Synthesis of new phorbol derivatives having ethereal side chain and evaluation of their anti-HIV activity

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 14, 2005, Pages 4383-4388

  Matsuya, Yuji ^a   Yu, Zhong ^b   Yamamoto, Naoki ^b   Mori, Masao ^c   Saito, Haruo ^c   Takeuchi, Makoto ^c   Ito, Mamiko ^c   Nemoto, Hideo ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c Lead Chemical Co Ltd   (Japan)

Author keywords

Anti HIV agents; Ethereal side chain; Phorbol; Safety index

Indexed keywords

12 O ETHYL 20 O (TERT BUTYLDIMETHYLSILYL)PHORBOL 13 DECANOATE; 12 O METHOXYMETHYL 20 O METHYLPHORBOL 13 DECANOATE; PHORBOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG INHIBITION; DRUG POTENCY; DRUG SAFETY; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INCUBATION TIME; MALE; MOUSE; NITROBLUE TETRAZOLIUM TEST; NONHUMAN;

ANTI-HIV AGENTS; CELL LINE; DRUG EVALUATION, PRECLINICAL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PHORBOLS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 20444455845     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.04.056     Document Type: Article

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