Effects of HRAS oncogene on cell cycle progression in a cervical cancer-derived cell line

Archives of Medical Research

Volumn 36, Issue 4, 2005, Pages 311-316

  Córdova Alarcón, Emilio ^a   Centeno, Federico ^a   Reyes Esparza, Jorge ^b   García Carrancá, Alejandro ^c,d   Garrido, Efraín ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DEL ESTADO DE MORELOS   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d SECRETARÍA DE SALUD   (Mexico)

Author keywords

Cervical carcinoma; Flow cytometry; HPV; RAS

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RAF PROTEIN;

ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL IMMORTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INACTIVATION; FLOW CYTOMETRY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE VECTOR; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; ONCOGENE; SIGNAL TRANSDUCTION; UTERINE CERVIX CANCER; WART VIRUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOTTING, WESTERN; BROMODEOXYURIDINE; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FEMALE; FLOW CYTOMETRY; G1 PHASE; GENES, RAS; HELA CELLS; HUMANS; MUTATION; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; PHOSPHORYLATION; S PHASE; TIME FACTORS; TRANSFECTION; UTERINE CERVICAL NEOPLASMS;

EID: 20444420843     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2005.04.001     Document Type: Article

References (32)

1. M.H. Einstein, and G.L. Goldberg Human papillomavirus and cervical neoplasia Cancer Invest 20 2002 1080 1085
2. M. Lizano, J. Berumen, M.C. Guido, L. Casas, and A. Garcia-Carranca Association between human papillomavirus type 18 variants and histopathology of cervical cancer J Natl Cancer Inst 89 1997 1227 1231
3. J.M. Walboomers, M.V. Jacobs, M.M. Manos, F.X. Bosch, J.A. Kummer, K.V. Shah, P.J. Snijders, J. Peto, C.J. Meijer, and N. Munoz Human papillomavirus is a necessary cause of invasive cervical cancer worldwide J Pathol 189 1999 12 19
4. H. Furumoto, and M. Irahara Human papillomavirus (HPV) and cervical cancer J Med Invest 49 2002 124 133
5. J.L. Bos ras oncogenes in human cancer Cancer Res 49 1989 4682 4689
6. S. Rodenhuis Ras and human tumors Semin Cancer Biol 3 1992 241 247
7. A. Stenzel, A. Semczuk, K. Rozynskal, J. Jakowicki, and J. Wojcierowski Low-risk and high-risk HPV-infection and K-ras gene point mutations in human cervical cancer: a study of 31 cases Pathol Res Pract 197 2001 597 603
8. L.V. Alonio, M.A. Picconi, D. Dalbert, J. Mural, O. Bartt, G. Bazan, M. Dominguez, and A.R. Teyssie Ha-ras oncogene mutation associated to progression of papillomavirus induced lesions of uterine cervix J Clin Virol 27 2003 263 269
9. V. Ayllon, and A. Rebollo Ras-induced cellular events Mol Membr Biol 17 2000 65 73
10. S.A. Moodie, B.M. Willumsen, M.J. Weber, and A. Wolfman Complexes of Ras GTP with Raf-1 and mitogen-activated protein kinase kinase Science 260 1993 1658 1661
11. P. Rodriguez-Viciana, P.H. Warne, R. Dhand, B. Vanhaesebroeck, I. Gout, M.J. Fry, M.D. Waterfield, and J. Downward Phosphatidylinositol-3-OH kinase as a direct target of Ras Nature 370 1994 527 532
12. J.T. Winston, S.R. Coats, Y.Z. Wang, and W.J. Pledger Regulation of the cell cycle machinery by oncogenic ras Oncogene 12 1996 127 134
13. M. Macaluso, G. Russo, C. Cinti, V. Bazan, N. Gebbia, and A. Russo Ras family genes: an interesting link between cell cycle and cancer J Cell Physiol 192 2002 125 130
14. D.S. Peeper, T.M. Upton, M.H. Ladha, E. Neuman, J. Zalvide, R. Bernards, J.A. DeCaprio, and M.E. Ewen Ras signaling linked to the cell-cycle machinery by the retinoblastoma protein Nature 386 1997 177 181
15. S. Mittnacht, H. Paterson, M.F. Olson, and C.J. Marshall Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein Curr Biol 7 1997 219 221
16. G. Leone, J. DeGregori, R. Sears, L. Jakoi, and J.R. Nevins Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F Nature 387 1997 422 426
17. E.I. Miranda, C. Santana, E. Rojas, S. Hernandez, P. Ostrosky-Wegman, and A. Garcia-Carranca Induced mitotic death of HeLa cells by abnormal expression of c-H-ras Mutat Res 349 1996 173 182
18. C. Santana, E. Ortega, and A. Garcia-Carranca Oncogenic H-ras induces cyclin B expression in a p53-independent manner Mutat Res 508 2002 49 58
19. J.R. Palisano The absence of confronting cisternae following thymidine-induced synchronization in HeLa cells Cell Biol Int 17 1993 653 664
20. P. Crespo, and J. Leon Ras proteins in the control of the cell cycle and cell differentiation Cell Mol Life Sci 57 2000 1613 1636
21. B.J. Warne-Cramer, G.T. Cottrel, J.U.M. Burt, and A.F. Lau Regulation of connexin-43 gap junctional intercellular communication by mitogen-activated protein kinase J Biol Chem 273 1998 9188 9196
22. H. Gille, and J. Downward Multiple ras effectors contribute to G1 cell cycle progression J Biol Chem 274 1999 22033 22040
23. A. Vidal, S.S. Millard, J.P. Miller, and A. Koff Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status J Biol Chem 277 2002 16433 16440
24. J.J. Yang, J.S. Kang, and R.S. Krauss Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth Mol Cell Biol 18 1998 2586 2595
25. A. Chaudhary, W.G. King, M.D. Mattaliano, J.A. Frost, B. Diaz, D.K. Morrison, M.H. Cobb, M.S. Marshall, and J.S. Brugge Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338 Curr Biol 10 2000 551 554
26. K.L. Guan, C. Figueroa, T.R. Brtva, T. Zhu, J. Taylor, T.D. Barber, and A.B. Vojtek Negative regulation of the serine/threonine kinase B-Raf by Akt J Biol Chem 275 2000 27354 27359
27. K. Moelling, K. Schad, M. Bosse, S. Zimmermann, and M. Schweneker Regulation of Raf-AKT cross-talk J Biol Chem 277 2002 31099 31106
28. S. Poser, S. Impey, K. Trinh, Z. Xia, and D.R. Storm SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation EMBO J 19 2000 4955 4966
29. E.C. Roberts, P.S. Shapiro, T.S. Nahreini, G. Pages, J. Pouyssegur, and N.G. Ahn Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis Mol Cell Biol 22 2002 7226 7241
30. M. Cheng, V. Sexl, C.J. Sherr, and M.F. Roussel Assembly of cyclin D-dependent kinase and titration of p27KIP1 regulated by mitogen-activated protein kinase kinase (MEK1) Proc Natl Acad Sci 95 1998 1091 1096
31. R.C. Muise-Helmericks, H.L. Grimes, A. Bellacosa, S.E. Malstrom, P.N. Tsichlis, and N. Rosen Cyclin D expression is controlled post-trancriptionally via a phosphatidylinositol 3-kinase/AKT-dependent pathway J Biol Chem 273 1998 29864 29872
32. N. Rivard, M.J. Boucher, C. Asselin, and G. L'Allemain MAP kinase cascade is required for p27 downregulation and S phase entry in fibroblast and epithelial cells Am J Physiol 277 1999 C652 C664