APeg3, a novel paternally expressed gene 3 antisense RNA transcript specifically expressed in vasopressinergic magnocellular neurons in the rat supraoptic nucleus

Molecular Brain Research

Volumn 137, Issue 1-2, 2005, Pages 143-151

  Glasgow, Eric ^a,b   Ryu, Seung Lim ^b,c   Yamashita, Mitsuo ^b,d   Zhang, Bing Jun ^b,e   Mutsuga, Noriko ^b   Gainer, Harold ^b  

^a NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Korea National Institute of Health   (South Korea)

^d OSAKA UNIVERSITY   (Japan)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

Antisense; Hypothalamus; Imprinted genes; Non coding RNA; Peg 3; Supraoptic nucleus; Vasopressin

Indexed keywords

COMPLEMENTARY RNA; GENE PRODUCT; VASOPRESSIN; ZINC FINGER PROTEIN;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ALLELE; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE LOCATION; GENE SEQUENCE; GENETIC TRANSCRIPTION; GIANT CELL; MALE; MATERNAL BEHAVIOR; MOLECULAR SIZE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PATERNALLY EXPRESSED GENE 3; PRIORITY JOURNAL; RAT; RNA ANALYSIS; SEQUENCE ANALYSIS; SUPRAOPTIC NUCLEUS;

3' UNTRANSLATED REGIONS; ANIMALS; CONSERVED SEQUENCE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENOMIC IMPRINTING; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MOLECULAR SEQUENCE DATA; NEURONS; PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; RNA, ANTISENSE; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPRAOPTIC NUCLEUS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VASOPRESSINS; WATER-ELECTROLYTE BALANCE;

ANIMALIA;

EID: 20444409467     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2005.02.030     Document Type: Article

References (50)

