Interleukin-4 protects matrix synthesis in chondrocytes under excessive mechanical stress in vitro

Modern Rheumatology

Volumn 14, Issue 4, 2004, Pages 296-300

  Shimizu, Akira ^a   Watanabe, Shohei ^a   Iimoto, Seiji ^a   Yamamoto, Haruyasu ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chondrocytes; Fibronectin(FN); Integrin l(INTb1); Interleukin 4(IL 4); Mechanical stress

Indexed keywords

AGGRECAN; BETA1 INTEGRIN; CARBON DIOXIDE; COLLAGEN TYPE 2; FIBRONECTIN; INTERLEUKIN 4; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ARTICULAR CARTILAGE; BONE MATRIX; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL PROTECTION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; IN VITRO STUDY; MECHANICAL STRESS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RAT STRAIN; REAL TIME POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE;

EID: 20444404271     PISSN: 14397595     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10165-004-0312-7     Document Type: Article

References (25)

1. Palmoski MJ, Brandt KD. Effects of static and cyclic compressive loading on articular cartilage plugs in vitro. Arthritis Rheum 1984;27:675-81.
2. Gray ML, Pizzanelli AM, Grodzinsky AJ, Lee RC. Mechanical and physiochemical determinants of the chondrocyte biosynthetic response. J Orthop Res 1988;6:777-92.
3. Grodzinsky AJ, Levenston ME, Jin M, Lee RC. Cartilage tissue remodeling in response to mechanical forces. Annu Rev Biomed Eng 2000;2:691-713.
4. Guilak F, Ratcliffe A, Lane N, Rosenwasser MP, Mow VC. Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis. J Orthop Res 1994;12:474-84.
5. Loening AM, James IE, Levenston ME, Badger AM, Frank EH, Kurz B, et al. Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis. Arch Biochem Biophys 2000;381:205-12.
6. Bachrach NM, Valhmu WB, Stazzone E, Ratcliffe A, Lai WM, Mow VC. Changes in proteoglycan synthesis of chondrocytes in articular cartilage are associated with the time-dependent changes in their mechanical environment. J Biomech 1995;28:1561-9.
7. Fukuda K, Asada S, Kumano F, Hara F, Matsukawa M, Otani K, et al. Cyclic tensile stretch on bovine articular chondrocytes inhibits protein kinase C activity. J Lab Clin Med 1997;130:209-15.
8. Honda K, Ohno S, Tanimoto K, Ijuin C, Tanaka N, Doi T, et al. The effects of high-magnitude cyclic tensile load on cartilage matrix metabolism in cultured chondrocytes. Eur J Cell Biol 2000;79:601-9.
9. Mow VC, Ratcliffe A, Poole AR. Cartilage and diarthrodial joints as paradigms for hierarchical materials and structures. Biomaterials 1992;13:67-97.
10. Steinmeyer J, Ackermann B, Raiss RX. Intermittent cyclic loading of cartilage explants modulates fibronectin metabolism. Osteoarthritis Cartilage 1997;5:331-41.
11. Toyoda T, Saito S, Inokuchi S. The effects of tensile load on the metabolism of cultured chondrocytes. Clin Orthop 1999;359:221-8.
12. Wong M, Siegrist M, Cao X. Cyclic compression of articular cartilage explants is associated with progressive consolidation and altered expression pattern of extracellular matrix proteins. Matrix Biol 1999;18:391-9.
13. Yeh LA, Augustine AJ, Lee P, Riviere LR, Sheldon A. Interleukin-4, an inhibitor of cartilage breakdown in bovine articular cartilage explants. J Rheumatol 1995;22:1740-6.
14. Millward-Sadler SJ, Wright MO, Lee H, Nishida K, Caldwell H, Nuki G, et al. Integrin-regulated secretion of interleukin 4: A novel pathway of mechanotransduction in human articular chondrocytes. J Cell Biol 1999;145:183-9.
15. Bruckner P, Horler I, Mendler M, Houze Y, Winterhalter KH, Eich-Bender SG, et al. Induction and prevention of chondrocyte hypertrophy in culture. J Cell Biol 1989;109:2537-45.
16. Banes AJ, Link GW Jr, Gilbert JW, Tran Son Tay R, Monbureau O. Culturing cells in a mechanically active environment. Am Biotechnol Lab 1990;8:2-22.
17. Wittwer CT, Ririe KM, Andrew RV, David DA, Gundry RA, Balis UJ. The LightCycler: A microvolume multisample fluorimeter with rapid temperature control. Biotechniques 1997;22:176-81.
18. Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J Cell Sci 1995;108:1497-508.
19. Fujisawa T, Hattori T, Takahashi K, Kuboki T, Yamashita A, Takigawa M. Cyclic mechanical stress induces extracellular matrix degradation in cultured chondrocytes via gene expression of matrix metalloproteinases and interleukin-1. J Biochem 1999;125:966-75.
20. Smith RL, Lin J, Trindade MC, Shida J, Kajiyama G, Vu T, et al. Time-dependent effects of intermittent hydrostatic pressure on articular chondrocyte type II collagen and aggrecan mRNA expression. J Rehabil Res Dev 2000;37:153-61.
21. Liao NS, St John J, McCarthy JB, Furcht LT, Cheung HT. Adhesion of lymphoid cells to the carboxyl-terminal heparin-binding domains of fibronectin. Exp Cell Res 1989;181:348-61.
22. McCarthy JB, Skubitz AP, Qi Z, Yi XY, Mickelson DJ, Klein DJ, et al. RGD-independent cell adhesion to the carboxy-terminal heparin-binding fragment of fibronectin involves heparin-dependent and -independent activities. J Cell Biol 1990;110:777-87.
23. Burton-Wurster N, Butler M, Harter S, Colombo C, Quintavalla J, Swartzendurber D, et al. Presence of fibronectin in articular cartilage in two animal models of osteoarthritis. J Rheumatol 1986;13:175-8.
24. Chevalier X, Groult N, Labat-Robert J. Biosynthesis and distribution of fibronectin in normal and osteoarthritic human cartilage. Clin Physiol Biochem 1992;9:1-6.
25. Hynes RO. Integrins: Versatility, modulation, and signaling in cell adhesion [review]. Cell 1992;69:11-25.