메뉴 건너뛰기




Volumn 34, Issue 12, 2004, Pages 3582-3594

MHC class I-associated presentation of exogenous peptides is not only enhanced but also prolonged by linking with a C-terminal Lys-Asp-Glu-Leu endoplasmic reticulum retrieval signal

Author keywords

APC; ER retrieval signal; Exogenous peptides; KDEL sequence; MHC class I associated presentation

Indexed keywords

ASPARTIC ACID; BREFELDIN A; GLUTAMIC ACID; LACTACYSTIN; LEUCINE; LYSINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEASOME; SYNTHETIC PEPTIDE; THREONINE; TRYPTOPHAN; TUMOR VACCINE;

EID: 19944395833     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200425215     Document Type: Article
Times cited : (3)

References (41)
  • 2
    • 0033818096 scopus 로고    scopus 로고
    • The dendritic cell and human cancer vaccines
    • Dallal, R. M. and Lotze, M. T., The dendritic cell and human cancer vaccines. Curr. Opin. Immunol. 2000. 12: 583-588.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 583-588
    • Dallal, R.M.1    Lotze, M.T.2
  • 3
    • 0034162484 scopus 로고    scopus 로고
    • The density of peptides displayed by dendritic cells affects immune responses to human tyrosinase and gp100 in HLA-A2 transgenic mice
    • Bullock, T. N., Colella, T. A. and Engelhard, V. H., The density of peptides displayed by dendritic cells affects immune responses to human tyrosinase and gp100 in HLA-A2 transgenic mice. J. Immunol. 2000. 164: 2354-2361.
    • (2000) J. Immunol. , vol.164 , pp. 2354-2361
    • Bullock, T.N.1    Colella, T.A.2    Engelhard, V.H.3
  • 5
    • 0030587077 scopus 로고    scopus 로고
    • Improved induction of melanoma-reactive CTL with peptides; from the melanoma antigen gp100 modified at HLA-A*0201-binding residues
    • Parkhurst, M. R., Salgaller, M. L., Southwood, S., Robbins, P.F, Sette, A., Rosenberg, S. A. and Kawakami, Y., Improved induction of melanoma-reactive CTL with peptides; from the melanoma antigen gp100 modified at HLA-A*0201-binding residues. J. Immunol. 1996. 157: 2539-2548.
    • (1996) J. Immunol. , vol.157 , pp. 2539-2548
    • Parkhurst, M.R.1    Salgaller, M.L.2    Southwood, S.3    Robbins, P.F.4    Sette, A.5    Rosenberg, S.A.6    Kawakami, Y.7
  • 7
    • 0036266363 scopus 로고    scopus 로고
    • Induction of CD4(+) T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells
    • Wang, H. Y., Fu, T., Wang, G., Zeng, G., Perry-Lalley, D. M., Yang, J. C., Restifo, N. P., Hwu, P. and Wang, R. F., Induction of CD4(+) T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells. J. Clin. Invest 2002. 109: 1463-1470.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1463-1470
    • Wang, H.Y.1    Fu, T.2    Wang, G.3    Zeng, G.4    Perry-Lalley, D.M.5    Yang, J.C.6    Restifo, N.P.7    Hwu, P.8    Wang, R.F.9
  • 8
    • 0036168910 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by prolonging antigen presentation on dendritic cells
    • Wang, R. F. and Wang, H. Y., Enhancement of antitumor immunity by prolonging antigen presentation on dendritic cells. Nat. Biotechnol. 2002. 20: 149-154.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 149-154
    • Wang, R.F.1    Wang, H.Y.2
  • 9
    • 0035117550 scopus 로고    scopus 로고
    • Immunization with tumor-associated epitopes fused to an endoplasmic reticulum translocation signal sequence affords protection against tumors with down-regulated expression of MHC and peptide transporters
    • Sherritt, M., Cooper, L., Moss, D. J., Kienzle, N., Altman, J. and Khanna, R., Immunization with tumor-associated epitopes fused to an endoplasmic reticulum translocation signal sequence affords protection against tumors with down-regulated expression of MHC and peptide transporters. Int. Immunol. 2001. 13: 265-271.
    • (2001) Int. Immunol. , vol.13 , pp. 265-271
    • Sherritt, M.1    Cooper, L.2    Moss, D.J.3    Kienzle, N.4    Altman, J.5    Khanna, R.6
  • 10
    • 0033842255 scopus 로고    scopus 로고
    • Synthetic insertion signal sequences enhance MHC class I presentation of a peptide from the melanoma antigen MART-1
