Synthesis of O-(3-[18F]Fluoropropyl)-L-tyrosine (L-[ 18F]FPT) and its biological evaluation in 9L tumor bearing rat

Bulletin of the Korean Chemical Society

Volumn 26, Issue 1, 2005, Pages 91-96

  Moon, Byung Seok ^a   Kim, Sang Wook ^a   Lee, Tae Sup ^a   Ahn, Soon Hyuk ^a   Lee, Kyo Chul ^a   An, Gwang Il ^a   Yang, Seung Dae ^a   Chi, DaeYoon ^b   Choi, Chang Woon ^a   Lim, Sang Moo ^a   Chun, Kwon Soo ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b Inha University   (South Korea)

Author keywords

O (2 18F Fluoroethyl) L tyrosine (L 18F FET); O (3 18F Fluoropropyl) L tyrosine (L 18F FPT); PET; Tumor imaging

Indexed keywords

AMINO ACID; FLUORINE 18; O (2 FLUOROETHYL)TYROSINE F 18; O (3 FLUOROPROPYL)TYROSINE F 18; O [3 (4 TOLUENESULFONYLOXYPROPYL)] N (TERT BUTOXYCARBONYL)TYROSINE METHYL ESTER; TRACER; TYROSINE METHYL ESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG MUSCLE LEVEL; DRUG PURITY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MALE; NONHUMAN; PARTITION COEFFICIENT; POSITRON EMISSION TOMOGRAPHY; RADIOISOTOPE DECAY; RADIOISOTOPE DISTRIBUTION; RAT; TUMOR;

EID: 20044382414     PISSN: 02532964     EISSN: None     Source Type: Journal    
DOI: 10.5012/bkcs.2005.26.1.091     Document Type: Conference Paper

References (18)

1. Rigo, P.; Paulus, P.; Kaschten, B. J.; Hustinx, R.; Bury, T.; Jerusalem, G.; Benoit, T.; Foidart-Willems, J. Eur. J. Nucl. Med. 1996, 23, 1641-1674.
2. Shreve, P. D.; Anzai, Y.; Wahl, R. L. Radiographics 1999, 19, 61-77.
3. Weber, W. A.; Wester, H. J.; Grosu, A. L.; Herz, M.; Dzewas, B.; Feldmann, H. J.; Molls, M.; Stocklin, G.; Schwaiger, M. Eur. J. Nucl. Med. 2000, 27, 542-549.
4. Wester, H. J.; Herz, M.; Weber, W.; Heiss, P.; Senekowitsch-Schmidtke, R.; Schwaiger, M.; Stocklin, G. J. Nucl. Med. 1999, 40, 205-212.
5. Heiss, P.; Mayer, S.; Herz, M.; Wester, H. J.; Schwaiger, M.; Senekowitsch-Schmidtke, R. J. Nucl. Med. 1999, 40, 1367-1373.
6. Shoup, T. M.; Olson, J.; Hoffman, J. M.; Votaw, J.; Eshima, D.; Eshima, L.; Camp, V. M.; Stabin, M.; Votaw, D.; Goodman, M. M. J. Nucl. Med. 1999, 40, 331-338.
7. Wester, H. J.; Herz, M.; Senekowitsch-Schmidtke, R.; Schwaiger, M.; Stocklin, G.; Hamacher, K. Nucl. Med. Biol. 1999, 26, 259-265.
8. Kubota, K.; Ishiwata, K.; Kubota, R.; Yamada, S.; Takahashi, J.; Abe, Y.; Fukuda, H.; Ido, T. J. Nucl. Med. 1996, 37, 320-325.
9. Hustins, R.; Lemaire, C.; Jerusalem, G.; Moreau, P.; Cataldo, D.; Duysinx, B.; Aerts, J.; Fassotte, M. F.; Foidart, J.; Luxen, A. J. Nucl. Med. 2003, 44, 533-539.
10. Shikano, N.; Kawai, D.; Flores, L. G.; Nishii, R.; Kubota, N.; Ishikawa, N.; Kubodera, A. J. Nucl. Med. 2003, 44, 625-631.
11. Inoue, T.; Tomiyoshi, K.; Higuichi, T.; Ahmed, K.; Sarwar, M.; Aoyagi, K.; Amano, S.; Alyafei, S.; Zhang, H.; Endo, K. J. Nucl. Med. 1998, 39, 663-667.
12. Langen, K. J.; Muhlensiepen, H.; Holschbach, M.; Hautzel, H.; Jansen, P.; Coenen, H. H. J. Nucl. Med. 2000, 41, 1250-1255.
13. Chen, J. C.; Chang, S. M.; Hsu, F. Y.; Wang, H. E.; Liu, R. S. Appl. Radiat. Isot. 2004, 61, 887-891.
14. Tang, G.; Wang, M.; Tang, X.; Luo, L.; Gan, M. Nucl. Med. Biol. 2003, 30, 733-739.
15. Tang, G.; Tang, X.; Wang, M.; Luo, L.; Gan, M. Appl. Radiat. Isot. 2003, 58, 685-689.
16. Tang, G.; Tang, X.; Wang, M.; Luo, L.; Gan, M. Appl. Radiat. Isot. 2004, 60, 27-32.
17. Lee, K. C.; Lee, S. Y.; Choe, Y. S.; Chi, D. Y. Bull. Korean Chem. Soc. 2004, 25, 1225-1230.
18. Langen, K. J.; Jarosch, M.; Muhlensiepen, H.; Hamacher, K.; Broer, S.; Jansen, P.; Zilles, K.; Coenen, H. H. Nucl. Med. Biol. 2003, 30, 501-508.