The effects of dehydroaltenusin, a novel mammalian DNA polymerase α inhibitor, on cell proliferation and cell cycle progression

Biochimica et Biophysica Acta - General Subjects

Volumn 1674, Issue 2, 2004, Pages 193-199

  Murakami Nakai, Chikako ^a   Maeda, Naoki ^a   Yonezawa, Yuko ^a   Kuriyama, Isoko ^a   Kamisuki, Shinji ^b   Takahashi, Shunya ^c   Sugawara, Fumio ^b   Yoshida, Hiromi ^a   Sakaguchi, Kengo ^b   Mizushina, Yoshiyuki ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

Cell cycle arrest; Cell growth inhibition; Dehydroaltenusin; DNA polymerase ; Enzyme inhibitor; Human cancer cell; Lipid bilayers of liposomes

Indexed keywords

CYCLIN A; CYCLIN E; DEHYDROALTENUSIN; DNA DIRECTED DNA POLYMERASE ALPHA; ENZYME INHIBITOR; HYDROXYUREA; LIPOSOME; NOCODAZOLE; UNCLASSIFIED DRUG; BENZOPYRAN DERIVATIVE; DNA DIRECTED DNA POLYMERASE BETA;

ANALYTIC METHOD; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL MEMBRANE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; LD 50; LIPID BILAYER; MOLECULAR INTERACTION; MOLECULAR MODEL; PRIORITY JOURNAL; ANIMAL; CELL DIVISION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DNA REPLICATION; DOSE RESPONSE; DRUG ANTAGONISM; METABOLISM;

ACREMONIUM SP.; FUNGI; MAMMALIA;

ANIMALS; BENZOPYRANS; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; DNA POLYMERASE I; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; LIPID BILAYERS; LIPOSOMES; MOLECULAR STRUCTURE;

EID: 19944431684     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2004.06.016     Document Type: Article

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