Effects of nutrients on the production of AK-111-81 macrolide antibiotic by Streptomyces hygroscopicus

Microbiological Research

Volumn 160, Issue 3, 2005, Pages 243-248

  Gesheva, V ^a   Ivanova, V ^a   Gesheva, R ^a  

^a INSTITUTE OF MICROBIOLOGY   (Bulgaria)

Author keywords

Nonpolyenic macrolide antibiotic; Nutrient effects; Streptomyces hygroscopicus

Indexed keywords

BIOSYNTHESIS; CARBON; FERMENTATION; GLUCOSE; GLYCEROL; IONS; NITROGEN; NUTRITION;

AMMONIUM SUCCINATE; BASAL FERMENTATION; LACTOSE;

ANTIBIOTICS;

GROWTH RATE; NUTRIENT AVAILABILITY;

STREPTOMYCES HYGROSCOPICUS;

EID: 20444373727     PISSN: 09445013     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micres.2004.06.005     Document Type: Article

References (26)

1. Y. Aharonowitz Nitrogen metabolite regulation of antibiotic biosynthesis Annu. Rev. Microbiol. 34 1980 209 234
2. Y. Aharonowitz, and A.L. Demain Carbon catabolite regulation of cephalosporin production in Streptomyces clavuligerus Antimicrob. Agents Chemother. 14 1978 159 164
3. S. Chatterjee, and L.C. Vining Nutrient utilization in actinomycetes. Induction of α-glucosidases in Streptomyces venezulae Can. J. Microbiol. 27 1981 639 645
4. J.R. Cheng, A. Fang, and A.L. Demain Effect of amino acids on rapamycin biosynthesis in Streptomyces hygroscopicus Appl. Microbiol. Biotechnol. 43 1995 1096 1098
5. S. Coisne, M. Bechet, and R. Blondeau Actinorhodin production by Streptomyces coelicolor A3(2) in iron-restricted media Lett. Appl. Microbiol. 28 1999 199 202
6. A.L. Demain, Y. Aharonowitz, and J.F. Martin Metabolite control of secondary biosynthetic pathways L.C. Vining Biochemistry and Genetic Regulation of Commercially Important Antibiotics 1983 Addison-Wesley London 49 67
7. J.L. Doull, and L.C. Vining Nutritional control of actinorhodin production of Streptomyces coelicolor A3(2); suppressive effect of nitrogen and phosphate Appl. Microbiol. Biotechnol. 32 1990 449 454
8. Georgieva-Borisova, J.Ch., 1974. Taxonomic characteristics of strain Actinomyces hygroscopicus B-255 and conditions for its antibiotic production. Ph. D. Thesis, Sofia.
9. V. Gesheva, V. Ivanova, and R. Gesheva Biological characteristics and antibiotic production of Streptomyces hygroscopicus strains Actinomycetes 5 1994 57 63
10. Gesheva, R.L., Ivanova, V.B., Saharieva, M., Rachev, R., Rusev, P.P., Popov, K.B., Tzvetkova, R.Ch., Belomusova, D.K., Sevrieva, V.S., Gushterova, A.G., Thrum, H., Schlegel, R., Kleinwachter, W., Schade, W., 1981. Bulgarian Patent No. 32,645.
11. R. Gesheva, P. Panajotov, M. Darakchieva, M. Naumova, H. Tsankov, M. Mladenov, and J. Karajova Actinomycetes antagonists of Fusarium graminearum schw., responsible for fusariosis of wheat Prilojna Mikrobiol. 7 1977 76 81
12. V. Ivanova, R. Gesheva, P. Panajotov, and D. Belomusova Isolation, purification and separation of polyether antibiotic complex from Streptomyces hygroscopicus 111-81 A. Toshkov Successes in Industrial and Infection Microbiology 1984 BAN Sofia 27 34
13. V. Ivanova, and R. Schlegel Structure elucidation of the antibiotic demalonylniphimycin by two-dimensial NMR techniques Actinomycetes 8 1998 1 9
14. A. Lebrihi, D. Lamsaif, G. Lefebvre, and P. Germain Effect of ammonium salts ions on spiramycin biosynthesis in Streptomyces ambofaciens Appl. Microbiol. Biotechnol. 37 1992 382 387
15. M.C. Lee, J. Kojima, and A.L. Demain Effect of nitrogen source on biosynthesis of rapamycin by Streptomyces hygroscopicus J. Ind. Microbiol. Biotechnol. 19 1997 83 86
16. C.M. Liu, L.E. McDaniel, and C.P. Schafferer Factors affecting the production of candicidin Antimicrob. Agents Chemother. 7 1975 196 202
17. J.F. Martin, and A.L. Demain Control of antibiotic biosynthesis Microbiol. Rev. 44 1980 230 251
18. V.N. Maximov Multifactorial Experiments in Biology 1980 Moscow State University Publ. Moscow
19. P. Moncheva, S. Danova, S. Antonova, and I. Ivanova Physiological role of extracellular proteases and Ca2+ in the differentiation processes and antibiotic formation by Streptomyces albogriseolus Antibiot. Chimiotherapia 42 1997 14 19
20. S. Omura, and J. Tanaka Biosynthesis of tylosin and its regulation by ammonium and phosphate H. Kleinkauf H. von Döhren H. Dormaner G. Nesmann Regulation of Secondary Metabolites 1986 VCH Publishers Inc. Berlin 306 332
21. S. Parekh, V.A. Vinci, and K.J. Strobel Improvement of microbial strains and fermentation processes Appl. Microbiol. Biotechnol. 54 2000 287 301
22. A. Pereda, K.G. Summers, D.L. Stassi, X. Ruan, and L. Katz The loading domain of the erythromycin polyketide synthase is not essential for erythromycin biosynthesis in Saccharopolyspora erytraea Microbiology 144 1998 543 553
23. S. Sanchez, and A.L. Demain Metabolic regulation of fermentation processes Enz. Microb. Technol. 31 2002 895 906
24. C.P. Smith, and K.F. Chater Cloning and transcriptional analysis of the entire glycerol utilization (gylABX) operon of Streptomyces coelicolor A3(2) and identification of a closely associated transcription unit Mol. Gen. Genet. 211 1988 129 137
25. S. Solivery, A. Mendosa, and M.E. Arias Effect of different nutrients on the production of polyene antibiotics PA-5 and PA-7 by Streptoverticillium sp. 43/16 in chemically defined medium Appl. Microbiol. Biotechnol. 28 1988 254 257
26. K.A. Vinogradova, N.P. Kirilova, Z.G. Sokolova, P.A. Nikolau, M.V. Shalgina, G.N. Skvortsova, and A.N. Polin Regulation of heliomycin biosynthesis by carbon sources Antibiot. Med. Technol. 30 1985 264 270