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Volumn 30, Issue 2, 2005, Pages 111-126

Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants

Author keywords

Glutathione S transferase; Glyceraldehyde 3 phosphate dehydrogenase; Phosphatidylethanolamine binding protein; Proteomics; Testicular toxicity; Testis specific heat shock protein 70 2

Indexed keywords

2 METHOXYETHANOL; ACETONYLACETONE; BIOLOGICAL MARKER; CYCLOPHOSPHAMIDE; GLUTATHIONE TRANSFERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEAT SHOCK PROTEIN 70; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; SALAZOSULFAPYRIDINE; UNCLASSIFIED DRUG;

EID: 20444402314     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.30.111     Document Type: Article
Times cited : (24)

References (46)
  • 1
    • 0036525708 scopus 로고    scopus 로고
    • Toxicoproteomics - A new preclinical tool
    • Bandara, L.R. and Kennedy, S. (2002): Toxicoproteomics - a new preclinical tool. Drug Discovery Today, 7, 411-418.
    • (2002) Drug Discovery Today , vol.7 , pp. 411-418
    • Bandara, L.R.1    Kennedy, S.2
  • 2
    • 50549187947 scopus 로고
    • Sulphasalazine and salicylazosulphamidine in ulcerative colitis
    • Baron, J.M., Connell, A.M., Lennard-Jones, J.E. and Jones, RA. (1962): Sulphasalazine and salicylazosulphamidine in ulcerative colitis. Lancet, 1, 1094.
    • (1962) Lancet , vol.1 , pp. 1094
    • Baron, J.M.1    Connell, A.M.2    Lennard-Jones, J.E.3    Jones, R.A.4
  • 3
    • 0030005783 scopus 로고    scopus 로고
    • Fate of germ cells in 2,5-hexanedione-induced testicular injury. I. Apoptosis is the mechanism of germ cell death
    • Blanchard, K.T., Allard, E.K. and Boekelheide, K. (1996): Fate of germ cells in 2,5-hexanedione-induced testicular injury. I. Apoptosis is the mechanism of germ cell death. Toxicol. Appl. Pharmacol., 137, 141-148.
    • (1996) Toxicol. Appl. Pharmacol. , vol.137 , pp. 141-148
    • Blanchard, K.T.1    Allard, E.K.2    Boekelheide, K.3
  • 4
    • 0023240549 scopus 로고
    • 2,5-Hexanedione alters microtubule assembly. I. Testicular atrophy, not nervous system toxicity, correlates with enhanced tubulin polymerization
    • Boekelheide, K. (1987a): 2,5-Hexanedione alters microtubule assembly. I. Testicular atrophy, not nervous system toxicity, correlates with enhanced tubulin polymerization. Toxicol. Appl. Pharmacol., 88, 370-382.
    • (1987) Toxicol. Appl. Pharmacol. , vol.88 , pp. 370-382
    • Boekelheide, K.1
  • 5
    • 0023279529 scopus 로고
    • 2,5-Hexanedione alters microtubule assembly. II. Enhanced polymerization of crosslinked tubulin
    • Boekelheide, K. (1987b): 2,5-Hexanedione alters microtubule assembly. II. Enhanced polymerization of crosslinked tubulin. Toxicol. Appl. Pharmacol., 88, 383-396.
    • (1987) Toxicol. Appl. Pharmacol. , vol.88 , pp. 383-396
    • Boekelheide, K.1
  • 6
    • 0023860977 scopus 로고
    • Rat testis during 2,5-hexanedione intoxication and recovery. II. Dynamics of pyrrole reactivity, tubulin content, and microtubule assembly
    • Boekelheide, K. (1988): Rat testis during 2,5-hexanedione intoxication and recovery. II. Dynamics of pyrrole reactivity, tubulin content, and microtubule assembly. Toxicol. Appl. Pharmacol., 92, 28-33.
    • (1988) Toxicol. Appl. Pharmacol. , vol.92 , pp. 28-33
    • Boekelheide, K.1
  • 8
    • 0020534092 scopus 로고
    • The morphologenesis of testicular degeneration induced in rats by orally administered 2,5-hexanedione
    • Chapin, R.E., Morgan, K.T. and Bus, J.S. (1983): The morphologenesis of testicular degeneration induced in rats by orally administered 2,5-hexanedione. Exp. Mol. Pathol., 38, 149-169.
