In vitro antifungal properties, structure-activity relationships and studies on the mode of action of N-phenyl, N-aryl, N-phenylalkyl maleimides and related compounds

Arzneimittel-Forschung/Drug Research

Volumn 55, Issue 2, 2005, Pages 123-132

  López, Silvia N ^a   Castelli, María V ^a   De Campos, Fátima ^b   Corrêa, Rogerio ^b   Cechinel Filho, Valdir ^b   Yunes, Rosendo A ^c   Zamora, Miguel A ^d   Enriz, Ricardo D ^d   Ribas, Juan C ^e   Furlán, Ricardo L E ^a   Zacchino, Susana A ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

^c FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^d Bioquim y Farmacia   (Argentina)

^e UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

(1,3) D Glucan synthase; Antifungal compounds; Chitin synthase; Fungal cell wall; Maleimides, in vitro anti fungal activity, structure activity relationship studies, synthesis

Indexed keywords

1,3 BETA GLUCAN SYNTHASE; AROMATIC HYDROCARBON; CARBON; CHITIN SYNTHASE; MALEIMIDE DERIVATIVE; N PHENYLPROPYL 3,4 DICHLOROMALEIMIDE; NITROGEN; PHENYL GROUP; PHENYLALKYLAMINE; POLYMER; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CATALYSIS; CELL WALL; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; FUNGAL CELL; IN VITRO STUDY; INHIBITION KINETICS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STANDARDIZATION; STRUCTURE ACTIVITY RELATION; YEAST;

EID: 20044366886     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296833     Document Type: Article

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