Vaccinia virus induces strong immunoregulatory cytokine production in healthy human epidermal keratinocytes: A novel strategy for immune evasion

Journal of Virology

Volumn 79, Issue 12, 2005, Pages 7363-7370

  Liu, Luzheng ^a   Xu, Zhan ^b   Fuhlbrigge, Robert C ^a   Peña Cruz, Victor ^c   Lieberman, Judy ^b   Kupper, Thomas S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b CENTER FOR BLOOD RESEARCH   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 13; TRANSFORMING GROWTH FACTOR BETA;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENDOTHELIUM CELL; EPIDERMIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; IMMUNOSTIMULATION; IMMUNOSURVEILLANCE; KERATINOCYTE; LANGERHANS CELL; NONHUMAN; POXVIRUS; PRIORITY JOURNAL; SKIN FIBROBLAST; SKIN INFECTION; SMALLPOX VIRUS; SYSTEMIC DISEASE; T LYMPHOCYTE; TH2 CELL; VACCINIA VIRUS; VIROGENESIS; VIRUS CELL INTERACTION; VIRUS GENOME; VIRUS REPLICATION;

CYTOKINES; ENDOTHELIUM, VASCULAR; EPIDERMIS; FIBROBLASTS; HUMANS; IMMUNOCOMPETENCE; KERATINOCYTES; MICROCIRCULATION; TH2 CELLS; UP-REGULATION; VACCINIA VIRUS; VIRUS REPLICATION;

POX VIRUS; POXVIRIDAE; VACCINIA; VACCINIA VIRUS; VARIOLA; VARIOLA VIRUS;

EID: 19944412730     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.12.7363-7370.2005     Document Type: Article

References (47)

