The effect of risedronate on bone mineralization as measured by micro-computed tomography with synchrotron radiation: Correlation to histomorphometric indices of turnover

Bone

Volumn 37, Issue 1, 2005, Pages 1-9

  Borah, Babul ^a   Ritman, Erik L ^b   Dufresne, Thomas E ^a   Jorgensen, Steven M ^b   Liu, Sheng ^a   Sacha, Jarek ^a   Phipps, Roger J ^a   Turner, Russell T ^c  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^b MAYO CLINIC   (United States)

^c OREGON STATE UNIVERSITY   (United States)

Author keywords

Bone turnover; Mineralization; Osteoporosis; Risedronate; Synchrotron

Indexed keywords

PLACEBO; RISEDRONIC ACID;

ARTICLE; BONE BIOPSY; BONE MINERAL; BONE MINERALIZATION; BONE TURNOVER; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG DETERMINATION; FEMALE; HUMAN; HUMAN TISSUE; ILIAC BONE; MEDICAL ASSESSMENT; MORPHOMETRICS; OSSIFICATION; POSTMENOPAUSE; POSTMENOPAUSE OSTEOPOROSIS; SYNCHROTRON RADIATION; TRABECULAR BONE;

AGED; BIOPSY; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; CALCIFICATION, PHYSIOLOGIC; DATA INTERPRETATION, STATISTICAL; ETIDRONIC ACID; FEMALE; HUMANS; ILIUM; LUMBAR VERTEBRAE; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; SYNCHROTRONS; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 20544449394     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.03.017     Document Type: Article

References (41)

