Long-term clinical outcome of human immunodeficiency virus-infected patients with discordant immunologic and virologic responses to a protease inhibitor-containing regimen

Journal of Infectious Diseases

Volumn 183, Issue 9, 2001, Pages 1328-1335

  Piketty, Christophe ^a   Weiss, Laurence ^a   Thomas, François ^b   Mohamed, Ali Si ^b   Belec, Laurent ^a   Kazatchkine, Michel D ^a  

^a INSERM   (France)

^b HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INDINAVIR; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; STAVUDINE; VIRUS RNA; ZIDOVUDINE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFICACY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TREATMENT FAILURE;

ADULT; AGED; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HUMANS; INCIDENCE; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MORTALITY; PROSPECTIVE STUDIES; RNA, VIRAL; TIME FACTORS; TREATMENT OUTCOME; VIRAL LOAD;

EID: 0035341522     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/319861     Document Type: Article

References (23)

1. CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART). Swiss HIV Cohort Study
2. Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease
3. Determinants of paradoxical CD4 cell reconstitution after protease inhibitor-containing antiretroviral regimen
4. Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after six months of highly active antiretroviral therapy
5. + T cell response after virologic failure of protease inhibitor-based regimens in patients with human immunodeficiency virus infection
6. Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: A prospective cohort study. Swiss HIV Cohort Study
7. Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2
8. A cellular anti-apoptosis protein is cleaved by the HIV-1 protease
9. HIV-1 protease inhibitor ritonavir modulates susceptibility to apoptosis of uninfected T cells
10. + T cells and decreases their susceptibility to apoptosis in vitro and in vivo
11. T-cell turnover kinetics in patients with a sustained CD4 response after experiencing virologic failure of a protease inhibitor-based regimen
12. Lack of fitness of protease inhibitor-resistant HIV-1 in vivo
13. Viral fitness in patients with discordant CD4 and plasma HIV-RNA evolution following protease inhibitor failure
14. + T cell counts despite virologic failure of protease inhibitor-containing antiretroviral combination therapy
15. HIV-related pulmonary hypertension: Analytic review of 131 cases
16. 3-Year suppression of HIV viremia with indinavir, zidovudine, and lamivudine
17. - T lymphocyte regeneration after anti-retroviral therapy in H1V-1-infected children and adult patients
18. The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection
19. Factors influencing T-cell turnover in HIV-1-seropositive patients
20. Clinical and immunologic response without decrease in virus load in patients with AIDS after 24 months of highly active antiretroviral therapy
21. Incomplete IL-2 response but restoration of T cell reactivity to CMV antigens in patients exhibiting discordant immunological and virological responses under HAART
22. Improvement in CD4 T cell counts in patients with virological treatment failure: Role of changes in spontaneous cell death and thymic output
23. 6 cells/L