1. Akdis, C. A., M. Akdis, A. Trautmann, and K. Blaser. 2000. Immune regulation in atopic dermatitis. Curr. Opin. Immunol. 12:641-646.
2. Alcami, A., and G. L. Smith. 1992. A soluble receptor for interleukin-1 beta encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection. Cell 71:153-167.
3. Alcami, A., J. A. Symons, P. D. Collins, T. J. Williams, and G. L. Smith. 1998. Blockade of chemokine activity by a soluble chemokine binding protein from vaccinia virus. J. Immunol. 160:624-633.
4. Alcami, A., J. A. Symons, and G. L. Smith. 2000. The vaccinia virus soluble alpha/beta interferon (IFN) receptor binds to the cell surface and protects cells from the antiviral effects of IFN. J. Virol. 74:11230-11239.
5. Anderson, M. E., and T. J. Siahaan. 2003. Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: designing peptide and small molecule inhibitors. Peptides 24:487-501.
6. Baker, D., D. Butler, B. J. Scallon, J. K. O'Neill, J. L. Turk, and M. Feldmann. 1994. Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins. Eur. J. Immunol. 24:2040-2048.
7. + T cells. J. Immunol. 166:5250-5257.
8. Boyce, S. T., and R. G. Ham. 1983. Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture. J. Investig. Dermatol. 81:33s-40s.
9. Breman, J. G., and D. A. Henderson. 2002. Diagnosis and management of smallpox. N. Engl. J. Med. 346:1300-1308.
10. Caricchio, R., L. McPhie, and P. L. Cohen. 2003. Ultraviolet B radiation-induced cell death: critical role of ultraviolet dose in inflammation and lupus autoantigen redistribution. J. Immunol. 171:5778-5786.
11. Deckers, J. G., S. De Haij, F. J. van der Woude, S. W. van der Kooij, M. R. Daha, and C. van Kooten. 1998. IL-4 and IL-13 augment cytokine- and CD40-induced RANTES production by human renal tubular epithelial cells in vitro. J. Am. Soc. Nephrol. 9:1187-1193.
12. Dunlop, L. R., K. A. Oehlberg, J. J. Reid, D. Avci, and A. M. Rosengard. 2003. Variola virus immune evasion proteins. Microbes Infect. 5:1049-1056.
13. Earl, P. L., N. Cooper, L. S. Wyatt, B. Moss, and M. W. Carroll. 1998. Preparation of cell cultures and vaccinia virus stocks, p. 16.16.4-16.16.6. In K. Struhl (ed.), Current protocols in molecular biology, 2nd ed., vol. 2. John Wiley & Sons, Inc., Mississauga, Ontario, Canada.
14. Engelmayer, J., M. Larsson, M. Suhklewe, A. Chahroudi, W. I. Cox, R. M. Steinman, and N. Bhardwaj. 1999. Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion. J. Immunol. 163:6762-6768.
15. Engler, R. J., J. Kenner, and D. Y. Leung. 2002. Smallpox vaccination: risk considerations for patients with atopic dermatitis. J. Allergy Clin. Immunol. 110:357-365.
16. Fuhlbrigge, R. C., J. D. Kieffer, D. Armerding, and T. S. Kupper. 1997. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature 389:978-981.
17. Haak-Frendscho, M., S. A. Marsters, J. Mordenti, S. Brady, N. A. Gillett, S. A. Chen, and A. Ashkenazi. 1994. Inhibition of TNF by a TNF receptor immunoadhesin. Comparison to an anti-TNF monoclonal antibody. J. Immunol. 152:1347-1353.
18. + regulatory T cell subsets. J. Leukoc. Biol. 74:471-478.
19. Jackson, R. J., A. J. Ramsay, C. D. Christensen, S. Beaton, D. F. Hall, and I. A. Ramshaw. 2001. Expression of mouse interleukin-4 by a recombinant cetromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox. J. Virol. 75:1205-1210.
20. Jacobs, S., E. I. Grussendorf-Conen, I. Rosener, and A. Rubben. 2004. Molecular analysis of the effect of topical imiquimod treatment of HPV 2/27/57-induced common warts. Skin Pharmacol. Physiol. 17:258-266.
21. Knight, P. R., A. Sreekumar, J. Siddiqui, B. Laxman, S. Copeland, A. Chinnaiyan, and D. G. Remick. 2004. Development of a sensitive microarray immunoassay and comparison with standard enzyme-linked immunoassay for cytokine analysis. Shock 21:26-30.
22. Kotwal, G. J., S. N. Isaacs, R. McKenzie, M. M. Frank, and B. Moss. 1990. Inhibition of the complement cascade by the major secretory protein of vaccinia virus. Science 250:827-830.
23. Kupper, T. S., and R. C. Fuhlbrigge. 2004. Immune surveillance in the skin: mechanisms and clinical consequences. Nat. Rev. Immunol. 4:211-222.
24. Lane, J. M. 1969. Vaccination and Henoch-Schoenlein purpura. N. Engl. J. Med. 280:781.
