Childhood-onset growth hormone deficiency, cognitive function and brain N-acetylaspartate

Psychoneuroendocrinology

Volumn 30, Issue 4, 2005, Pages 357-363

  Sytze Van Dam, P ^a,d   De Winter, Channa F ^a   De Vries, Rehana ^a   Van Der Grond, Jeroen ^a   Drent, Madeleine L ^b   Lijffijt, Marijn ^c   Leon Kenemans, J ^c   Aleman, André ^c   De Haan, Edward H F ^c   Koppeschaar, Hans P F ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d ONZE LIEVE VROUWE GASTHUIS   (Netherlands)

Author keywords

Cognitive function; Growth hormone deficiency; N Acetylaspartate; Neuronal integrity

Indexed keywords

CHOLINE; GROWTH HORMONE; N ACETYLASPARTIC ACID;

ADOLESCENT; ADULT; ARTICLE; ATTENTION; BODY HEIGHT; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; GROWTH HORMONE DEFICIENCY; HORMONAL THERAPY; HUMAN; MALE; MEMORY; MENTAL FUNCTION; NEUROPSYCHOLOGICAL TEST; ONSET AGE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PSYCHOLOGIC TEST; READING; RECALL; SCORING SYSTEM; VERBAL MEMORY;

ADOLESCENT; ADULT; AGE OF ONSET; AGING; ASPARTIC ACID; BRAIN; BRAIN CHEMISTRY; CHOLINE; COGNITION; COGNITION DISORDERS; FEMALE; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NEURONS; NEUROPSYCHOLOGICAL TESTS;

EID: 19944431594     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2004.10.002     Document Type: Article

References (33)

