Synthesis of 2-methyl-4-methoxydiphenylamine by palladium catalyzed C-N coupling - High synthetic versatility by use of a flexible catalytic system

Tetrahedron

Volumn 61, Issue 26, 2005, Pages 6379-6385

  Scholz, Ulrich ^a   Schlummer, Björn ^a  

^a LANXESS DEUTSCHLAND GMBH   (Germany)

Author keywords

Buchwald Hartwig Amination; Diarylamines; Homogeneous catalysis; Palladium

Indexed keywords

2 METHYL 4 METHOXYDIPHENYLAMINE; ANILINE DERIVATIVE; AROMATIC AMINE; LIGAND; PALLADIUM; SOLVENT; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 20444470741     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2005.03.139     Document Type: Article

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32. Since the use of ligand 7 is protected by Watanabe et al., Tosoh Corp. (EP 0 802 173, 1996) we chose not to pursue this result for further optimization. On the other hand Lanxess has licensed Buchwald's ligands, which are protected by WO 00/028887 and therefore is free to use them.