    • (1983) Exp. Mol. Pathol. , vol.38 , pp. 149-169
    • Chapin, R.E.1    Morgan, K.T.2    Bus, J.S.3
  • 9
    • 0021491051 scopus 로고
    • The effects of ethylene glycol monomethyl ether on testicular histology in F344 rats
    • Chapin, R.E., Dutton, S.L., Ross, M.D., Sumrell, B.M. and Lamb, J.C. IV (1984): The effects of ethylene glycol monomethyl ether on testicular histology in F344 rats. J. Androl., 5, 369-380.
    • (1984) J. Androl. , vol.5 , pp. 369-380
    • Chapin, R.E.1    Dutton, S.L.2    Ross, M.D.3    Sumrell, B.M.4    Lamb IV, J.C.5
  • 10
    • 0030988088 scopus 로고    scopus 로고
    • Evaluation of testicular toxicity in safety evaluation studies: The appropriate use of spermatogenic staging
    • Creasy, D.M. (1997): Evaluation of testicular toxicity in safety evaluation studies: The appropriate use of spermatogenic staging. Toxicol. Pathol., 25, 119-131.
    • (1997) Toxicol. Pathol. , vol.25 , pp. 119-131
    • Creasy, D.M.1
  • 11
    • 0035199033 scopus 로고    scopus 로고
    • Decreased expression of the heat shock protein hsp70-2 is associated with the pathogenesis of male infertility
    • Feng, H.L., Sandlow, J.I. and Sparke, A.E. (2001): Decreased expression of the heat shock protein hsp70-2 is associated with the pathogenesis of male infertility. Fertil. Steril., 76, 1136-1139.
    • (2001) Fertil. Steril. , vol.76 , pp. 1136-1139
    • Feng, H.L.1    Sandlow, J.I.2    Sparke, A.E.3
  • 12
    • 2642629060 scopus 로고
    • The effects of pharmaceuticals, environmental, and occupational agents on sperm motility
    • (Gagnon, C., ed.), CRC press, Boca Raton, FL
    • Fisher-Fischbein, J. (1990): The effects of pharmaceuticals, environmental, and occupational agents on sperm motility. In (Gagnon, C., ed.), Controls of sperm motility: Biological and clinical aspect., pp. 349-373, CRC press, Boca Raton, FL.
    • (1990) Controls of Sperm Motility: Biological and Clinical Aspect , pp. 349-373
    • Fisher-Fischbein, J.1
  • 15
    • 0031917789 scopus 로고    scopus 로고
    • Expression of phosphatidylethanolamine-binding protein in the male reproductive tract: Immunolocalisation and expression in prepubertal and adult rat testes and epididymis
    • Frayne, J., McMillen, A., Love, S. and Hall, L. (1998): Expression of phosphatidylethanolamine-binding protein in the male reproductive tract: Immunolocalisation and expression in prepubertal and adult rat testes and epididymis. Mol. Reprod. Dev., 49, 454-460.
    • (1998) Mol. Reprod. Dev. , vol.49 , pp. 454-460
    • Frayne, J.1    McMillen, A.2    Love, S.3    Hall, L.4
  • 16
    • 0036234309 scopus 로고    scopus 로고
    • Analysis of gene and protein expression for drug mode of toxicity
    • Furness, L.M. (2002): Analysis of gene and protein expression for drug mode of toxicity. Curr. Opin. Drug Discov. Dev., 5, 98-103.
    • (2002) Curr. Opin. Drug Discov. Dev. , vol.5 , pp. 98-103
    • Furness, L.M.1
  • 17
    • 0003130095 scopus 로고
    • Statistics for lexicologists
    • (Hyes, A.M., ed.), Raven Press, New York
    • Gad, S.C. and Weil, C.S. (1994): Statistics for lexicologists. In Principles and Methods of Toxicology (Hyes, A.M., ed.), pp. 221-274, Raven Press, New York.
    • (1994) Principles and Methods of Toxicology , pp. 221-274
    • Gad, S.C.1    Weil, C.S.2
  • 18
    • 0027333423 scopus 로고
    • Role of the major heat shock proteins as molecular chaperones
    • Georgopoulos, C. and Welch, W.J. (1993): Role of the major heat shock proteins as molecular chaperones. Ann. Rev. Cell Biol., 9, 601-634.
