Prognostic significance of allelic imbalance at the c-kit gene locus and c-kit overexpression by immunohistochemistry in pediatric osteosarcomas

Journal of Clinical Oncology

Volumn 23, Issue 10, 2005, Pages 2248-2255

  Entz Werlé, Natacha ^a   Marcellin, Luc ^b   Gaub, Marie Pierre ^b   Guerin, Eric ^b   Schneider, Anne ^b   Berard Marec, Perrine ^b   Kalifa, Chantal ^b   Brugiere, Laurence ^b   Pacquement, Helène ^b   Schmitt, Claudine ^b   Tabone, Marie Dominique ^b   Jeanne Pasquier, Corinne ^b   Terrier, Philippe ^b   Dijoud, Frédérique ^b   Oudet, Pierre ^b   Lutz, Patrick ^b   Babin Boilletot, Annie ^b  

^a HÔPITAL DE HAUTEPIERRE   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; METHOTREXATE; STEM CELL FACTOR; TYROSINE KINASE RECEPTOR; DNA; STEM CELL FACTOR RECEPTOR;

ADOLESCENT; ADULT; ALLELIC IMBALANCE; ARTICLE; C KIT GENE; CHILD; CHILDHOOD CANCER; CONTROLLED STUDY; DNA EXTRACTION; DRUG MEGADOSE; FEMALE; GENE; GENE AMPLIFICATION; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; ONCOGENE; OSTEOSARCOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; BIOSYNTHESIS; BONE TUMOR; CHROMOSOME 4; COHORT ANALYSIS; GENE EXPRESSION PROFILING; GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY; PRESCHOOL CHILD; SURVIVAL;

ADOLESCENT; ADULT; ALLELIC IMBALANCE; BONE NEOPLASMS; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 4; COHORT STUDIES; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; OSTEOSARCOMA; POLYMERASE CHAIN REACTION; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-KIT; SURVIVAL ANALYSIS;

EID: 20244374843     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.03.119     Document Type: Article

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