Metabolic stability of [18F]fluoroalkylbiphenyls

Bulletin of the Korean Chemical Society

Volumn 25, Issue 8, 2004, Pages 1225-1230

  Kyo, Chul Lee ^a,c   Lee, Sang Yoon ^b,d   Yearn, Seong Choe ^b   Dae, Yoon Chi ^a  

^a Inha University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Korea Institute of Radiation and Medical Science   (South Korea)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fluorine 18; Fluoroalkyl; Fluoroalkylaromatics; Metabolism study; PET tracer

Indexed keywords

4 (2 FLUOROETHYL)BIPHENYL; 4 (2 FLUOROETHYL)BIPHENYL F 18; 4 (3 FLUOROPROPYL)BIPHENYL; 4 (3 FLUOROPROPYL)BIPHENYL F 18; 4 FLUOROMETHYLBIPHENYL; 4 FLUOROMETHYLBIPHENYL F 18; BIPHENYL DERIVATIVE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG METABOLISM; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HYDROBORATION; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; NONHUMAN; RAT; SERUM;

EID: 4944220217     PISSN: 02532964     EISSN: None     Source Type: Journal    
DOI: 10.5012/bkcs.2004.25.8.1225     Document Type: Article

References (27)

1. Raichle, M. E. Ann. Rev. Neurosci. 1983, 6, 249.
2. Lee, K. C.; Chi, D. Y. J. Org. Chem. 1999, 64, 8576.
3. Kim, D. W.; Song, C. E.; Chi, D. Y. J. Am. Chem. Soc. 2002, 124, 10278.
4. Kim, D. W.; Choe, Y. S.; Chi, D. Y. Nucl. Med. Biol. 2003, 30, 345.
5. Chi, D. Y.; Kilbourn, M. R.; Katzenellenbogen, J. A.; Brodack, J. W.; Welch, M. J. Appl. Radia., Isot. 1986, 37, 1173.
6. Yu, K. H.; Park, J. H.; Yang, S. D. Bull. Korean Chem. Soc. 2004, 25, 506.
7. Oh, S. J.; Choe, Y. S.; Kim, S. E.; Choi, Y.; Lee, K. H.; Kim, B.-T. Bull. Korean Chem. Soc. 2000, 21, 1162.
8. Mach, R. H.; Scripko, J. G.; Ehrenkaufer, R. L.; Morton, T. E. J. Labelled Compd. Radiopharm. 1991, 30, 154.
9. Haroutounian, S. A.; DiZio, J. P.; Katzenellenbogen, J. A. J. Org. Chem. 1991, 56, 4993.
10. Ng, J. S.; Katzenellenbogen, J. A.; Kilbourn, M. R. J. Org. Chem. 1981, 46, 2520.
11. Barrio, J. R.; Satyamurthy, N.; Ku, H.; Phelps, M. E. J. Chem. Soc., Chem. Commun. 1983, 443.
12. Choe, Y. S.; Song, D. H.; Lee, K.-J.; Kim, S. E.; Choi, Y.; Lee, K. H.; Kim, B.-T.; Oh, S. J.; Chi, D. Y. Appl. Radiat. Isot. 1998, 49, 73.
13. Petric, A.; Barrio, J. R.; Namavari, M.; Huang, S. C.; Satyamurthy, N. Nucl. Med. Biol. 1999, 26, 529.
14. Gerdes, J. M.; Keil, R. N.; Shulgin, A. T.; Mathis, C. A. J. Fluorine Chem. 1996, 78, 121.
15. Lee, K. C.; Moon, B. S.; Lee, J. H.; Chung, K.-H.; Katzenellenbogen, J. A.; Chi, D. Y. Bioorg. Med. Chem. 2003, 11, 3649.
16. Lee, B. C.; Paik, J.-Y.; Chi, D. Y.; Lee, K.-H.; Choe, Y. S. Bioconjugate Chem. 2004, 15, 104.
17. Kim, H. W.; Jeong, J. M.; Lee, Y.-S.; Chi, D. Y.; Chung, K.-H.; Lee, D. S.; Chung, J.-K.; Lee, M. C. Appl Radiat. Isot. 2004, 61, in web.
18. Oh, S. J.; Moszidanowski, C.; Chi, D. Y.; Kim, J. Y.; Kang, S. H.; Ryu, J. S.; Yeo, J. S.; Moon, D. H. Nucl. Med. Biol. 2004, 30, in print.
19. de Paulis, T.; Kumar, Y.; Johansson, L.; Rämsby, S.; Florvall, L.; Hall, H.; Ängeby-Möller, K.; Ögren, S. J. Med. Chem. 1985, 28, 1263.
20. de Paulis, T. Curr. Pharm. Design 2003, 9, 673.
21. Mukherjee, J.; Yang, Z.-y.; Das, M. K.; Brown, T. Nucl. Med. Biol. 1995, 22, 283.
22. Schmidt, D. E.; Votaw, J. R.; Kessler, R. M.; de Paulis, T. J. Pharm. Sci. 1994, 83, 305.
23. Lee, B. S.; Chu, S.; Lee, K. C.; Lee, B.-S.; Chi, D. Y.; Kim, S. E.; Choe, Y. S.; Song, Y. S.; Jin, C. Bioorg. Med. Chem. 2003, 11, 4949.
24. Lee, S.-Y.; Choe, Y. S.; Kim, D. H.; Park, B.-N.; Kim, S. E.; Choi, Y.; Lee, K.-H.; Lee, J.; Kim, B.-T. Nucl. Med. Biol. 2001, 25, 391.
25. Chen, P.; Kilts, C. D.; Camp, V. M.; Ely, T. D.; Malveaux, E.; Votaw, J.; Hoffman, J. M.; Goodman, M. M. J. Labelled Compd. Radiopharm. 1999, 42, S324.
26. Welch, M. J.; Katzenellenbogen, J. A.; Mathias, C. J.; Brodack, J. W.; Carlson, K. E.; Chi, D. Y.; Dence, C. S.; Kilbourn, M. R.; Perlmutter, J. S.; Raichle, M. E.; Ter-Pogossian, M. M. Nucl. Med. Biol. 1988, 15, 83.
27. Williams, D. A. Drug Metabolism in Principle of Medicinal Chemistry; Foye, W. O., Ed.; Lea & Febiger. Philadelphia, 1981; pp 95-103.