Synergistic effects of hydrogen peroxide and ethanol on cell viability loss in PC12 cells by increase in mitochondrial permeability transition

Biochemical Pharmacology

Volumn 70, Issue 2, 2005, Pages 317-325

  Chung, Soo Lee ^a   Yun, Jeong Kim ^a   Hyun, Hee Ko ^a   Eun, Sook Han ^a  

^a Chung Ang University   (South Korea)

Author keywords

Cell injury; Ethanol; Hydrogen peroxide; Mitochondrial membrane permeability; PC12 cells

Indexed keywords

2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; ACETYLCYSTEINE; ALCOHOL; CASPASE 3; CATALASE; CYTOCHROME C; GLUTATHIONE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; TRIFLUOPERAZINE;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL DEATH; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME RELEASE; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ETHANOL; HYDROGEN PEROXIDE; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; PC12 CELLS; PERMEABILITY; RATS;

EID: 20444451685     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.04.029     Document Type: Article

References (39)

1. + opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism Biochim Biophys Acta 1453 1999 49 62
2. M. Crompton The mitochondrial permeability transition pore and its role in cell death Biochem J 341 1999 233 249
3. S.B. Berman, and T.G. Hastings Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease J Neurochem 73 1999 1127 1137
4. C.S. Lee, E.S. Han, Y.Y. Jang, J.H. Han, H.W. Ha, and D.E. Kim Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 cells J Neurochem 75 2000 521 531
5. + on membrane permeability in brain mitochondria and cell viability in PC12 cells Neurochem Int 40 2002 361 369
6. J. Lotharius, and K.L. O'Malley The Parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity J Biol Chem 275 2000 38581 38588
7. + on membrane permeability in mitochondria and cell viability in PC12 cells Neurochem Int 43 2003 147 154
8. J. Lotharius, L.L. Dugan, and K.L. O'Malley Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons J Neurosci 19 1999 1284 1293
9. G. Cohen, R. Farooqui, and N. Kesler Parkinson disease: a new link between monoamine oxidase and mitochondrial electron flow Proc Natl Acad Sci USA 94 1997 4890 4894
10. P. Jenner Oxidative stress in Parkinson's disease Ann Neurol 53 Suppl. 3 2003 S26 S38
11. T. Mronga, T. Stahnke, O. Goldbaum, and C. Richter-Landsberg Mitochondrial pathway is involved in hydrogen-peroxide-induced apoptotic cell death of oligodendrocytes Glia 46 2004 446 455
12. C. Cabaner, C. Gajate, A. Macho, E. Munoz, M. Modolell, and F. Mollinedo Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system Br J Pharmacol 127 1999 813 825
13. H. Wang, and J.A. Joseph Mechanisms of hydrogen peroxide-induced calcium dysregulation in PC12 cells Free Radic Biol Med 28 2000 1222 1231
14. M.B. Heaton, I. Madorsky, M. Paiva, and J. Mayer Influence of ethanol on neonatal cerebellum of BDNF gene-deleted animals: analyses of effects on Purkinje cells, apoptosis-related proteins, and endogenous antioxidants J Neurobiol 51 2002 160 176
15. C. Young, B.J. Klocke, T. Tenkova, J. Choi, J. Labruyere, and Y.Q. Qin Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain Cell Death Differ 10 2003 1148 1155
16. J.H. Hoek, and J.G. Pastrino Ethanol, oxidative stress, and cytokine-induced liver cell injury Alcohol 27 2002 63 68
17. M. Pascual, S.L. Valles, J. Renau-Piqueras, and C. Guerri Ceramide pathways modulate ethanol-induced cell death in astrocytes J Neurochem 87 2003 1535 1545
18. E. Agar, M. Bosnak, R. Amanvermez, S. Demir, M. Ayyildiz, and C. Celik The effect of ethanol on lipid peroxidation and glutathione level in the brain stem of rat Neuroreport 10 1999 1799 1801
19. J.G. Pastrino, and J.H. Hoek Ethanol potentiates tumor necrosis factor-α cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition Hepatology 31 2000 1141 1152
20. Y. Rajgopal, C.S. Chetty, and M.C. Vermuri Differential modulation of apoptosis-associated proteins by ethanol in rat cerebral cortex and cerebellum Eur J Pharmacol 470 2003 117 1124
21. J.G. Pastrino, A. Marcineviciute, A. Cahill, and J.H. Hoek Potentiation by chronic ethanol treatment of the mitochondrial permeability transition Biochem Biophys Res Commun 265 1999 405 409
22. W.G. Tatton, R.M.E. Chalmers-Redman, W.J.H. Ju, M. Mammen, G.W. Carlile, and A.W. Pong Propargylamines induce antiapoptotic new protein synthesis in serum-and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells J Pharmacol Exp Ther 301 2002 753 764
23. C-T. Lai, and P.H. Yu R(-)-Deprenyl potentiates dopamine-induced cytotoxicity toward catecholaminergic neuroblastoma SH-SY5Y cells Toxicol Appl Pharmacol 142 1997 186 191
24. T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 1983 55 63
25. F.A. Oberhammer, M. Pavelka, S. Sharma, R. Tiefenbacher, A.F. Purchio, and W. Bursch Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor β1 Proc Natl Acad Sci USA 89 1992 5408 5412
26. J.S. Isenberg, and J.E. Klaunig Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells Toxicol Sci 53 2000 340 351
27. W. Fu, H. Luo, S. Parthasarathy, and M.P. Mattson Catecholamines potentiate amyloid β-peptide neurotoxicity: involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis Neurobiol Dis 5 1998 229 243
28. R.J. van Klaveren, P.H.M. Hoet, J.L. Pype, M. Demedts, and B. Nemery Increase in γ-glutamyltransferase by glutathione depletion in rat type II pneumocytes Free Radic Biol Med 22 1997 525 534
29. J. Chandra, A. Samali, and S. Orrenius Triggering and modulation of apoptosis by oxidative stress Free Radic Biol Med 29 2000 323 333
30. T. Kadota, T. Yamaai, Y. Saito, Y. Akita, S. Kawashima, and K. Moroi Expression of dopamine transporter at the tips of growing neurites of PC12 cells J Histochem Cytochem 44 1996 989 996
31. R.A. Ross, B.A. Spengler, and J.L. Biedler Coordinate morphological and biochemical interconversion of human neuroblastoma cells J Natl Cancer Inst 71 1983 741 749
32. M.B. Spina, S.P. Squinto, J. Miller, R.M. Lindsay, and C. Hyman Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system J Neurochem 59 1992 99 106
33. M.B.H Youdim, T. Amit, M. Falach-Yogev, O.B. Am, W. Maruyama, and M. Naoi The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson's drug, rasagiline Biochem Pharmacol 66 2003 1635 1641
34. S.M. Bailey A review of the role of reactive oxygen and nitrogen species in alcohol-induced mitochondrial dysfunction Free Radic Res 37 2003 585 596
35. G.C. Brown Nitric oxide and mitochondrial respiration Biochim Biophys Acta 1411 1999 351 369
36. C. Fleury, B. Mignotte, and J.-L. Vayssiere Mitochondrial reactive oxygen species in cell death signaling Biochimie 84 2002 131 141
37. H. Hong, and G.Q. Liu Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin Life Sci 30 2004 2959 2973
38. A. Colell, C. Garcia-Ruiz, M. Miranda, E. Ardite, M. Mari, and A. Morales Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor Gastroenterology 115 1998 1541 1551
39. P.C. Constantini, B.C. Chernyak, V. Petronilli, and P. Bernardi Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites J Biochem Biol 271 1996 6746 6751