Total asymmetric synthesis of (-)-conduramine B-1 and of its enantiomer. N-Benzyl derivatives of conduramine B-1 are β-glucosidase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 12, 2005, Pages 3071-3075

  Łysek, Robert ^a   Schütz, Catherine ^a   Vogel, Pierre ^a  

^a EPFL   (Switzerland)

Author keywords

Glucosidases; Asymmetric synthesis; Conduramine B 1; Inhibition; Naked sugars

Indexed keywords

ALDEHYDE DERIVATIVE; ALPHA GLUCOSIDASE; BENZYL DERIVATIVE; BETA GLUCOSIDASE; BETA GLUCOSIDASE INHIBITOR; CONDURAMINE B 1; ENZYME INHIBITOR; GLUCAN 1,4 ALPHA GLUCOSIDASE; N (4 PHENYLBENZYL)CONDURAMINE B 1; UNCLASSIFIED DRUG; XYLAN 1,4 BETA XYLOSIDASE;

ARTICLE; BENZYLATION; CONTROLLED STUDY; DRUG SYNTHESIS; ENANTIOMER; ENZYME INHIBITION; NONHUMAN;

ALPHA-GLUCOSIDASES; ASPERGILLUS NIGER; BACTERIA, ANAEROBIC; BICYCLO COMPOUNDS; CELLULASES; CYCLOHEXENES; ENZYME INHIBITORS; HEXOSAMINES; MOLECULAR STRUCTURE; PRUNUS; SACCHAROMYCES CEREVISIAE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; XYLOSIDASES;

EID: 19844364740     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.04.023     Document Type: Article

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