537, 1990
4. Suwanichkul A, Morris SL, Powell DR: Identification of an insulin-responsive element in the promoter of the human gene for insulin-like growth factor binding protein-1. J Biol Chem 268: 17063-17068, 1993
5. Ganss R, Weih F, Schutz G: The cyclic adenosine 3′, 5′-monophosphate- and the glucocorticoid-dependent enhances are targets for insulin repression of tyrosine aminotransferase gene transcription. Mol Endocrinol 8: 895-903, 1994
6. Streeper RS, Svitek CA, Chapman S, Greenbaum LE, Taub R, O'Brien RM: A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin. J Biol Chem 272: 11698-11701, 1997
7. Chen M, Breslow JL, Li W, Leff T: Transcriptional regulation of the apoC-III gene by insulin in diabetic mice: Correlation with changes in plasma triglycerides levels. J Lipid Res 35: 1918-1924, 1994
8. Beurton F, Bandyopadhyay U, Dieumegard B, Barouki R, Aggerbeck M: Delineation of the insulin-responsive sequence in the rat cytosolic aspartate amino-transferase gene: Binding sites for hepatocyte nuclear factor-3 and nuclear factor-1. Biochem J 343: 687-695, 1999
9. Ohkubo H, Kageyama R, Ujihara M, Hirose T, Inayama S, Nakanishi S: Cloning and sequence analysis of cDNA for rat angiotensinogen. Proc Natl Acad U S A 80: 2196-2200, 1983
10. Kageyama R, Ohkubo H, Nakanishi S: Primary structure of human pre-angiotensinogen deuced from the cloned cDNA sequence. Biochemistry 23: 3603-3609, 1984
11. Dzau VJ, Ingelfinger JR: Molecular biology and pathophysiology of the intrarenal renin-angiotensin system. J Hypertens 7[Suppl 7]: 53-58, 1989
12. Johnston CI, Fabris B, Jandeleit K: Intrarenal renin-angiotensin system in renal physiology and pathophysiology. Kidney Int 44[Suppl 42]: 559-563, 1993
13. Ingelfinger JR, Zuo WM, Fon EA, Ellison KE, Dzau VJ: In situ hybridization evidence for angiotensinogen mRNA in the rat proximal tubule. A hypothesis for the intrarenal renin-angiotensin system. J Clin Invest 85: 417-423, 1990
14. Wolf G, Neilson EG: Angiotensin II as a hypertrophogenic cytokine for proximal tubular cells. Kidney Int 43[Suppl 39]: S100-S107, 1992
15. 1 angiotensin II receptor that is present in proximal tubule epithelium. Am J Physiol 264: F645-F654, 1993
16. Anderson S, Jung FF, Ingelfinger JR: Renal renin-angiotensin system in diabetes: Functional, immunohistochemical, and molecular biological corrections. Am J Physiol 265: F477-F486, 1993
17. Tang SS, Jung F, Diamant D, Brown D, Bachinsky D, Hellman P, Ingelfinger J: Temperature-sensitive SV 40 immortalized rat proximal tubule cell line has functional reninangiotensin system. Am J Physiol 268: F435-F446, 1995
18. Loghman-Adham M, Rohrwasser A, Helin C, Zhang S, Terreros D, Inoue I, Lalouel J-M: A conditionally immortalized cell line from murine proximal tubule. Kidney Int 52: 229-239, 1997
19. Chen M, Harris MP, Rose D, Smart A, He XR, Kretyler M, Briggs JP, Schnermann J: Renin and renin mRNA in proximal tubule of the rat kidney. J Clin Invest 94: 237-243, 1994
20. Wang L, Lei C, Zhang S-L, Roberts KD, Tang S-S, Ingelfinger JR, Chan JSD: Synergistic effect of dexamethasone and isoproterenol on the expression of angiotensinogen in immortalized rat proximal tubular cells. Kidney Int 53: 287-295, 1998
21. Lai KN, Leung JCK, Lai KB, To WY, Yeung VT, Lai FM-M: Gene expression of the renin-angiotensin system in human kidney. J Hypertens 16: 91-102, 1998
