Glutathione S-transferase π protects serum depletion-induced cell death by inhibiting ASK1-MKK7-JNK pathway in the 293 cells

Acta Biochimica et Biophysica Sinica

Volumn 33, Issue 2, 2001, Pages 189-190

  Yin, Zhi Min ^a   Liu, Ai Hua ^a   Jiang, Yong ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Cell death; Glutathione S transferase; Mitogen activated protein kinases; Signal transduction; Stress

Indexed keywords

EID: 20444388731     PISSN: 05829879     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Biguet C, Wakasugi N, Mishal Z, Holmgren A, Chouaib S, Tursz T, Wakasugi H. Thioredoxin increases the proliferation of human B-cell lines through a protein kinase C-dependent mechanism. J Biol Chem, 1994, 269(46): 28865-28870
2. Tan P, Fuchs S Y, Chen A, Wu K, Gomez C, Ronai Z, Pan Z Q. Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha. Mol Cell, 1999, 3(4): 527-533
3. Powis G, Briehl M, Oblong J. Redox signalling and the control of cell growth and death. Pharmacol Ther, 1995, 68(1): 149-173
4. Chakraborti S, Chakraborti T. Oxidant-mediated activation of mitogen-activated protein kinases and nuclear transcription factors in the cardiovascular system: A brief overview. Cell Signal, 1998, 10(10): 675-683
5. Piette J, Piret B, Bonizzi G, Schoonbroodt S, Merville M P, Legrand-Poels S, Bours V. Multiple redox regulation in NF-kappaB transcription factor activation. Biol Chem, 1997, 378(11): 1237-1245
6. Wilhelm D, Bender K, Knebel A, Angel P. The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents. Mol Cell Biol, 1997, 17(8): 4792-4800
7. Boucher D M, Iannaccone P M. Overexpression of human glutathione S-transferase pi protects NIH 3T3 cells against (+/-) anti BPDE cytotoxicity but not tumor formation. Pathobiology, 1995, 63(4): 197-203
8. Baez S, Segura-Aguilar J, Widersten M, Johansson A S, Mannervik B. Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes. Biochem J, 1997, 324 (Pt 1): 25-28
9. Townsend A J, Fields W R, Haynes R L, Doss A J, Li Y, DoehmerJ, Morrow CS. Chemoprotective functions of glutathione S-transferases in cell lines induced to express specific isozymes by stable transfection. Chem Biol Interact, 1998, 111-112: 389-407
10. Morrow C S, Smitherman P K, Diah S K, Schneider E, Townsend A J. Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells. J Biol Chem, 1998, 273(32): 20114-20120
11. Jiang Y, Han J. p38 MAPK signal transduction pathway. Life Science, 1999, 11(3): 102-106
12. Jiang Y, Chen C, Li Z, Guo W, Gegner J A, Lin S, Han J. Characterization of the structure and function of a new mitogen-activated protein kinase (p38β). J Biol Chem, 1996, 271 (30): 17920-17926
13. Jiang Y. Progress on the study of signaling mechanism of endothelium stimulated by endotoxin. Natl J Chin Med, 1999, 79 (1): 76-78
14. Jiang Y, Liu A H, Huang Q B, Han J, Zhao K S. p38 MAPK signal is necessary for TNF-α gene expression in RAW264.7 cells stimulated by LPS. Acta Biochimica et Biophysica Sinica, 1999, 31(1): 9-15
15. Huang S, Jiang Y, Li Z, Nishda E, Mathias P, Lin S, Ulevitch R J et al. Apoptosis signaling pathway in T cells is composed of ICE/ Ced-3 family protease and MAP kinase 6b. Immunity, 1997, 6 (6): 739-749
16. Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science, 1997, 275(5296): 90-94
17. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J, 1998, 17(9): 2596-2606
18. Kanamoto T, Mota M, Takeda K, Rubin L L, Miyazono K, Ichijo H, Bazenet C E. Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons. Mol Cell Biol, 2000, 20(1): 196-204
19. 2-induced cell death via coordinated regulation of stress kinases. Cancer Res, 2000, 60: 4053-4057
20. Zhang L, Zhang L, Jiang Y, Zhao K S. Role of p38 protein kinase in heat-induced Raw cells apoptosis. Chin Med J, 2000, 113(4): 354-357
21. Chen Z, Seimiya H, Naito M, Mashima T, Kizaki A, Dan S, Imaizumi M et al. ASK1 mediates apoptotic cell death induced by genotoxic stress. Oncogene, 1999, 18(1): 173-180
22. Yang X, Khosravi-Far R, Chang H Y, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell, 1997, 89(7): 1067-1076
23. Adler V, Yin Z, Fuchs S Y, Benezra M, Rosario L, Tew K D, Pincus M R et al. Regulation of JNK signaling by GSTp. EMBO J, 1999, 18(5): 1321-1334
24. Alder V, Shaffer A, Kim J, Dolan L, Ronai Z. UV-irradiation and heat shock mediate JNK activation via alternate pathways. J Biol Chem, 1995, 270: 26071-26077