25. Lane, J. M., and J. D. Millar. 1971. Risks of smallpox vaccination complications in the United States. Am. J. Epidemiol. 93:238-240.
26. Letterio, J. J., and A. B. Roberts. 1998. Regulation of immune responses by TGF-beta. Annu. Rev. Immunol. 16:137-161.
27. Li, D., T. G. Turi, A. Schuck, I. M. Freedberg, G. Khitrov, and M. Blumenberg. 2001. Rays and arrays: the transcriptional program in the response of human epidermal keratinocytes to UVB illumination. FASEB J. 15:2533-2535.
28. Lucey, D. R., M. Clerici, and G. M. Shearer. 1996. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin. Microbiol. Rev. 9:532-562.
29. Luethviksson, B. R., and B. Gunnlaugsdottir. 2003. Transforming growth factor-beta as a regulator of site-specific T-cell inflammatory response. Scand. J. Immunol. 58:129-138.
30. Moore, K. W., R. de Waal Malefyt, R. L. Coffman, and A. O'Garra. 2001. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19: 683-765.
31. Moss, B. 2001. Poxviridac: the viruses and their replication, p. 2849-2883. In P. M. Howley et al. (ed.), Fields virology, 4th ed. Lippincott Williams & Wilkins, Philadelphia, Pa.
32. + regulatory T cell activity in both humans and mice. J. Immunol. 172:834-842.
33. Nikkels, A. F., C. Sadzot-Delvaux, and G. E. Pierard. 2004. Absence of intercellular adhesion molecule 1 expression in varicella zoster virus-infected keratinocytes during herpes zoster: another immune evasion strategy? Am. J. Dermatopathol. 26:27-32.
34. Pena-Cruz, V., S. Ito, C. C. Dascher, M. B. Brenner, and M. Sugita. 2003. Epidermal Langerhans cells efficiently mediate CD1a-dependent presentation of microbial lipid antigens to T cells. J. Investig. Dermatol. 121:517-521.
35. Pena-Cruz, V., S. Ito, M. Oukka, K. Yoneda, C. C. Dascher, F. Von Lichtenberg, and M. Sugita. 2001. Extraction of human Langerhans cells: a method for isolation of epidermis-resident dendritic cells. J. Immunol. Methods 255:83-91.
36. Reading, P. C., J. A. Symons, and G. L. Smith. 2003. A soluble chemokine-binding protein from vaccinia virus reduces virus virulence and the inflammatory response to infection. J. Immunol. 170:1435-1442.
37. Robert, C., and T. S. Kupper. 1999. Inflammatory skin diseases, T cells, and immune surveillance. N. Engl. J. Med. 341:1817-1828.
38. Schmelz, M., B. Sodeik, M. Ericsson, E. J. Wolffe, H. Shida, G. Hiller, and G. Griffiths. 1994. Assembly of vaccinia virus: the second wrapping cisterna is derived from the trans Golgi network. J. Virol. 68:130-147.
39. Schon, M., and J. G. Rheinwald. 1996. A limited role for retinoic acid and retinoic acid receptors RAR alpha and RAR beta in regulating keratin 19 expression and keratinization in oral and epidermal keratinocytes. J. Investig. Dermatol. 107:428-438.
40. Seet, B. T., J. B. Johnston, C. R. Brunetti, J. W. Barrett, H. Everett, C. Cameron, J. Sypula, S. H. Nazarian, A. Lucas, and G. McFadden. 2003. Poxviruses and immune evasion. Annu. Rev. Immunol. 21:377-423.
41. Soumelis, V., P. A. Reche, H. Kanzler, W. Yuan, G. Edward, B. Homey, M. Gilliet, S. Ho, S. Antonenko, A. Lauerma, K. Smith, D. German, S. Zurawski, J. Abrams, S. Menon, T. McClanahan, R. de Waal-Malefyt, F. Bazan, R. A. Kastelein, and Y. J. Liu. 2002. Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat. Immunol. 3:673-680.
42. Stillman, B. A., and J. L. Tonkinson. 2000. FAST slides: a novel surface for microarrays. BioTechniques 29:630-635.
43. Wenzel, S. E., J. B. Trudeau, S. Barnes, X. Zhou, M. Cundall, J. Y. Westcott, K. McCord, and H. W. Chu. 2002. TCP-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts. J. Immunol. 169: 4613-4619.
44. Wilson, C. B., and E. K. Marcuse. 2001. Vaccine safety-vaccine benefits: science and the public's perception. Nat. Rev. Immunol. 1:160-165.
45. Wolk, K., S. Kunz, E. Witte, M. Friedrich, K. Asadullah, and R. Sabat. 2004. IL-22 increases the innate immunity of tissues. Immunity 21:241-254.
46. Yamamoto, H., H. Teramoto, K. Uetani, K. Igawa, and E. Shimizu. 2002. Cyclic stretch upregulates interleukin-8 and transforming growth factor-β1 production through a protein kinase C-dependent pathway in alveolar epithelial cells. Respirology 7:103-109.
47. Yuwen, H., J. H. Cox, J. W. Yewdell, J. R. Bennink, and B. Moss. 1993. Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene. Virology 195:732-744.