2,3-Diaminopyridine as a platform for designing structurally unique nonpeptide bradykinin B1 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 9, 2005, Pages 2385-2388

  Feng, Dong Mei ^a   Wai, Jenny M ^a   Kuduk, Scott D ^a   Ng, Christina ^a   Murphy, Kathy L ^a   Ransom, Richard W ^a   Reiss, Duane ^a   Chang, Raymond S L ^a   Harrell, Charles M ^a   MacNeil, Tanya ^a   Tang, Cuyue ^a   Prueksaritanont, Thomayant ^a   Freidinger, Roger M ^a   Pettibone, Douglas J ^a   Bock, Mark G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

2,3 Diaminopyridine; Antagonists; Bradykinin B1; Receptor

Indexed keywords

BRADYKININ B1 RECEPTOR ANTAGONIST; PYRIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG HALF LIFE; DRUG POTENCY; DRUG STRUCTURE; FEMALE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

EID: 20244367933     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.077     Document Type: Article

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