1. W.E. Armstrong Morphological and electrophysiological classification of hypothalamic supraoptic neurons Prog. Neurobiol. 47 1995 291 339
2. W.E. Armstrong, and J.E. Stern Electrophysiological distinctions between oxytocin and vasopressin neurons in the supraoptic nucleus Adv. Exp. Med. Biol. 449 1998 67 77
3. D.P. Barlow, R. Stoger, B.G. Herrmann, K. Saito, and N. Schweifer The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locu Nature 349 1991 84 87
4. M.S. Bartolomei, and S.M. Tilghman Genomic imprinting in mammals Annu. Rev. Genet. 31 1997 493 525
5. J.P. Burbach, H.S. van Schaick, F.M. de Bree, S. Lopes da Silva, and R.A. Adan Functional domains in the oxytocin gene for regulation of expression and biosynthesis of gene products Adv. Exp. Med. Biol. 395 1995 9 21
6. J.P. Burbach, S.M. Luckman, D. Murphy, and H. Gainer Gene regulation in the magnocellular hypothalamo-neurohypophysial system Physiol. Rev. 81 2001 1197 1267
7. S. Cawley, S. Bekiranov, H.H. Ng, P. Kapranov, E.A. Sekinger, D. Kampa, A. Piccolboni, V. Sementchenko, J. Cheng, A.J. Williams, R. Wheeler, B. Wong, J. Drenkow, M. Yamanaka, S. Patel, S. Brubaker, H. Tammana, G. Helt, K. Struhl, and T.R. Gingeras Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs Cell 116 2004 499 509
8. H. Gainer, and S. Wray Cellular and molecular biology of oxytocin and vasopressin E. Knobil J.D. Neill The physiology of reproduction 1994 Raven Press, Ltd. New York 1099 1129
9. G.I. Hatton Emerging concepts of structure-function dynamics in adult brain: the hypothalamo-neurohypophysial system Prog. Neurobiol. 34 1990 437 504
10. G.I. Hatton Function-related plasticity in hypothalamus Annu. Rev. Neurosci. 20 1997 375 397
11. E. Hollander, S. Novotny, M. Hanratty, R. Yaffe, C.M. DeCaria, B.R. Aronowritz, and S. Mosovich Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger's disorders Neuropsychopharmacology 28 2003 193 198
12. M. Inouye Antisense RNA: its functions and applications in gene regulation-A review Gene 72 1988 25 34
13. T.R. Insel, J.T. Winslow, J.R. Williams, N. Hastings, L.E. Shapiro, and C.S. Carter The role of neurohypophyseal peptides in the central mediation of complex social processes-Evidence from comparative studies Regul. Pept. 45 1993 127 131
14. T.R. Insel, D.J. O'Brien, and J.F. Leckman Oxytocin, vasopressin, and autism: is there a connection? Biol. Psychiatry 45 1999 145 157
15. R.M. John, and M.A. Surani Genomic imprinting, mammalian evolution, and the mystery of egg-laying mammals Cell 101 2000 585 588
16. T. Kaneko-Ishino, Y. Kuroiwa, N. Miyoshi, T. Kohda, R. Suzuki, M. Yokoyama, S. Viville, S.C. Barton, F. Ishino, and M.A. Surani Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization Nat. Genet. 11 1995 52 59
17. E.B. Keverne Genomic imprinting in the brain Curr. Opin. Neurobiol. 7 1997 463 468
18. E.B. Keverne Genomic imprinting, maternal care, and brain evolution Horm. Behav. 40 2001 146 155
19. J. Kim, L. Ashworth, E. Branscomb, and L. Stubbs The human homolog of a mouse-imprinted gene, Peg3, maps to a zinc finger gene-rich region of human chromosome 19q13.4 Genome Res. 7 1997 532 540
20. J. Kim, X. Lu, and L. Stubbs Zim1, a maternally expressed mouse Kruppel-type zinc-finger gene located in proximal chromosome 7 Hum. Mol. Genet. 8 1999 847 854
21. J. Kim, A. Bergmann, and L. Stubbs Exon sharing of a novel human zinc-finger gene, ZIM2, and paternally expressed gene 3 (PEG3) Genomics 64 2000 114 118
22. J. Kim, V.N. Noskov, X. Lu, A. Bergmann, X. Ren, T. Warth, P. Richardson, N. Kouprina, and L. Stubbs Discovery of a novel, paternally expressed ubiquitin-specific processing protease gene through comparative analysis of an imprinted region of mouse chromosome 7 and human chromosome 19q13.4 Genome Res. 10 2000 1138 1147
23. J. Kim, A. Kollhoff, A. Bergmann, and L. Stubbs Methylation-sensitive binding of transcription factor YY1 to an insulator sequence within the paternally expressed imprinted gene, Peg3 Hum. Mol. Genet. 12 2003 233 245
24. H. Kiyosawa, I. Yamanaka, N. Osato, S. Kondo, and Y. Hayashizaki Antisense transcripts with FANTOM2 clone set and their implication for gene regulation Genome Res. 13 2003 1324 1334
25. Y. Kuroiwa, T. Kaneko-Ishino, F. Kagitani, T. Kohda, L.L. Li, M. Tada, R. Suzuki, M. Yokoyama, T. Shiroishi, S. Wakana, S.C. Barton, F. Ishino, and M.A. Surani Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein Nat. Genet. 12 1996 186 190