    • Minev, B. R., Chavez, F. L., Dudouet, B. M. and Mitchell, M. S., Synthetic insertion signal sequences enhance MHC class I presentation of a peptide from the melanoma antigen MART-1. Eur J. Immunol. 2000. 30: 2115-2124.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2115-2124
    • Minev, B.R.1    Chavez, F.L.2    Dudouet, B.M.3    Mitchell, M.S.4
  • 11
    • 2642607007 scopus 로고    scopus 로고
    • An endoplasmic reticulum-targeting signal sequence enhances the immunogenicity of an immunorecessive simian virus 40 large T antigen cytotoxic T-lymphocyte epitope
    • Fu, T. M., Mylin, L. M., Schell, T. D., Bacik, I., Russ, G., Yewdell, J. W., Bennink, J. R. and Tevethia, S. S., An endoplasmic reticulum-targeting signal sequence enhances the immunogenicity of an immunorecessive simian virus 40 large T antigen cytotoxic T-lymphocyte epitope. J. Virol. 1998. 72: 1469-1481.
    • (1998) J. Virol. , vol.72 , pp. 1469-1481
    • Fu, T.M.1    Mylin, L.M.2    Schell, T.D.3    Bacik, I.4    Russ, G.5    Yewdell, J.W.6    Bennink, J.R.7    Tevethia, S.S.8
  • 13
    • 0035325257 scopus 로고    scopus 로고
    • Peptide-based targeting of fluorophores to organelles in living cells
    • Pap, E. H., Dansen, T. B., van Summeren, R. and Wirtz, K. W., Peptide-based targeting of fluorophores to organelles in living cells. Exp. Cell Res. 2001. 265: 288-293.
    • (2001) Exp. Cell Res. , vol.265 , pp. 288-293
    • Pap, E.H.1    Dansen, T.B.2    van Summeren, R.3    Wirtz, K.W.4
  • 15
    • 0029966286 scopus 로고    scopus 로고
    • The requirement for proteasome activity class I major histocompatibility complex antigen presentation is dictated by the length of preprocessed antigen
    • Yang, B., Hahn, Y. S., Hahn, C. S. and Braciale, T. J., The requirement for proteasome activity class I major histocompatibility complex antigen presentation is dictated by the length of preprocessed antigen. J. Exp. Med. 1996. 183: 1545-1552.
    • (1996) J. Exp. Med. , vol.183 , pp. 1545-1552
    • Yang, B.1    Hahn, Y.S.2    Hahn, C.S.3    Braciale, T.J.4
  • 16
    • 0029920909 scopus 로고    scopus 로고
    • The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4
    • Levitsky, V., Zhang, Q. J., Levitskaya, J. and Masucci, M. G., The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4. J. Exp. Med. 1996. 183: 915-926.
    • (1996) J. Exp. Med. , vol.183 , pp. 915-926
    • Levitsky, V.1    Zhang, Q.J.2    Levitskaya, J.3    Masucci, M.G.4
  • 17
    • 0030876616 scopus 로고    scopus 로고
    • Retrograde transport of KDEL-bearing B-fragment of Shiga toxin
    • Johannes, L., Tenza, D., Antony, C. and Goud, B., Retrograde transport of KDEL-bearing B-fragment of Shiga toxin. J. Biol. Chem. 1997. 272: 19554-19561.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19554-19561
    • Johannes, L.1    Tenza, D.2    Antony, C.3    Goud, B.4
  • 18
    • 0028091981 scopus 로고
    • Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells
    • Griffiths, G., Ericsson, M., Krijnse-Locker, J., Nilsson, T., Goud, B., Soling, H. D., Tang, B. L., Wong, S. H. and Hong, W., Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells. J. Cell Biol. 1994. 127: 1557-1574.
    • (1994) J. Cell Biol. , vol.127 , pp. 1557-1574
    • Griffiths, G.1    Ericsson, M.2    Krijnse-Locker, J.3    Nilsson, T.4    Goud, B.5    Soling, H.D.6    Tang, B.L.7    Wong, S.H.8    Hong, W.9
  • 19
    • 0032969203 scopus 로고    scopus 로고
    • The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin-1, during retrograde transport from the Golgi complex to the endoplasmic reticulum
    • Jackson, M. E., Simpson, J. C., Girod, A., Pepperkok, R., Roberts, L. M. and Lord, J. M., The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin-1, during retrograde transport from the Golgi complex to the endoplasmic reticulum. J. Cell Sci. 1999. 112: 467-475.
    • (1999) J. Cell Sci. , vol.112 , pp. 467-475
    • Jackson, M.E.1    Simpson, J.C.2    Girod, A.3    Pepperkok, R.4    Roberts, L.M.5    Lord, J.M.6
  • 20
    • 0032476577 scopus 로고    scopus 로고
    • KDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p
