A carbohydrate fraction, AIP1, from Artemisia iwayomogi down-regulates Fas gene expression and suppresses apoptotic death of the thymocytes induced by 2,3,7,8-tectrachlorodibenzo-p-dioxin

Biotechnology Letters

Volumn 27, Issue 4, 2005, Pages 253-257

  Ji, Hee Jung ^a   Yeo, Hee Kyoung ^a   Lee, Nam Hee ^a   Hwang, Jung Suk ^a   Koo, Kyung Ah ^a   Cheong, Seon Woo ^b   Park, Joo Hung ^b   Oh, Gap Soo ^b   Yoon, Chun Sik ^b   Youn, Hyun Joo ^a  

^a Inje University   (South Korea)

^b Changwon National University   (South Korea)

Author keywords

Apoptosis; Artemisia; Dioxin; Fas; Thymotoxicity

Indexed keywords

CELL CULTURE; GENES;

APOPTOSIS; CARBOHYDRATE FRACTION; GENE EXPRESSION; THYMOCYTES;

CARBOHYDRATES;

2,3,7,8 TETRABROMODIBENZO 4 DIOXIN; 2,3,7,8-TETRABROMODIBENZO-4-DIOXIN; CARBOHYDRATE; DIOXIN; FAS ANTIGEN; FAS PROTEIN, MOUSE; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL; APOPTOSIS; ARTEMISIA; ARTICLE; C57BL MOUSE; CELL CULTURE; CELL SURVIVAL; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG INTERACTION; FEMALE; METABOLISM; MOUSE; PHYSIOLOGY; THYMUS;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; ARTEMISIA; CARBOHYDRATES; CELL SURVIVAL; CELLS, CULTURED; DIOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG INTERACTIONS; FEMALE; MICE; MICE, INBRED C57BL; RECEPTORS, TUMOR NECROSIS FACTOR; THYMUS GLAND;

ARTEMISIA; ARTEMISIA IWAYOMOGI;

EID: 20144371842     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10529-004-8294-2     Document Type: Article

References (11)

1. HA Chapman RJ Riese GP Shi 1997 Emerging roles for cysteine protease in human Annu. Rev. Physiol. 59 63 88
2. S Galande LA Dickinson IS Mian M Sikorska T Kohwi-Shigematsu 2001 SATB1 cleavage by caspase 6 disrupts PDZ domain-mediated dimerization, causing detachment from chromatin early in T-cell apoptosis Mol. Cell Biol. 16 5591 5604
3. JS Hwang HK Chung EK Bae AY Lee HJ Ji DW Park HJ Jung CW Cho HJ Choi DS Lee KR Lee HJ Youn 2003 The polysaccharide fraction AIP1 from Artemisia iwayomogi suppresses apoptotic death of the mouse spleen cells in culture Arch. Pharm. Res. 26 294 300
4. AB Kamath I Camacho PS Nagarkatti M Nagarkatti 1999 Role of Fas and Fas ligand interactions in 2,3,7,8-tetra chlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity: increased resistance of thymocytes from Fas-deficient (lpr) and Fas ligand-defective (gld) mice to TCDD-induced toxicity Toxicol. Appl. Pharmacol. 160 141 155
5. NI Kerkvliet 2002 Recent advances in understanding the mechanisms of TCDD immunotoxicity Int. Immunopharm. 2 277 291
6. KL King JA Cidlowski 1998 Cell cycle regulation and apoptosis Annu. Rev. Physiol. 60 60 117
7. KA Koo JW Kwak KR Lee OP Zee ER Woo HK Park HJ Youn 1994 Antitumor and immuno-modulating activities of the polysaccharide fractions from Artemisia selengensis and Artemisia iwayomogi Arch. Pharm. Res. 17 371 374
8. G Kroemer L Bosca N Zamzami P Merchetti S Hortelano AC Martinez 1997 Detection of apoptosis and apoptosis-associated alterations I Lefkovits Immunology Methods Manual Academic Press San Diego 1111 1125
9. K Kuo S Hsu Y Li W Lin L Liu L Chang C Lin C Lin H Sheu 2000 Anticancer activity evaluation of the Solanum glycol alkaloid solamargine; triggering apoptosis in human hepatoma cells Biochem. Pharmacol. 60 1865 1873
10. T Lindsten AJ Ross A King W Zong JC Rathmell HA Shiels E Ulrich KG Waymire P Mahar K Frauwirth Y Chen M Wei VM Eng DM Adelman MC Simon A Ma JA Golden G Evan SJ Korsmeyer GR MacGregor CB Thompson 2000 The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues Mol. Cell 6 1389 1399
11. S Nagata P Golstein 1995 The Fas death factor Science 267 1449 1456