26. G. Lavorgna, D. Dahary, B. Lehner, R. Sorek, C.M. Sanderson, and G. Casari In search of antisense Trends Biochem. Sci. 29 2004 88 94
27. C. Le Moine, and W.S. Young III RHS2, a POU domain-containing gene, and its expression in developing and adult rat Proc. Natl. Acad. Sci. U. S. A. 89 1992 3285 3289
28. J.F. Leckman, W.K. Goodman, W.G. North, P.B. Chappell, L.H. Price, D.L. Pauls, G.M. Anderson, M.A. Riddle, M. McSwiggan-Hardin, C.J. McDougle, and E. Al Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls Arch. Gen. Psychiatry 51 1994 782 792
29. L. Li, E.B. Keverne, S.A. Aparicio, F. Ishino, S.C. Barton, and M.A. Surani Regulation of maternal behavior and offspring growth by paternally expressed Peg3 Science 284 1999 330 333
30. B. Meister Gene expression and chemical diversity in hypothalamic neurosecretory neurons Mol. Neurobiol. 7 1993 87 110
31. C. Modahl, L. Green, D. Fein, M. Morris, L. Waterhouse, C. Feinstein, and H. Levin Plasma oxytocin levels in autistic children Biol. Psychiatry 43 1998 270 277
32. T. Moore, M. Constancia, M. Zubair, B. Bailleul, R. Feil, H. Sasaki, and W. Reik Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2 Proc. Natl. Acad. Sci. U. S. A. 94 1997 12509 12514
33. I.M. Morison, C.J. Paton, and S.D. Cleverley The imprinted gene and parent-of-origin effect database Nucleic Acids Res. 29 2001 275 276
34. N. Mutsuga, T. Shahar, J.G. Verbalis, M.J. Brownstein, C.C. Xiang, R.F. Bonner, and H. Gainer Selective gene expression in magnocellular neurons in rat supraoptic nucleus J. Neurosci. 24 2004 7174 7185
35. F. Relaix, X. Weng, G. Marazzi, E. Yang, N. Copeland, N. Jenkins, S. Spence, and D. Sassoon Pw1, a novel zinc finger gene implicated in the myogenic and neuronal lineages Dev. Biol. 177 1996 383 396
36. J. Sambrook, E. Fritsch, and T. Maniatis Molecular cloning: a laboratory manual 2nd edn. 1989 Cold Spring Harbor Laboratory Press Cold Spring Harbor, New York
37. R.W. Simons Naturally occurring antisense RNA control-A brief review Gene 72 1988 35 44
38. R. Stoger, P. Kubicka, C.G. Liu, T. Kafri, A. Razin, H. Cedar, and D.P. Barlow Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal Cell 73 1993 61 71
39. D.F. Swaab, J.S. Purba, and M.A. Hofman Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: a study of five cases J. Clin. Endocrinol. Metab. 80 1995 573 579
40. I.Y. Szeto, L.L. Li, and M.A. Surani Ocat, a paternally expressed gene closely linked and transcribed in the opposite direction to Peg3 Genomics 67 2000 221 227
41. S.M. Tilghman The sins of the fathers and mothers: genomic imprinting in mammalian development Cell 96 1999 185 193
42. C. Tufarelli, J.A. Stanley, D. Garrick, J.A. Sharpe, H. Ayyub, W.G. Wood, and D.R. Higgs Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease Nat. Genet. 34 2003 157 165
43. R.I. Verona, M.R. Mann, and M.S. Bartolomei Genomic imprinting: intricacies of epigenetic regulation in clusters Annu. Rev. Cell Dev. Biol. 19 2003 237 259
44. S.J. Waller, A. Ratty, J.P. Burbach, and D. Murphy Transgenic and transcriptional studies on neurosecretory cell gene expression Cell Mol. Neurobiol. 18 1998 149 171
45. A. Wutz, O.W. Smrzka, N. Schweifer, K. Schellander, E.F. Wagner, and D.P. Barlow Imprinted expression of the Igf2r gene depends on an intronic CpG island Nature 389 1997 745 749
46. M. Yamashita, E. Glasgow, B.J. Zhang, K. Kusano, and H. Gainer Identification of cell-specific messenger ribonucleic acids in oxytocinergic and vasopressinergic magnocellular neurons in rat supraoptic nucleus by single-cell differential hybridization Endocrinology 143 2002 4464 4476
47. R. Yelin, D. Dahary, R. Sorek, E.Y. Levanon, O. Goldstein, A. Shoshan, A. Diber, S. Biton, Y. Tamir, R. Khosravi, S. Nemzer, E. Pinner, S. Walach, J. Bernstein, K. Savitsky, and G. Rotman Widespread occurrence of antisense transcription in the human genome Nat. Biotechnol. 21 2003 379 386
48. W.S.I. Young Expression of the oxytocin and vasopressin genes J. Neuroendocrinol. 4 1992 529 540
49. L.J. Young Oxytocin and vasopressin receptors and species-typical social behaviors Horm. Behav. 36 1999 212 221
50. W.S. Young, and H. Gainer Transgenesis and the study of expression, cellular targeting and function of oxytocin, vasopressin and their receptors Neuroendocrinology 78 2003 185 203