    • Majoul, I., Sohn, K., Wieland, F. T., Pepperkok, R., Pizza, M., Hillemann, J. and Soling, H. D., KDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p. J. Cell Biol. 1998. 143: 601-612.
    • (1998) J. Cell Biol. , vol.143 , pp. 601-612
    • Majoul, I.1    Sohn, K.2    Wieland, F.T.3    Pepperkok, R.4    Pizza, M.5    Hillemann, J.6    Soling, H.D.7
  • 21
    • 0032538927 scopus 로고    scopus 로고
    • Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transport
    • Mallard, F., Antony, C., Tenza, D., Salamero, J., Goud, B. and Johannes, L., Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transport. J. Cell Biol. 1998. 143: 973-990.
    • (1998) J. Cell Biol. , vol.143 , pp. 973-990
    • Mallard, F.1    Antony, C.2    Tenza, D.3    Salamero, J.4    Goud, B.5    Johannes, L.6
  • 22
    • 0026684124 scopus 로고
    • Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
    • Sandvig, K., Garred, O., Prydz, K., Kozlov, J. V., Hansen, S. H. and van Deurs, B., Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum. Nature 1992. 358: 510-512.
    • (1992) Nature , vol.358 , pp. 510-512
    • Sandvig, K.1    Garred, O.2    Prydz, K.3    Kozlov, J.V.4    Hansen, S.H.5    van Deurs, B.6
  • 23
    • 0029149603 scopus 로고
    • Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis
    • Reis e Sousa, C. and Germain, R. N., Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J. Exp. Med. 1995. 182: 841-851.
    • (1995) J. Exp. Med. , vol.182 , pp. 841-851
    • Reis e Sousa, C.1    Germain, R.N.2
  • 24
    • 0028910938 scopus 로고
    • A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules
    • Kovacsovics-Bankowski, M. and Rock, K. L., A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science 1995. 267: 243-246.
    • (1995) Science , vol.267 , pp. 243-246
    • Kovacsovics-Bankowski, M.1    Rock, K.L.2
  • 25
    • 0027292868 scopus 로고
    • Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages
    • Kovacsovics-Bankowski, M., Clark, K., Benacerraf, B. and Rock, K. L., Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc. Natl. Aced. Sci. USA 1993. 90: 4942-4946.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4942-4946
    • Kovacsovics-Bankowski, M.1    Clark, K.2    Benacerraf, B.3    Rock, K.L.4
  • 28
    • 0028850506 scopus 로고
    • Processing of exogenous heat-aggregated (denatured) and particulate (native) hepatitis B surface antigen for class I-restricted epitope presentation
    • Schirmbeck, R., Bohm, W., Melber, K. and Reimann, J., Processing of exogenous heat-aggregated (denatured) and particulate (native) hepatitis B surface antigen for class I-restricted epitope presentation. J. Immunol. 1995. 155: 4676-4684.
    • (1995) J. Immunol. , vol.155 , pp. 4676-4684
    • Schirmbeck, R.1    Bohm, W.2    Melber, K.3    Reimann, J.4
  • 29
    • 0033561792 scopus 로고    scopus 로고
    • Covalent linkage to beta2-microglobulin enhances the MHC stability and antigenicity of suboptimal CTL epitopes
    • Uger, R. A., Chan, S. M. and Barber, B. H., Covalent linkage to beta2-microglobulin enhances the MHC stability and antigenicity of suboptimal CTL epitopes. J. Immunol. 1999. 162: 6024-6028.
    • (1999) J. Immunol. , vol.162 , pp. 6024-6028
    • Uger, R.A.1    Chan, S.M.2    Barber, B.H.3
  • 30
    • 0030873428 scopus 로고    scopus 로고
    • Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells
    • Day, P. M., Yewdell, J. W., Porgador, A., Germain, R. N. and Bennink, J. R., Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells. Proc. Natl. Acad. Sci. USA 1997. 94: 8064-8069.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8064-8069
    • Day, P.M.1    Yewdell, J.W.2    Porgador, A.3    Germain, R.N.4    Bennink, J.R.5
  • 31
    • 0035451352 scopus 로고    scopus 로고
    • Exogenous peptides presented by transporter associated with antigen processing (TAP)-deficient and TAP-competent cells: Intracellular loading and kinetics of presentation
    • Luft, T., Rizkalla, M., Tai, T. Y., Chen, Q., MacFarlan, R. I., Davis, I. D., Maraskovsky, E. and Cebon, J., Exogenous peptides presented by transporter associated with antigen processing (TAP)-deficient and TAP-competent cells: intracellular loading and kinetics of presentation. J. Immunol. 2001. 167: 2529-2537.