1. P. Garnero, E. Hausherr, M.C. Chapuy, C. Marcelli, H. Grandjean, and C. Muller Markers of bone resorption predict hip fracture in elderly women: the EPIDOS prospective study J. Bone Miner. Res. 11 1996 (Oct) 1531 1538
2. B.L. Riggs, and J.L. Melton III Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density J. Bone Miner. Res. 17 2002 11 14
3. R.P. Heaney Is the paradigm shifting? Bone 33 2003 457 465
4. L.J. Melton III, S. Khosla, E.J. Atkinson, W.M. O'Fallon, and B.L. Riggs Relationship of bone turnover to bone density and fractures J. Bone Miner. Res. 12 1997 1083 1091
5. C.H. Chestnut III, and C.J. Rosen Bone quality discussion group. Reconsidering the effects of antiresorptive therapies in reducing osteoporotic fracture J. Bone Miner. Res. 16 2001 2163 2172
6. C.H. Turner Biomechanics of bone: determinants of skeletal fragility and bone quality Osteoporos Int. 13 2002 97 104
7. S.T. Harris, N.B. Watts, H.K. Genant, C.D. McKeever, T. Hangartner, and M. Keller for the Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial JAMA 282 1999 1344 1352
8. J.-Y. Reginster, H.W. Minne, O.H Sorensen, M. Hooper, C. Roux, M.L. Brandi on behalf of the Vertebral Efficacy with Risedronate Therapy (VERT) Study Group Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis Osteoporos Int. 11 2000 83 91
9. D.M. Reid, R.A. Hughes, R.F. Laan, N.A. Sacco-Gibson, D.H. Wenderoth, and S. Adami Efficacy and safety of daily risedronate in the treatment of corticosteroid-induced osteoporosis in men and women: a randomized trial. European corticosteroid-induced osteoporosis treatment study J. Bone Miner. Res. 15 2000 1006 1013
10. S. Cohen, R.M. Levy, M. Keller, E. Boling, R.D. Emkey, and M. Greenwald Risedronate therapy prevents corticosteroid-induced bone loss: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, parallel group study Arthritis Rheum. 42 1999 2309 2318
11. R. Eastell, I. Barton, R.A. Hannon, A. Chines, P. Garnero, and P.D. Delmas Relationship of early changes in bone resorption to the reduction of fracture risk with risedronate J. Bone Miner. 18 2003 1051 1056
12. T.E. Dufresne, P.A. Chmielewski, M.D. Manhart, T.D. Johnson, and B. Borah Risedronate preserves bone architecture in early postmenopausal women in 1 year as measured by three-dimensional microcomputed tomography Calcif. Tissue Int. 73 2003 423 432
13. B. Borah, T.E. Dufresne, P.A. Chmielewski, T.D. Johnson, A. Chines, and M.D. Manhart Risedronate preserves bone architecture in postmenopausal women with osteoporosis as measured by three-dimensional microcomputed tomography Bone 34 2004 736 746
14. T.E. Ciarelli, D.P. Fyhrie, and A.M. Parfitt Effects of vertebral bone fragility and bone formation rate on the mineralization levels of cancellous bone from white females Bone 32 2003 311 315
15. H. Follet, G. Boivin, C. Rumelhart, and P.J. Meunier The degree of mineralization is a determinant of bone strength: a study of human calcanei Bone 34 2004 783 789
16. G. Boivin, and P.J. Meunier Changes in bone remodeling rate influence the degree of mineralization of bone Connect. Tissue Res. 43 2002 535 537
17. P.J. Meunier, and G. Boivin Bone mineral density reflects bone mass but also the degree of mineralization of bone: therapeutic implications Bone 21 1997 373 377
18. J.D. Currey Effects of differences in mineralization on the mechanical properties of bone Philos. Trans. R. Soc. London, B Biol. Sci. 304 1984 509 518
19. J.D. Currey The role of collagen and other organics in the mechanical properties of bone Osteoporos Int. 14 Suppl 5 2003 S29 S36
20. S. Nuzzo, M.H. Lafage-Proust, E. Martin-Badosa, G. Boivin, T. Thomas, and C. Alexandre Synchrotron radiation microtomography allows the analysis of three-dimensional microarchitecture and degree of mineralization of human iliac crest biopsy specimens: effects of etidronate treatment J. Bone Miner. Res. 17 2002 1372 1382
21. E.L. Ritman, S.M. Jorgensen, P.E. Lund, P.J. Thomas, J.H. Dunsmuir, and J.C. Romero Synchrotron-based micro-CT of in situ biological basic functional units and their integration SPIE 3149 1977 13 24
22. E.L. Ritman, M.E. Bolander, L.A. Fitzpatrick, and R.T. Turner Micro-CT imaging of structure-to-function relationship of bone microstructure and associated vascular involvement Technol. Health Care 6 1998 403 412
23. K. Engelke, W. Graeff, L. Meiss, M. Hahn, and G. Delling High spatial resolution imaging of bone mineral using computed microtomography. Comparison with microradiography and undecalcified histologic sections Invest. Radiol. 28 1993 341 349
24. E.F. Eriksen, F. Melsen, E. Sod, I. Barton, and A. Chines Effects of long-term risedronate on bone quality and bone turnover in women with postmenopausal osteoporosis Bone 31 2002 620 625
25. E.R. Weibel Estimation of basic stereological parameters Stereological methods vol. 2 1989 Academic Press London 55 104
26. A.M. Parfitt The physiologic and clinical significance of bone histomorphometric data R.R. Recker Bone Histomorphometry: Techniques and Interpretation 1983 CRC Press Boca Raton, FL 143 223
27. G. Marotti, A. Favia, and A.Z. Zallone Quantitative analysis on the rate of secondary mineralization Calcif. Tissue Res. 10 1972 67 81
28. R. Lindsay, S. Boonen, D. Burgio, T. Johnson, A. Grauer, and P. Miller Significant reduction of bone resorption with risedronate treatment as soon as one week J. Bone Miner. Res. 19 Suppl 1 2004 SU 434
29. A.M. Parfitt, and H. Duncan Metabolic bone disease affecting the spine R. Rothman F. Simeone The Spine 2nd ed. 1982 WB Saunders Philadelphia 775 905
30. G.Y. Boivin, P.M. Chavassieux, A.C. Santora, J. Yates, and P.J. Meunier Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women Bone 27 2000 687 694
31. T.E. Dufresne, P.A. Chmielewski, and B. Borah A novel method for the measurement of degree of mineralization using bench-top μCT J. Bone Miner. Res. 18 S2 2003 S319
32. E.L. Ritman Micro-computed tomography-Current status and developments Annu. Rev. Biomed. Eng. 6 2004 185 208
33. P. Roschger, S. Rinnerthaler, J. Yates, G.A. Rodan, P. Fratzl, and K. Klaushofer Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic women Bone 29 2001 185 191
34. G. Boivin, and P.J. Meunier Inter-individual heterogeneity index of mineralization is an important determinant of quality of bone J. Bone Miner. Res. 19 S1 2004 S114
35. B. Borah, E.L. Ritman, T.E. Dufresne, S. Liu, P.A. Chmielewski, and S.M. Jorgensen Five year risedronate therapy normalizes mineralization: synchrotron radiation micro-computed tomography study of sequential triple biopsies J. Bone Miner. Res. 19 S1 2004 S308
36. O.H. Sorensen, G.M. Crawford, H. Mulder, D.J. Hosking, C. Gennari, and D. Mellstrom Long-term efficacy of risedronate: a 5-year placebo-controlled clinical experience Bone 32 2003 120 126
37. O. Sorensen, S. Goemare, D. Wenderoth, A. Chines, and C. Roux Sustained effect of risedronate: a 7-year study in postmenopausal women [abstract] Calcif. Tissue Int. 72 2003 402
38. A. Oleksik, S.M. Ott, S. Vedi, N. Bravenboer, J. Compston, and P. Lips Bone structure in patients with low bone mineral density with or without vertebral fractures J. Bone Miner. Res. 15 2000 1368 1375
39. L. Mosekilde, A. Viidik, and L. Mosekilde Correlation between the compressive strength of iliac and vertebral trabecular bone in normal individuals Bone 6 5 1985 291 295
40. J. Podenphant, A. Gotfredsen, L. Nilas, H. Norgaard, and O. Braendstrup Iliac crest biopsy: representivity for the amount of mineralized bone Bone 7 1986 427 430
41. R.A. Hannon, R.L. Licence, A.A. Chines, E.W. Sod, E.F. Eriksen, and R. Eastell Decrease in bone resorption markers in response to risedronate: relationship to decrease in estimates of bone turnover using bone histomorphometry J. Bone Miner. Res. 17 2002 S270