The multiple routes of MHC-I cross-presentation

Trends in Microbiology

Volumn 12, Issue 5, 2004, Pages 204-207

  Ramirez, Maria C ^a   Sigal, Luis J ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; PROTEASOME;

ANTIGEN PRESENTATION; CELL MEMBRANE; CELL TRANSPORT; CYTOSOL; ENDOPLASMIC RETICULUM; HISTOCOMPATIBILITY; MOLECULE; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; PROCESSING; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; REVIEW; TONOPLAST;

EID: 2042473501     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tim.2004.03.008     Document Type: Short Survey

References (25)

1. Townsend A., Bodmer H. Antigen recognition by class I-restricted T lymphocytes. Annu. Rev. Immunol. 7:1989;601-624
2. Sigal L.J., Rock K.L. Bone marrow-derived antigen-presenting cells are required for the generation of cytotoxic T lymphocyte responses to viruses and use transporter associated with antigen presentation (TAP)-dependent and - independent pathways of antigen presentation. J. Exp. Med. 192:2000;1143-1150
3. Sigal L.J., et al. Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen. Nature. 398:1999;77-80
4. Lenz L.L., et al. Requirements for bone marrow-derived antigen-presenting cells in priming cytotoxic T cell responses to intracellular pathogens. J. Exp. Med. 192:2000;1135-1142
5. York I.A., Rock K.L. Antigen processing and presentation by the class I major histocompatibility complex. Annu. Rev. Immunol. 14:1996;369-396
6. Pamer E., Cresswell P. Mechanisms of MHC class I-restricted antigen processing. Annu. Rev. Immunol. 16:1998;323-358
7. Norbury C.C., Sigal L.J. Cross priming or direct priming: is that really the question? Curr. Opin. Immunol. 15:2003;82-88
8. Gold M.C., et al. The murine cytomegalovirus immunomodulatory gene m152 prevents recognition of infected cells by M45-specific CTL but does not alter the immunodominance of the M45-specific CD8 T cell response in vivo. J. Immunol. 169:2002;359-365
9. Basta S., et al. Inhibitory effects of cytomegalovirus proteins US2 and US11 point to contributions from direct priming and cross-priming in induction of vaccinia virus-specific CD8(+) T cells. J. Immunol. 168:2002;5403-5408
10. Lizee G., et al. Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain. Nat. Immunol. 4:2003;1065-1073
11. Rock K.L., et al. Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science. 249:1990;918-921
12. Norbury C.C., et al. Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages. Immunity. 3:1995;783-791
13. Norbury C.C., et al. Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells. Eur. J. Immunol. 27:1997;280-288
14. Kovacsovics-Bankowski M., et al. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc. Natl. Acad. Sci. U. S. A. 90:1993;4942-4946
15. Pfeifer J.D., et al. Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature. 361:1993;359-362
16. Albert M.L., et al. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature. 392:1998;86-89
17. Ramirez M.C., Sigal L.J. Macrophages and dendritic cells use the cytosolic pathway to rapidly cross-present antigen from live, vaccinia-infected cells. J. Immunol. 169:2002;6733-6742
18. Kovacsovics-Bankowski M., Rock K.L. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science. 267:1995;243-246
19. Shen Z., et al. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J. Immunol. 158:1997;2723-2730
20. Houde M., et al. Phagosomes are competent organelles for antigen cross-presentation. Nature. 425:2003;402-406
21. Guermonprez P., et al. ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature. 425:2003;397-402
22. Ackerman A.L., et al. Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc. Natl. Acad. Sci. U. S. A. 100:2003;12889-12894
23. Garin J., et al. The phagosome proteome: insight into phagosome functions. J. Cell Biol. 152:2001;165-180
24. Gagnon E., et al. Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell. 110:2002;119-131
25. Reis e Sousa C., Germain R.N. Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J. Exp. Med. 182:1995;841-851