Anti-HIV-1 phorbol esters from the seeds of Croton tiglium

Phytochemistry

Volumn 53, Issue 4, 2000, Pages 457-464

  El Mekkawy, Sahar ^a   Meselhy, Meselhy R ^a   Nakamura, Norio ^a   Hattori, Masao ^a   Kawahata, Takuya ^b   Otake, Toru ^b  

^a UNIVERSITY OF TOYAMA   (Japan)

^b OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

12 O Acetylphorbol 13 decanoate; Croton tiglium; HIV 1; Phorbol esters; Protein kinase C

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIVIRUS AGENT; CROTON EXTRACT; MEDICINAL PLANT; PHORBOL ESTER; PHORBOL ESTER DERIVATIVE; PROTEIN KINASE C;

ANIMAL; ANTIVIRAL ACTIVITY; ARTICLE; CELL LINE; CHEMISTRY; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG ISOLATION; DRUG POTENCY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; NONHUMAN; PLANT SEED; RAT; SPECTRAL SENSITIVITY; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY; VIRUS INHIBITION;

ANIMALS; ANTI-HIV AGENTS; CELL LINE; CHROMATOGRAPHY, THIN LAYER; CYTOPATHOGENIC EFFECT, VIRAL; ENZYME ACTIVATION; HIV-1; HUMANS; MICE; PHORBOL ESTERS; PLANTS, MEDICINAL; PROTEIN KINASE C; RATS; SEEDS;

ANIMALIA; CROTON; CROTON TIGLIUM; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0034624488     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(99)00556-7     Document Type: Article

References (30)

1. Blumberg P.M. CRC Crit. Rev. Toxicol. 8:1980;153-197.
2. Blumberg P.M. CRC Crit. Rev. Toxicol. 8:1981;199-234.
3. Blumberg P.M. Cancer Research. 48:1988;1-8.
4. Castagna M., Takai Y., Kaibuchi K., Sano K., Kikkawa U., Nishizuka Y. J. Biol. Chem. 257:1982;7847-7851.
5. Che C.-T. Plants as a source of potential antiviral agents. Wagner H., Farnsworth N.R. Economic and Medicinal Plant Research. vol. 5:1991;Academic Press, London, UK.
6. Chowdhury M.I.H., Koyanagi Y., Kobayshi S., Hamamoto Y.H., Yoshiyama T., Yoshida N., Yamamoto N. Virology. 176:1990;126-132.
7. de Chaffoy de Courcelles D., Roevens P., van Belle H. FEBS Lett. 173:1984;389-393.
8. El-Mekkawy S., Meselhy M.R., Kusumoto I.T., Kadota S., Hattori M., Namba T. Chem. Pharm. Bull. 43:1995;641-648.
9. El-Mekkawy S., Meselhy M.R., Nakamura N., Tezuka Y., Hattori M., Kakiuchi N., Shimotohno K., Kawahata T., Otake T. Phytochemistry. 49:1998;1651-1657.
10. Evans F.J., Taylor S.E. Pro-inflammatory tumor-promoting and anti-tumor diterpenes of the plant families Euphorbiaceae and Thymeleaceae. Herz W., Grisebach H., Kirby G.W. Progress in The Organic Chemistry of Natural Products. vol. 44:1983;1-99 Springer-Verlag, New York.
11. Evans F.J., Soper C.J. J. Nat. Prod. 41:1978;193-233.
12. Evans F.J. Toxicon. 16:1978;51-57.
13. Gschwendt M., Hecker E. Z. Krebsforsch. 81:1974;193.
14. Gustafson K.R., Cardellina II J.H., McMahon J.B., Gulakowski R.J., Ishitoya J., Szallasi Z., Lewin N.E., Blumberg P.M., Weislow O.S., Beutler J.A., Buckheit R.W. Jr., Cragg G.M., Cox P.A., Bader J.P., Boyd M.R. J. Med. Chem. 35:1992;1978-1986.
15. Handa S.S., Kinghorn A.D., Cordell G.A., Farnsworth N.R. J. Nat. Prod. 46:1983;123-126.
16. Harada S., Koyanagi Y., Yamamoto N. Science. 229:1985;563-566.
17. Hecker E. Slaga T.J., Sivak A., Boutwell R.K. Carcinogenesis. vol. 2:1978;11-48 Raven Press, New York.
18. Hecker E., Schmidt R. Progress in the Chemistry of Organic Natural Products. 31:1974;377-467.
19. Hecker E. Isolation and characterization of the co-carcinogenic principles from Croton oil. Busch H. Methods of Cancer Research. vol. VI:1971;439-481 Academic Press, London, UK.
20. Kawahata T., Otake T., Mori H., Morimoto M., Ueba N., Kusumoto I.T., El-Mekkawy S., Hattori M., Namba T. J. Trad. Med. 13:1996;59-65.
21. Kupchan S.M., Uchida I., Branfman A.R., Daily R.G., Yu-Fei B. Jr. Science. 191:1976;571-572.
22. Kusumoto I.T., Hattori M. Searching for anti-HIV agents among the traditional medicines. Watanabe H., Shibuya T. Pharmacological Research on Traditional Herbal Medicines. 1999;219-235 Harwood Academic Publishers, Amsterdam.
23. Moriya T., Saito K., Kurita H., Matsumoto K., Otake T., Mori H., Morimoto M., Ueba N., Kunita N. J. Med. Chem. 36:1993;1674-1677.
24. Nasr M., Cradock J., Johnson M. Structure-activity correlations of natural products with anti-HIV activity. Chu C.-K., Cutler H.G. Natural Products as Antiviral Agents. 1992;31-56 Plenum, New York.
25. Ng T.B., Huang B., Fong W.P., Yeung H.W. Life Sciences. 61:1997;933-949.
26. Nishizuka Y. Nature. 308:1984;693-698.
27. Sakata K., Kawazu K., Mitsui T. Agr. Biol. Chem. 35:1971;2113.
28. Schinazi R.F. Progress in the development of natural products for human immunodeficiency viruses infections. Chu C.-K., Cutler H.G. Natural Products as Antiviral Agents. 1992;1-29 Plenum, New York.
29. Taylor S.E., Gafur M.A., Choudhury A.K., Evans F.J. Tetrahedron Lett. 22:1981;3321-3324.
30. Taylor S.E., Williamson E.M., Evans F.J. Phytochemistry. 22:1983;1231-1233.