Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib

Journal of Biological Chemistry

Volumn 280, Issue 15, 2005, Pages 14918-14922

  Lloyd, David B ^a   Lira, Maruja E ^a   Wood, Linda S ^a   Durham, L Kathryn ^a   Freeman, Thomas B ^a   Preston, Gregory M ^a   Qiu, Xiayang ^a   Sugarman, Eliot ^a   Bonnette, Peter ^a   Lanzetti, Anthony ^a   Milos, Patrice M ^a   Thompson, John F ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR SYSTEM; DISEASES; GENES; GENETIC ENGINEERING; MEDICAL IMAGING; PROTEINS;

CARDIOVASCULAR DISEASES; CHOLESTERYL ESTER TRANSFER PROTEIN (CETP); GENE ENCODING; NUCLEOTIDES;

ESTERS;

ATORVASTATIN; CHOLESTEROL ESTER TRANSFER PROTEIN; GLUTAMINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PROLINE; TORCETRAPIB;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HAPLOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MASS; PHASE 2 CLINICAL TRIAL; POPULATION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ADULT; AGED; CARDIOVASCULAR DISEASES; CARRIER PROTEINS; CELL LINE; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL, HDL; CRYSTALLOGRAPHY, X-RAY; DNA, COMPLEMENTARY; FEMALE; GENOME, HUMAN; GLUTAMINE; GLYCOPROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; LIPOPROTEINS, HDL; MALE; MIDDLE AGED; MODELS, MOLECULAR; MUTATION, MISSENSE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROLINE; PROTEIN BINDING; PROTEIN CONFORMATION; QUINOLINES; TRANSCRIPTION, GENETIC;

EID: 20244371692     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500523200     Document Type: Article

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