Corymine potentiates NMDA-induced currents in Xenopus oocytes expressing NR1a/NR2B glutamate receptors

Journal of Pharmacological Sciences

Volumn 98, Issue 1, 2005, Pages 58-65

  Leewanich, Pathama ^a,b   Tohda, Michihisa ^b   Takayama, Hiromitsu ^c   Sophasan, Samaisukh ^d   Watanabe, Hiroshi ^b   Matsumoto, Kinzo ^b  

^a SRINAKHARINWIROT UNIVERSITY   (Thailand)

^b UNIVERSITY OF TOYAMA   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d Mahidol University ^*  (Thailand)

Author keywords

Corymine; NR1a NR2B NMDA receptor; Potentiating effect; Xenopus oocyte

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CHLORIDE CHANNEL BLOCKING AGENT; COMPLEMENTARY RNA; CORYMINE; DIZOCILPINE; GLUTAMATE RECEPTOR; GLYCINE; INDOLE ALKALOID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SPERMINE; STRYCHNINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CORRELATION ANALYSIS; EVALUATION; HUNTER ZEYLANICA; NONHUMAN; OOCYTE; PLANT; PLANT LEAF; PROTEIN EXPRESSION; SEIZURE; VOLTAGE CLAMP; XENOPUS LAEVIS;

EID: 20444399567     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.FP0050023     Document Type: Article

References (44)