    • (1993) Ann. Rev. Cell Biol. , vol.9 , pp. 601-634
    • Georgopoulos, C.1    Welch, W.J.2
  • 19
    • 0029566336 scopus 로고
    • The role of molecular chaperones in protein folding
    • Hendrck, J.P. and Hartl, F.U. (1995): The role of molecular chaperones in protein folding. FASEB J., 9, 1559-1569.
    • (1995) FASEB J. , vol.9 , pp. 1559-1569
    • Hendrck, J.P.1    Hartl, F.U.2
  • 21
    • 0034059992 scopus 로고    scopus 로고
    • Rat epididymal sperm motion changes induced by ethylene glycol monomethyl ether, sulfasalazine, and 2,5-hexandione
    • Horimoto, M., Isobe, Y., Isogai, Y. and Tachibana, M. (2000): Rat epididymal sperm motion changes induced by ethylene glycol monomethyl ether, sulfasalazine, and 2,5-hexandione. Reprod. Toxicol., 14, 55-63.
    • (2000) Reprod. Toxicol. , vol.14 , pp. 55-63
    • Horimoto, M.1    Isobe, Y.2    Isogai, Y.3    Tachibana, M.4
  • 22
    • 0028838971 scopus 로고
    • Protein kinase and phosphatase: The yin and yang of protein phosphorylation and signaling
    • Hunter, T. (1994): Protein kinase and phosphatase: The yin and yang of protein phosphorylation and signaling. Cell, 80, 225-236.
    • (1994) Cell , vol.80 , pp. 225-236
    • Hunter, T.1
  • 23
    • 0026636883 scopus 로고
    • The regulation of transcription by phosphorylation
    • Hunter, T. and Karin, M. (1992): The regulation of transcription by phosphorylation. Cell, 70, 375-387.
    • (1992) Cell , vol.70 , pp. 375-387
    • Hunter, T.1    Karin, M.2
  • 24
    • 0028333768 scopus 로고
    • Sequential protein kinase reactions controlling cell growth and differentiation
    • Johnson, G.L. and Vaillancourt, R.R. (1994): Sequential protein kinase reactions controlling cell growth and differentiation. Curr. Opin. Cell Biol., 6, 230-238.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 230-238
    • Johnson, G.L.1    Vaillancourt, R.R.2
  • 26
    • 0023145719 scopus 로고
    • Identification and characterization of the 2D6 and Mr 23000 antigens on the plasma membrane of rat spermatozoa
    • Jones, R. and Brown, C.R. (1987): Identification and characterization of the 2D6 and Mr 23000 antigens on the plasma membrane of rat spermatozoa. Biochem. J., 241, 353-360.
    • (1987) Biochem. J. , vol.241 , pp. 353-360
    • Jones, R.1    Brown, C.R.2
  • 27
    • 0026043708 scopus 로고
    • A 23 kDa protein from rat sperm plasma membranes shows sequence similarity and phospholipid binding properties to a bovine cytosolic protein
    • Jones, R. and Halls, L. (1991): A 23 kDa protein from rat sperm plasma membranes shows sequence similarity and phospholipid binding properties to a bovine cytosolic protein. Biochim. Biophys. Acta, 1080, 78-82.
    • (1991) Biochim. Biophys. Acta , vol.1080 , pp. 78-82
    • Jones, R.1    Halls, L.2
  • 28
    • 0029328342 scopus 로고
    • Transcriptional control by protein phosphorylation: Signal transmission from the cell surface to the nucleus
    • Karin, M. and Hunter, T. (1995): Transcriptional control by protein phosphorylation: Signal transmission from the cell surface to the nucleus. Curr. Biol., 5, 747-757.
    • (1995) Curr. Biol. , vol.5 , pp. 747-757
    • Karin, M.1    Hunter, T.2
  • 29
    • 0028979833 scopus 로고
    • Spermatocyte toxicity of 2-methoxyethanol (ME) in rats and guinea pigs: Evidence for the induction of apoptosis
    • Ku, W.W., Wine, R.N., Chae, B.Y., Ghanayem, B.I. and Chapin, R.E. (1995): Spermatocyte toxicity of 2-methoxyethanol (ME) in rats and guinea pigs: Evidence for the induction of apoptosis. Toxicol. Appl. Pharmacol., 134, 100-110.
