Isosteric ramatroban analogs: Selective and potent CRTH-2 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 6, 2005, Pages 1749-1753

  Robarge, Michael J ^a   Bom, David C ^a   Tumey, L Nathan ^a   Varga, Norbert ^a   Gleason, Elizabeth ^a   Silver, Daniel ^a   Song, Jianping ^a   Murphy, Steven M ^a   Ekema, George ^a   Doucette, Chris ^a   Hanniford, Doug ^a   Palmer, Marc ^a   Pawlowski, Gary ^a   Danzig, Joel ^a   Loftus, Margaret ^a   Hunady, Karen ^a   Sherf, Bruce A ^a   Mays, Robert W ^a   Stricker Krongrad, Alain ^a   Brunden, Kurt R ^a   Harrington, John J ^a   Bennani, Youssef L ^a   more..

^a ATHERSYS INC   (United States)

Author keywords

Asthma; CRTH 2; Prostaglandin D2; Ramatroban

Indexed keywords

CHEMOATTRACTANT; CHEMOATTRACTANT RECEPTOR HOMOLOGOUS MOLECULE EXPRESSED ON TH2 CELL ANTAGONIST; RAMATROBAN; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ARTICLE; BASOPHIL; CELL TYPE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; EOSINOPHIL; HUMAN; HUMAN CELL; TH2 CELL;

EID: 20044385221     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.12.055     Document Type: Article

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15. Further work to be published soon