1. Leewanich P, Tohda M, Matsumoto K, Subhadhirasakul S, Takayama H, Aimi N, et al. Behavioral studies on alkaloids extracted from the laeves of Hunteria zeylanica. Biol Pharm Bull. 1996;19:394-399.
2. Leewanich P, Tohda M, Matsumoto K, Subhadhirasakul S, Takayama H, Aimi N, et al. Inhibitory effects of corymine, an alkaloidal component from the laeves of Hunteria zeylanica, on glycine receptor expressed in Xenopus oocytes. Eur J Pharmacol. 1997;332:321-326.
3. Leewanich P, Tohda M, Matsumoto K, Subhadhirasakul S, Takayama H, Aimi N, et al. A possible mechanism underlying corymine inhibition of glycine-induced chloride current in Xenopus oocytes. Eur J Pharmacol. 1998;348:271-277.
4. Larson AA, Beitz AJ. Glycine potentiates strychnine-induced convulsions: role of NMDA receptors. J Neurosci. 1988;8:3822-3826.
5. Williams K. Ifenprodil, a novel NMDA receptor antagonist: site and mechanism of action. Curr Drug Targets. 2001;2:285-298.
6. Koch HJ, Szecsey A, Haen E. NMDA-antagonism (Memantine): an alternative pharmacological therapeutic principle in Alzheimer's and vascular dementia. Curr Pharm Des. 2004;10: 253-259.
7. Tamminga C. Schizophrenia and glutamatergic transmission. Crit Rev Neurobiol. 1998;12:21-36.
8. Heresco-Levy U, Ermilov M, Shimoni J, Shapira B, Silipo G, Javitt DC. Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia. Am J Psychiat. 2002;159:480-482.
9. Schwartz BL, Hashtroudi S, Herting RL, Schwartz P, Deutsch SI. D-cycloserine enhances implicit memory in Alzheimer patients. Neurology. 1996;46:420-424.
10. Dingledine R, Borges K, Bowie D, Traynelis SF. The glutamate receptor ion channels. Pharmacol Rev. 1999;51:7-61.
11. Monyer H, Sprengel R, Schoepfer R, Herb A, Higuchi M, Lomeli H, et al. Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science. 1992;256:1217-1221.
12. Laube B, Kuhse J, Betz H. Evidence for a tetrameric structure of recombinant NMDA receptors. J Neurosci. 1998;18:2954-2961.
13. Hirai H, Kirsh J, Laube B, Betz H, Kuhse J. The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region. Proc Natl Acad Sci USA. 1996;93:6031-6036.
14. Ishii T, Moriyoshi K, Sugihara H, Sakurada K, Kadotani H, Yokoi M, et al. Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. J Biol Chem. 1993;268: 2836-2843.
15. Monaghan DT, Larsen H. NR1 and NR2 subunit contributions to N-Methy-D-aspartate rreceptor channel blocker pharmacology. J Pharmacol Exp Ther. 1997;280:614-620.
16. Williams K. Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol. 1993;44:851-859.
17. Hollmann M, Heinemann S. Cloned glutamate receptors. Ann Rev Neurosci. 1994;17:31-108.
18. Priestley T, Laughton P, Myers J, Le Bourdelles B, Kerby J, Whiting PJ. Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells. Mol Pharmacol. 1995;48: 841-848.
19. Woodward RM, Huettner JE, Guastella J, Keana JF, Weber E. In vitro pharmacology of ACEA-1021 and ACEA-1031: systemically active quinoxalinediones with high affinity and selectivity for N-methyl-D-aspartate receptor glycine sites. Mol Pharmacol. 1995;47:568-581.
20. Chazot PL. The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies. Curr Med Chem. 2004;11:389-396.
21. Myhrer T. Adverse psychological impact, glutamatergic dysfunction, and risk factors for Alzheimer's disease. Neurosci Biobehav Rev. 1998;23:131-139.
22. Tang YP, Wang H, Feng R, Kyin M, Tsien JZ. Differential effects of enrichment on learning and memory function in NR2B transgenic mice. Neuropharmacology. 2001;41:779-790.
23. Blanchet PJ, Konitsiotis S, Whittemore ER, Zhou ZL, Woodward RM, Chase TN. Differing effects of N-methyl-D-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl- tetrahydropyridine monkeys. J Pharmacol Exp Ther. 1999;290:1034-1040.
24. Blank T, Nijholt I, Teichert U, Kugler H, Behrsing H, Fienberg A, et al. The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-D-aspartate responses. Proc Natl Acad Sci USA. 1997;94:14859-14864.
25. Wilcox KS, Fitzsimonds RM, Johnson B, Dichter MA. Glycine regulation of synaptic NMDA receptors in hippocampal neurons. J Neurophysiol. 1996;76:3415-3424.
26. Supplisson S, Bergman C. Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes. J Neurosci. 1997;17:4580-4590.
27. Buller AL, Larson HC, Schneider BE, Beaton JA, Morrisett RA, Monaghan DT. The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition. J Neurosci. 1994;14:5471-5484.
28. Kew JN, Richards JG, Mutel V, Kemp JA. Development changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons. J Neurosci. 1998;18:1935-1943.
29. Masuko T, Kuno T, Kashiwagi K, Kusama T, Williams K, Igarashi K. Stimulatory and inhibitory properties of aminoglycoside antibiotics at N-methyl-D-aspartate receptors. J Pharmacol Exp Ther. 1999;290:1026-1033.
30. Durand GM, Bennett MV, Zukin RS. Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C. Proc Natl Acad Sci USA. 1993;90:6731-6735.
31. Durand GM, Gregor P, Zheng X, Bennett MV, Uhl GR, Zukin RS. Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C. Proc Natl Acad Sci USA. 1992;89:9359-9363.
32. Benveniste M, Mayer ML. Multiple effect of spermine on N-methyl-d-aspartic acid receptor responses of rat cultured hippocampal neurons. J Physiol (Lond). 1993;464:131-163.
33. McGurk FJ, Bennett VLM, Zukin SR. Polyamines potentiate response of N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Neurobiology. 1990;87:9971-9974.
34. Zhang L, Zheng X, Paupard MC, Wang AP, Santchi L, Friedman LK, et al. Spermine potentiation of recombinant N-methyl-D-aspartate receptors is affected by subunit composition. Proc Natl Acad Sci USA. 1994;91:10883-10887.
35. Leonard JP, Kelso SR. Apparent desensitization of NMDA responses in Xenopus oocytes involves calcium-dependent chloride current. Neuron. 1990;4:53-60.
36. Miledi R, Parker I. Chloride current induced by injection of calcium into Xenopus oocytes. J Physiol (Lond). 1984;357:173-183.
37. - channels in Xenopus oocytes. Pfleugers Archiv. 1995;429:820-824.
38. - channel. J Memb Biol. 1995;148:263-275.
39. Kleckner NW, Glazewski JC, Chen CC, Moscrip TD. Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action. J Pharmacol Exp Ther. 1999;289:886-894.
40. McIlhinney RA, Philipps E, Le Bourdelles B, Grimwood S, Wafford K, Sandhu S, et al. Assembly of N-methyl-D-aspartate (NMDA) receptors. Biochem Soc Trans. 2003;31:865-868.
41. Garcia-Gallo M, Renart J, Diaz-Guerra M. The NR1 subunit of the N-methyl-D-aspartate receptor can be efficiently expressed alone in the cell surface of mammalian cells and is required for the transport of the NR2A subunit. Biochem J. 2001;356:539-547.
42. Olney JW, Farber NB. Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry. 1995;52:998-1007.
43. Javitt DC, Zylberman I, Zukin SR, Heresco-Levy U, Lindenmayer JP. Amelioration of negative symptoms in schizophrenia by glycine. Am J Psychiatry. 1994;151:1234-1236.
44. Mohn AR, Gainetdinov RR, Caron MG, Koller BH. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell. 1999;98:427-436.