22. Zimpelmann J, Kumar D, Levine DZ, Wehbi G, Imig JD, Navar LG, Burns KD: Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat kidney. Kidney Int 58: 2320-2330, 2000
23. Zhang S-L, Filep JG, Hohman TC, Tang S-S, Ingelfinger JR, Chan JSD: Molecular mechanisms(s) of glucose action on angiotensinogen gene expression in rat proximal tubular cells. Kidney Int 55: 454-464, 1999
24. Zhang S-L, Tang S-S, Chen X, Filep JG, Ingelfinger JR, Chan JSD: High levels of glucose stimulate angiotensinogen gene expression via the p38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells. Endocrinology 141: 4637-4646, 2000
25. Hsieh T-J, Zhang S-L, Filep JG, Tang S-S, Ingelfinger JR, Chan JSD: High glucose stimulates angiotensinogen gene expression via reactive oxygen species (ROS) generation in rat kidney proximal tubular cells. Endocrinology 143: 2975-2985, 2002
26. Hsieh T-J, Fustier P, Zhang S-L, Filep JG, Tang S-S, Ingelfinger JR, Fantus IG, Hamet P, Chan JSD: High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of hexosamine biosynthesis pathway in rat kidney proximal tubular cells. Endocrinology 144: 4338-4349, 2003
27. Zhang S-L, To C, Chen X, Filep JG, Tang S-S, Ingelfinger JR, Carrière S, Chan JSD: Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells. Exp Nephrol 9: 109-117, 2001
28. Zhang S-L, Hsieh T-J, Chen X, Filep JG, Tang S-S, Ingelfinger JR, Chan JSD: Essential role(s) of intrarenal reninangiotensin system on transforming growth factor-β 1 expression and induction of hypertrophy in rat kidney proximal tubular cells in high glucose. J Am Soc Nephrol 13: 302-312, 2002
29. Zhang S-L, Chen X, Filep JG, Tang S-S, Ingelfinger JR, Chan JSD: Insulin inhibits angiotensinogen gene expression via the mitogen-activated protein kinase pathway in rat kidney proximal tubular cells. Endocrinology 140: 5285-5292, 1999
30. Zhang S-L, Chen X, Wei C-C, Filep JG, Tang S-S, Ingelfinger JR, Chan JSD: Insulin inhibits dexamethasone effect on angiotensinogen gene expression and induction of hypertrophy in rat kidney proximal tubular cells in high glucose. Endocrinology 143: 4627-4635, 2002
31. Chen X, Zhang S-L, Pang L, Filep JG, Tang S-S, Ingelfinger JR, Chan JSD: Characterization of a putative insulin-responsive element and its binding protein(s) in rat angiotensinogen gene promoter: Regulation by glucose and insulin. Endocrinology 142: 2577-2585, 2001
32. Chan JSD, Chan AHH, Jiang M, Nie Z-R, Lachance S, Carrière S: Molecular cloning and expression of the rat angiotensinogen gene. Pediatr Nephrol 4: 429-435, 1990
33. Matunis MJ, Xing J, Dreyfus G: The hnRNP F protein: Unique primary structure, nucleic acid-binding properties, and subcellular localization. Nucl Acids Res 22: 1057-1067, 1994
34. Yoshida T, Kokura K, Makino Y, Ossipow V, Tamura T: Heterogenous nuclear RNA-ribonucleoprotein F binds to DNA via an oligo (dG)-motif and is associated with RNA polymerase II. Genes Cells 4: 707-719, 1999
35. o to S phase transition. Proc Natl Acad Sci U S A 95: 11095-11100, 1998
36. Nasrin N, Ercolani L, Denaro M, Kong XF, Kang I, Alexander M: An insulin responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene binds a nuclear protein induced by insulin in cultured cells and by nutritional manipulations in vitro. Proc Natl Acad Sci U S A 87: 5273-5277, 1990
37. Philippe J: Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element. Proc Natl Acad Sci U S A 88: 7224-7227, 1991