    • (1995) Toxicol. Appl. Pharmacol. , vol.134 , pp. 100-110
    • Ku, W.W.1    Wine, R.N.2    Chae, B.Y.3    Ghanayem, B.I.4    Chapin, R.E.5
  • 30
    • 18544405747 scopus 로고
    • Testicular and germ cell toxicity: In vitro approaches
    • Lamb, J.C. IV and Chapin, R.E. (1993): Testicular and germ cell toxicity: In vitro approaches. Reprod. Toxicol., 7, 17-22.
    • (1993) Reprod. Toxicol. , vol.7 , pp. 17-22
    • Lamb IV, J.C.1    Chapin, R.E.2
  • 31
    • 0033636283 scopus 로고    scopus 로고
    • Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers
    • Liang, E., Proudfoot, J. and Yazdianian, M. (2000): Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers. Pharm. Res., 17, 1168-1707.
    • (2000) Pharm. Res. , vol.17 , pp. 1168-1707
    • Liang, E.1    Proudfoot, J.2    Yazdianian, M.3
  • 32
    • 0029097126 scopus 로고
    • Morphological evaluations of cyclophosphamide testicular toxicity in rats using quantitative morphometry of spermatogenic cycle stages
    • Matsui, H., Mitsumori, K., Yasuhara, K., Onodera, H., Shimo, T. and Takahashi, M. (1995): Morphological evaluations of cyclophosphamide testicular toxicity in rats using quantitative morphometry of spermatogenic cycle stages. Toxicol. Sci., 20, 407-414.
    • (1995) Toxicol. Sci. , vol.20 , pp. 407-414
    • Matsui, H.1    Mitsumori, K.2    Yasuhara, K.3    Onodera, H.4    Shimo, T.5    Takahashi, M.6
  • 33
    • 0021615259 scopus 로고
    • Metabolism of pachytene primary spermatocytes from rat testes: Pyruvate maintenance of adenosine triphosphate level
    • Nakamura, M., Okinaga, S. and Arai, K. (1984): Metabolism of pachytene primary spermatocytes from rat testes: Pyruvate maintenance of adenosine triphosphate level. Biol. Reprod., 30, 1187-1197.
    • (1984) Biol. Reprod. , vol.30 , pp. 1187-1197
    • Nakamura, M.1    Okinaga, S.2    Arai, K.3
  • 34
    • 0028944739 scopus 로고
    • 2 subunits of Glutathione 5-Transferase in the testis and epididymis of adult rats
    • 2 subunits of Glutathione 5-Transferase in the testis and epididymis of adult rats. Microsc. Res. Tech., 30, 1-23.
    • (1995) Microsc. Res. Tech. , vol.30 , pp. 1-23
    • Papp, S.1    Robaire, B.2    Hermo, L.3
  • 35
    • 0028352920 scopus 로고
    • Sequence analysis of a mammalian phospholipid-binding protein from testis and epididymis and its distribution between spermatozoa and extracellular secretions
    • Perry, A.C.F., Hall, L., Bell, A.E. and Jones, R. (1994): Sequence analysis of a mammalian phospholipid-binding protein from testis and epididymis and its distribution between spermatozoa and extracellular secretions. Biochem. J., 301, 235-242.
    • (1994) Biochem. J. , vol.301 , pp. 235-242
    • Perry, A.C.F.1    Hall, L.2    Bell, A.E.3    Jones, R.4
  • 36
    • 0028848621 scopus 로고
    • Damage to rat spermatozoal DNA after chronic cyclophosphamide exposure
    • Qiu, J., Hales, B.F. and Robaire, B. (1995): Damage to rat spermatozoal DNA after chronic cyclophosphamide exposure. Biol. Replod., 53, 1465-1473.
    • (1995) Biol. Replod. , vol.53 , pp. 1465-1473
    • Qiu, J.1    Hales, B.F.2    Robaire, B.3
  • 37
    • 0033652866 scopus 로고    scopus 로고
    • Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats - Overview of the studies
    • Sakai, T., Takahashi, M., Mitsumori, K., Yasuhara, K., Kawashima, K., Mayahara, H. and Ohno, Y. (2000): Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats - overview of the studies -. J. Toxicol. Sci., 25, 1-21.
