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Volumn 124, Issue 36, 2002, Pages 10658-10659
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Dramatic switching of protein kinase C agonist/antagonist activity by modifying the 12-ester side chain of phorbol esters
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Author keywords
[No Author keywords available]
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Indexed keywords
ALKANOL;
ANTINEOPLASTIC AGENT;
ESTER;
ETHYLENE GLYCOL DERIVATIVE;
PHORBOL 13 ACETATE 12 MYRISTATE;
PHORBOL ESTER DERIVATIVE;
PROTEIN KINASE C;
PROTEIN KINASE C ACTIVATOR;
PROTEIN KINASE C ALPHA;
PROTEIN KINASE C INHIBITOR;
RECOMBINANT ENZYME;
TRITIUM;
WATER;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
BINDING AFFINITY;
BINDING ASSAY;
CELL MEMBRANE;
CELLULAR DISTRIBUTION;
CHEMICAL MODIFICATION;
COMPETITIVE INHIBITION;
COMPLEX FORMATION;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG MECHANISM;
DRUG POTENCY;
DRUG PROTEIN BINDING;
DRUG SYNTHESIS;
ENZYME ACTIVATION;
ENZYME ACTIVITY;
ENZYME BINDING;
ENZYME INHIBITION;
ENZYME SUBSTRATE COMPLEX;
ESTERIFICATION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN CELL;
HYDROPHILICITY;
MEMBRANE BINDING;
PROTEIN DOMAIN;
RIGIDITY;
STRUCTURE ACTIVITY RELATION;
SURFACE CHARGE;
CELL MEMBRANE;
ENZYME ACTIVATION;
ENZYME INHIBITORS;
HELA CELLS;
HUMANS;
PHORBOL ESTERS;
PROTEIN KINASE C;
STRUCTURE-ACTIVITY RELATIONSHIP;
TETRADECANOYLPHORBOL ACETATE;
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EID: 0037063513
PISSN: 00027863
EISSN: None
Source Type: Journal
DOI: 10.1021/ja027048s Document Type: Article |
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Times cited : (30)
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References (16)
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