38. Dynan WS, Tjian R: The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell 35: 79-87, 1983
39. Ingelfinger JR, Jung F, Diamant D, Haveran L, Lee E, Brem A, Tang SS: Rat proximal tubule cell line transformed with origin-defective SV40 DNA: Autocrine Ang II feedback. Am J Physiol 276: F218-F227, 1999
40. Henninghausen L, Lubon H: Interaction of protein with DNA in vitro. Methods Enzymol 4: 429-435, 1987
41. Wu J, Jiang Q, Chen X, Wu X-H, Chan JSD: Identification of a novel mouse hepatic 52 kDa protein that interacts with the cAMP response element of the rat angiotensinogen gene. Biochem J 329: 623-629, 1998
42. Kwast-Welfeld J, de Belle I, Walker PR, Whitfield JF, Sikorska M: Identification of new cAMP response element-binding factor by Southwestern blotting. J Biol Chem 268: 19581-19585, 1993
43. 4. Nature 227: 680-685, 1970
44. Nudel U, Zakut R, Shani M, Neuman S, Levy Z, Yaffe D: The nucleotide sequence of the rat cytoplasmic β-acting gene. Nucleic Acids Res 11: 1759-1771, 1983
45. Dreyfuss G, Matunis MJ, Pinol-Roma S, Burd CG: HnRNP proteins and the biogenesis of mRNA. Annu Res Cell Biol 62: 289-321, 1993
46. Krecic AM, Swanson MS: HnRNP complexes: Composition, structure, and function. Curr Opin Cell Biol 11: 363-371, 1999
47. Choi YD, Grabowski PJ, Shrp PA, Dreyfuss G: Heterogeneous nuclear ribonucleoproteins: Role in RNA splicing. Science 231: 1534-1539, 1986
48. Sierakowska H, Szea W, Furdon PJ, Kole R: Antibodies to hnRNP core proteins inhibit in vitro splicing of human β globin pre-mRNA. Nucleic Acids Res 14: 5241-5254, 1986
49. Gattoni R, Mahe D, Mahl P, Fischer N, Mattel MG, Stevenin J, Fuchs JP: The human hnRNP-M proteins: Structure and relation with early heat shock-induced splicing arrest and chromosome mapping. Nucleic Acids Res 24: 2535-2542, 1996
50. Honore B, Rasmussen HH, Vorum H, Dejgarrd K, Liu X, Gromov P, Madsen P, Gesser B, Tommerup N, Celis JE: Heterogeneous nuclear ribonucleoproteins H, H′, and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes. J Biol Chem 270: 28780-28789, 1995
51. Min H, Chan RC, Black DL: The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event. Genes Dev 9: 2659-2671, 1995
52. Chen CD, Kobayashi R, Helfman DM: Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat tropomyosin gene. Genes Dev 13: 593-606, 1999
53. Hastings ML, Wilson CM, Munroe SH: A purine-rich intronic element enhances alternative splicing of thyroid hormone receptor mRNA. RNA 7: 859-874, 2001
54. Veraldi KL, Arhin GK, Martincic K, Chung-Ganster LH, Wilusz J, Milcarek C: hnRNP F influences binding of a 64-kilodalton subunit of cleavage stimulation factor to mRNA precursors in mouse B cells. Mol Cell Biol 21: 1228-1238, 2001
55. Yoshida T, Makino Y, Tamura T: Association of the rat heterogeneous nuclear RNA-ribonucleoprotein F with TATA-binding protein. FEBS Lett 457: 251-254, 1999
56. Gamberi C, Izaurralde E, Beisel C, Mattaj IW: Interaction between the human nuclear cap-binding protein complex and hnRNP F. Mol Cell Biol 17: 2587-2597, 1997
57. Ohkubo H, Nakayama K, Tanaka T, Nakanishi S: Tissue distribution of rat angiotensinogen mRNA and structural analysis of its heterogeneity. J Biol Chem 261: 319-323, 1986
58. Leung PS, Wong TP, Sernia C: Angiotensinogen expression by rat epididymis: Evidence for an intrinsic angiotensin-generating system. Mol Cell Endocrinol 155: 115-122, 1999