    • (2001) J. Immunol. , vol.167 , pp. 2529-2537
    • Luft, T.1    Rizkalla, M.2    Tai, T.Y.3    Chen, Q.4    MacFarlan, R.I.5    Davis, I.D.6    Maraskovsky, E.7    Cebon, J.8
  • 32
    • 0035062088 scopus 로고    scopus 로고
    • Exogenous peptides enter the endoplasmic reticulum of TAP-deficient cells and induce the maturation of nascent MHC class I molecules
    • Levitt, J. M., Howell, D. D., Rodgers, J. R. and Rich, R. R., Exogenous peptides enter the endoplasmic reticulum of TAP-deficient cells and induce the maturation of nascent MHC class I molecules. Eur. J. Immunol. 2001. 31: 1181-1190.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1181-1190
    • Levitt, J.M.1    Howell, D.D.2    Rodgers, J.R.3    Rich, R.R.4
  • 33
    • 0024324442 scopus 로고
    • Association of class I major histocompatibility heavy and light chains induced by viral peptides
    • Townsend, A., Ohlen, C., Bastin, J., Ljunggren, H. G., Foster, L. and Karre, K., Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature 1989. 340: 443-448.
    • (1989) Nature , vol.340 , pp. 443-448
    • Townsend, A.1    Ohlen, C.2    Bastin, J.3    Ljunggren, H.G.4    Foster, L.5    Karre, K.6
  • 35
    • 0036777957 scopus 로고    scopus 로고
    • The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides
    • Goldberg, A. L., Cascio, P., Saric, T. and Rock, K. L., The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides. Mol. Immunol. 2002. 39: 147-164.
    • (2002) Mol. Immunol. , vol.39 , pp. 147-164
    • Goldberg, A.L.1    Cascio, P.2    Saric, T.3    Rock, K.L.4
  • 36
    • 0028096715 scopus 로고
    • Trimming of antigenic peptides in an early secretory compartment
    • Snyder, H. L., Yewdell, J. W. and Bennink, J. R., Trimming of antigenic peptides in an early secretory compartment. J. Exp. Med. 1994. 180: 2389-2394.
    • (1994) J. Exp. Med. , vol.180 , pp. 2389-2394
    • Snyder, H.L.1    Yewdell, J.W.2    Bennink, J.R.3
  • 37
    • 0034913229 scopus 로고    scopus 로고
    • ER aminopeptidases generate a unique pool of peptides for MHC class I molecules
    • Serwold, T., Gaw, S. and Shastri, N., ER aminopeptidases generate a unique pool of peptides for MHC class I molecules. Nat. Immunol. 2001. 2: 644-651.
    • (2001) Nat. Immunol. , vol.2 , pp. 644-651
    • Serwold, T.1    Gaw, S.2    Shastri, N.3
  • 38
    • 0028925556 scopus 로고
    • Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum
    • Elliott, T., Willis, A., Cerundolo, V. and Townsend, A., Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum. J. Exp. Med. 1995. 181: 1481-1491.
    • (1995) J. Exp. Med. , vol.181 , pp. 1481-1491
    • Elliott, T.1    Willis, A.2    Cerundolo, V.3    Townsend, A.4
  • 39
    • 0033574441 scopus 로고    scopus 로고
    • Posttranslational removal of the carboxyl-terminal KDEL of the cysteine protease SH-EP occurs prior to maturation of the enzyme
    • Okamoto, T., Minamikawa, T., Edward, G., Vakharia, V., Herman, E. and Okomoto, T., Posttranslational removal of the carboxyl-terminal KDEL of the cysteine protease SH-EP occurs prior to maturation of the enzyme. J. Biol. Chem. 1999. 274: 11390-11398.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11390-11398
    • Okamoto, T.1    Minamikawa, T.2    Edward, G.3    Vakharia, V.4    Herman, E.5    Okomoto, T.6
  • 40
    • 0024583817 scopus 로고
    • Induction of ovalbumin-specific cytotoxic T cells by in vivo peptide immunization
    • Carbone, F. R. and Bevan, M. J., Induction of ovalbumin-specific cytotoxic T cells by in vivo peptide immunization. J. Exp. Med. 1989. 169: 603-612.
    • (1989) J. Exp. Med. , vol.169 , pp. 603-612
    • Carbone, F.R.1    Bevan, M.J.2
  • 41
    • 0000810758 scopus 로고
    • Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice
    • Steinman, R. M. and Witmer, M. D., Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice. Proc. Natl. Acad. Sci. USA 1978. 75: 5132-5136.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 5132-5136
    • Steinman, R.M.1    Witmer, M.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.