1. D. Abbott, D. Rotnem, M. Genel, and D.J. Cohen Cognitive and emotional functioning in hypopituitary short-statured children Schizophr. Bull. 8 1982 310 319
2. A. Adem, S.S. Jossan, R. d'Argy, P.G. Gillberg, A. Nordberg, B. Winblad, and V. Sara Insulin-like growth factor 1 (IGF-1) receptors in the human brain: quantitative autoradiographic localization Brain Res. 503 1989 299 303
3. A. Aleman, H.J. Verhaar, E.H.F. de Haan, W. de Vries, M.M. Samson, M.L. Drent, E.A. van der Veen, and H.P.F. Koppeschaar Insulin-like growth factor-I and cognitive function in healthy older men J. Clin. Endocrinol. Metab. 84 1999 471 475
4. A. Aleman, W. de Vries, E.H.F. de Haan, H.J. Verhaar, M.M. Samson, and H.P.F. Koppeschaar Age-sensitive cognitive function, growth hormone, and insulin-like growth factor 1 plasma levels in healthy older men Neuropsychobiology 41 2000 73 78
5. O. Almqvist, M. Thoren, M. Saaf, and O. Eriksson Effects of growth hormone substitution on mental performance in adults with growth hormone deficiency: a pilot study Psychoneuroendocrinology 11 1986 347 352
6. L.J. Ball, G.B. Bisher, and S.J. Birge A simple test of central processing speed: an extension of the short blessed test J. Am. Geriatr. Soc. 47 1999 1359 1363
7. H.B. Baum, L. Katznelson, J.C. Sherman, B.M. Biller, D.L. Hayden, D.A. Schoenfeld, K.E. Cannistraro, and A. Klibanski Effects of physiological growth hormone (GH) therapy on cognition and quality of life in patients with adult-onset GH deficiency J. Clin. Endocrinol. Metab. 83 1998 3184 3189
8. B. Bulow, L. Hagmar, P. Orbaek, K. Osterberg, and E.M. Erfurth High incidence of mental disorders, reduced mental well-being and cognitive function in hypopituitary women with GH deficiency treated for pituitary disease Clin. Endocrinol. (Oxf) 56 2002 183 193
9. P. Burman, and J.B. Deijen Quality of life and cognitive function in patients with pituitary insufficiency Psychother. Psychosom. 67 1998 154 167
10. P. Burman, J. Hetta, L. Wide, J.E. Mansson, R. Ekman, and F.A. Karlsson Growth hormone treatment affects brain neurotransmitters and thyroxine Clin. Endocrinol. Oxf. 44 1996 319 324
11. P.V. Carroll, E.R. Christ, B.A. Bengtsson, L. Carlsson, J.S. Christiansen, D. Clemmons, R. Hintz, K. Ho, Z. Laron, P. Sizonenko, P.H. Sonksen, T. Tanaka, and M. Thorne Growth hormone deficiency in adulthood and the effects of growth hormone replacement: a review J. Clin. Endocrinol. Metab. 83 1998 382 395
12. J.R. Castro, J.A. Costoya, R. Gallego, A. Prieto, V.M. Arce, and R. Señarís Expression of growth hormone receptor in the human brain Neurosci. Lett. 281 2000 147 150
13. M. Dattani, and M. Preece Growth hormone deficiency and related disorders: insights into causation, diagnosis, and treatment Lancet 363 2004 1977 1987
14. M. Degerblad, O. Almqvist, R. Grunditz, K. Hall, L. Kaijser, E. Knutsson, H. Ringertz, and M. Thoren Physical and psychological capabilities during substitution therapy with recombinant growth hormone in adults with growth hormone deficiency Acta Endocrinol. Copenh. 123 1990 185 193
15. J.B. Deijen, H. de Boer, G.J. Blok, and E.A. Van der Veen Cognitive impairments and mood disturbances in growth hormone deficient men Psychoneuroendocrinology 21 1996 313 322
16. J.B. Deijen, H. de Boer, and E.A. Van der Veen Cognitive changes during growth hormone replacement in adult men Psychoneuroendocrinology 23 1998 45 55
17. J.M. Ferro, and S. Madureira Age-related white matter changes and cognitive impairment J. Neurol. Sci. 203-204 2002 221 225
18. J.O. Johansson, G. Larson, M. Andersson, A. Elmgren, L. Hynsjo, A. Lindahl, P.A. Lundberg, O.G. Isaksson, S. Lindstedt, and B.A. Bengtsson Treatment of growth hormone-deficient adults with recombinant human growth hormone increases the concentration of growth hormone in the cerebrospinal fluid and affects neurotransmitters Neuroendocrinology 61 1995 57 66
19. J.L. Kenemans Split second sequential selective activation in human secondary visual cortex J. Cogn. Neurosci. 14 2002 48 61
20. J.L. Kenemans, F.T. Smulders, and A. Kok Selective processing of two-dimensional visual stimuli in young and old subjects: electrophysiological analysis Psychophysiology 32 1995 108 120
21. J.H. Kranzler, A.L. Rosenbloom, V. Martinez, and J. Guevara Aguirre Normal intelligence with severe insulin-like growth factor I deficiency due to growth hormone receptor deficiency: a controlled study in a genetically homogeneous population J. Clin. Endocrinol. Metab. 83 1998 1953 1958
22. Z. Lai, P. Roos, O. Zhai, Y. Olsson, K. Fholenhag, C. Larsson, and F. Nyberg Age-related reduction of human growth hormone-binding sites in the human brain Brain Res. 621 1993 260 266
23. M. le Greves, P. Steensland, P. le Greves, and F. Nyberg Growth hormone induces age-dependent alteration in the expression of hippocampal growth hormone receptor and N-methyl-d-aspartate receptor subunits gene transcripts in male rats Proc. Natl Acad Sci. USA 99 2002 7119 7123
24. M.D. Lezak Neuropsychological assessment 1995 Oxford University Press New York
25. M. Lijffijt, P.S. Van Dam, J.L. Kenemans, H.P. Koppeschaar, W.R. de Vries, M.L. Drent, A. Wittenberg, and C. Kemner Somatotropic-axis deficiency affects brain substrates of selective attention in childhood-onset growth hormone deficient patients Neurosci. Lett. 353 2003 123 126
26. H.E. Nelson The National Adult Reading Test (NART): test manual 1982 NFER Nelson Windsor, UK
27. H. Oertel, H.J. Schneider, G.K. Stalla, F. Holsboer, and J. Zihl The effect of growth hormone substitution on cognitive performance in adult patients with hypopituitarism Psychoneuroendocrinology 29 2004 839 850
28. K.A. Peace, S.M. Orme, S.J. Padayatty, H.P. Godfrey, and P.E. Belchetz Cognitive dysfunction in patients with pituitary tumour who have been treated with transfrontal or transsphenoidal surgery or medication Clin. Endocrinol. (Oxf.) 49 1998 391 396
29. A. Pfefferbaum, E. Adalsteinsson, D. Spielman, E.V. Sullivan, and K.O. Lim In vivo spectroscopic quantification of the N-acetyl moiety, creatine, and choline from large volumes of brain gray and white matter: effects of normal aging Magn. Reson. Med. 41 1999 276 284
30. A. Sartorio, E. Molinari, G. Riva, A. Conti, F. Morabito, and G. Faglia Growth hormone treatment in adults with childhood onset growth hormone deficiency: effects on psychological capabilities Horm. Res. 44 1995 6 11
31. W.E. Sonntag, S.A. Bennett, A.S. Khan, P.L. Thornton, X.W. Xu, R.L. Ingram, and J.K. Brunso-Bechtold Age and insulin-like growth factor-1 modulate N-methyl-d-aspartate receptor subtype expression in rats Brain Res. Bull. 51 2000 331 338
32. P.S. Van Dam, A. Aleman, W.R. de Vries, J.B. Deijen, E.A. Van der Veen, E.H.F. de Haan, and H.P.F. Koppeschaar Growth hormone, insulin-like growth factor-I and cognitive function in adults GH IGF-I Res. 10 2000 S69 S73
33. A.G. Van den Heuvel, J. Van der Grond, L.G. Van Rooij, H.N. Van Wassenaer van Hall, T.U. Hoogenraad, and W.P. Mali Differentiation between portal-systemic encephalopathy and neurodegenerative disorders in patients with Wilson disease: H-1 MR spectroscopy Radiology 203 1997 539 543