Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse

Neuron

Volumn 46, Issue 2, 2005, Pages 191-204

  Sahin, Mustafa ^a   Greer, Paul L ^a   Lin, Michael Z ^a   Poucher, Heather ^b   Eberhart, Johann ^c   Schmidt, Susanne ^d   Wright, Tracy M ^a   Shamah, Steven M ^a   O'Connell, Sinead ^c   Cowan, Christopher W ^a   Hu, Linda ^a   Goldberg, Jeffrey L ^e   Debant, Anne ^d   Corfas, Gabriel ^a   Krull, Catherine E ^b   Greenberg, Michael E ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

^d Centre National de la Recherche Scientifique   (France)

^e UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPHEXIN 1; EPHRIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; PROTEIN CDC42; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; GROWTH CONE; MOUSE; NERVE CELL; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 20244381549     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2005.01.030     Document Type: Article

References (24)

1. C.W. Cowan, Y.R. Shao, M. Sahin, S.M. Shamah, M.Z. Lin, P.L. Greer, S. Gao, E.C. Griffith, J.S. Brugge, and M.E. Greenberg Vav family GEFs link activated Ephs to endocytosis and axon guidance Neuron 46 2005 205 217
2. A. Debant, C. Serra-Pages, K. Seipel, S. O'Brien, M. Tang, S.H. Park, and M. Streuli The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains Proc. Natl. Acad. Sci. USA 93 1996 5466 5471
3. B.J. Dickson Molecular mechanisms of axon guidance Science 298 2002 1959 1964
4. J. Eberhart, M.E. Swartz, S.A. Koblar, E.B. Pasquale, and C.E. Krull EphA4 constitutes a population-specific guidance cue for motor neurons Dev. Biol. 247 2002 89 101
5. J. Eberhart, J. Barr, S. O'Connell, A. Flagg, M.E. Swartz, K.S. Cramer, K.W. Tosney, E.B. Pasquale, and C.E. Krull Ephrin-A5 exerts positive or inhibitory effects on distinct subsets of EphA4-positive motor neurons J. Neurosci. 24 2004 1070 1078
6. D.A. Feldheim, P. Vanderhaeghen, M.J. Hansen, J. Frisen, Q. Lu, M. Barbacid, and J.G. Flanagan Topographic guidance labels in a sensory projection to the forebrain Neuron 21 1998 1303 1313
7. J.G. Flanagan, and P. Vanderhaeghen The ephrins and Eph receptors in neural development Annu. Rev. Neurosci. 21 1998 309 345
8. A.B. Huber, A.L. Kolodkin, D.D. Ginty, and J.F. Cloutier Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance Annu. Rev. Neurosci. 26 2003 509 563
9. W.M. Jurney, G. Gallo, P.C. Letourneau, and S.C. McLoon Rac1-Mediated Endocytosis during Ephrin-A2- and Semaphorin 3A-Induced Growth Cone Collapse J. Neurosci. 22 2002 6019 6028
10. B. Knoll, and U. Drescher Src family kinases are involved in EphA receptor-mediated retinal axon guidance J. Neurosci. 24 2004 6248 6257
11. C.E. Krull A primer on using in ovo electroporation to analyze gene function Dev. Dyn. 229 2004 433 439
12. A. Meyer-Franke, M.R. Kaplan, F.W. Pfrieger, and B.A. Barres Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture Neuron 15 1995 805 819
13. Y. Minoshima, T. Kawashima, K. Hirose, Y. Tonozuka, A. Kawajiri, Y.C. Bao, X. Deng, M. Tatsuka, S. Narumiya, and W.S. May Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis Dev. Cell 4 2003 549 560
14. W.H. Moolenaar Bioactive lysophospholipids and their G protein-coupled receptors Exp. Cell Res. 253 1999 230 238
15. C.D. Nobes, and A. Hall Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia Cell 81 1995 53 62
16. H. Ogita, S. Kunimoto, Y. Kamioka, H. Sawa, M. Masuda, and N. Mochizuki EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells Circ. Res. 93 2003 23 31
17. A. Palmer, and R. Klein Multiple roles of ephrins in morphogenesis, neuronal networking, and brain function Genes Dev. 17 2003 1429 1450
18. P. Penzes, A. Beeser, J. Chernoff, M.R. Schiller, B.A. Eipper, R.E. Mains, and R.L. Huganir Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of Rho-GEF kalirin Neuron 37 2003 263 274
19. S.M. Shamah, M.Z. Lin, J.L. Goldberg, S. Estrach, M. Sahin, L. Hu, M. Bazalakova, R.L. Neve, G. Corfas, A. Debant, and M.E. Greenberg EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin Cell 105 2001 233 244
20. Q.L. Sun, J. Wang, R.J. Bookman, and J.L. Bixby Growth cone steering by receptor tyrosine phosphatase delta defines a distinct class of guidance cue Mol. Cell. Neurosci. 16 2000 686 695
21. L. Van Aelst, and C. D'Souza-Schorey Rho GTPases and signaling networks Genes Dev. 11 1997 2295 2322
22. F.P. van Horck, C. Weinl, and C.E. Holt Retinal axon guidance: novel mechanisms for steering Curr. Opin. Neurobiol. 14 2004 61 66
23. S. Wahl, H. Barth, T. Ciossek, K. Aktories, and B.K. Mueller Ephrin-A5 induces collapse of growth cones by activating rho and rho kinase J. Cell Biol. 149 2000 263 270
24. R.S. Winning, E.K. Ward, J.B. Scales, and G.K. Walker EphA4 catalytic activity causes inhibition of RhoA GTPase in Xenopus laevis embryos Differentiation 70 2002 46 55