    • (2000) J. Toxicol. Sci. , vol.25 , pp. 1-21
    • Sakai, T.1    Takahashi, M.2    Mitsumori, K.3    Yasuhara, K.4    Kawashima, K.5    Mayahara, H.6    Ohno, Y.7
  • 39
    • 0030046845 scopus 로고    scopus 로고
    • Characterization and localization of the rat, mouse and human testicular phosphatidylethanolamine binding protein
    • Seddiqi, N., Segretain, B.D., Buequoy, S., Pineau, C., Jegou, B., Jolles, P. and Schoentgen, F. (1996): Characterization and localization of the rat, mouse and human testicular phosphatidylethanolamine binding protein. Experimentia, 52, 101-110.
    • (1996) Experimentia , vol.52 , pp. 101-110
    • Seddiqi, N.1    Segretain, B.D.2    Buequoy, S.3    Pineau, C.4    Jegou, B.5    Jolles, P.6    Schoentgen, F.7
  • 40
    • 0036077621 scopus 로고    scopus 로고
    • The crystal structure of PEBP-2, a homologue of the PEBP/RKIP family
    • Simister, P.C., Banfield, M.J. and Brady, R.L. (2002): The crystal structure of PEBP-2, a homologue of the PEBP/RKIP family. Acta Cryst., D58, 1077-1080.
    • (2002) Acta Cryst. , vol.D58 , pp. 1077-1080
    • Simister, P.C.1    Banfield, M.J.2    Brady, R.L.3
  • 41
    • 84982333870 scopus 로고
    • Salazopyrine, a new sulfanilamide preparation
    • Svartz, N. (1942): Salazopyrine, a new sulfanilamide preparation. Acta. Med. Scand., 110, 577-598.
    • (1942) Acta. Med. Scand. , vol.110 , pp. 577-598
    • Svartz, N.1
  • 42
    • 0000355949 scopus 로고
    • Mechanism of testicular toxicity
    • Takahashi, M. and Matsui, H. (1993): Mechanism of testicular toxicity. J. Toxicol. Pathol., 6, 161-174.
    • (1993) J. Toxicol. Pathol. , vol.6 , pp. 161-174
    • Takahashi, M.1    Matsui, H.2
  • 43
    • 0036043671 scopus 로고    scopus 로고
    • Toxicogenomics and drug discovery: Will new technologies help us produce better drugs?
    • Ulrich, R. and Friend, S.H. (2002): Toxicogenomics and drug discovery: Will new technologies help us produce better drugs? Nature Reviews. Drug Discovery, 1, 153-161.
    • (2002) Nature Reviews. Drug Discovery , vol.1 , pp. 153-161
    • Ulrich, R.1    Friend, S.H.2
  • 45
    • 0033936223 scopus 로고    scopus 로고
    • Differential gene expression detected by suppression subtractive hybridization in the ethylene glycol monomethyl ether-induced testicular lesion
    • Wang, W. and Chapin, R.E. (2000): Differential gene expression detected by suppression subtractive hybridization in the ethylene glycol monomethyl ether-induced testicular lesion. Toxicol. Sci., 56, 165-174.
    • (2000) Toxicol. Sci. , vol.56 , pp. 165-174
    • Wang, W.1    Chapin, R.E.2
  • 46
    • 0036746524 scopus 로고    scopus 로고
    • Mapping of phosphorylated proteins on two-dimensional polyacrylamide gels using protein phosphatase
    • Yamagata, A., Kristensen, D.B., Takeda, Y., Miyamoto, Y., Okada, K., Inamatsu, M. and Yoshizato, K. (2002): Mapping of phosphorylated proteins on two-dimensional polyacrylamide gels using protein phosphatase. Proteomics, 2, 1267-1276.
    • (2002) Proteomics , vol.2 , pp. 1267-1276
    • Yamagata, A.1    Kristensen, D.B.2    Takeda, Y.3    Miyamoto, Y.4    Okada, K.5    Inamatsu, M.6    Yoshizato, K.7


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