Pharmacokinetic variability of routinely administered bisoprolol in middle-aged and elderly Japanese patients

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 5, 2005, Pages 876-881

  Taguchi, Masato ^a   Nozawa, Takashi ^b   Igawa, Akihiko ^b   Inoue, Hiroshi ^b   Takesono, Chihiro ^a   Tahara, Katsutoshi ^a   Hashimoto, Yukiya ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Bisoprolol; Elderly patient; Japanese; Nonlinear mixed effects model (NONMEM); Pharmacokinetics

Indexed keywords

BISOPROLOL; BISOPROLOL FUMARATE; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6;

ADULT; AGED; ARTICLE; BODY WEIGHT; CLINICAL ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE REGIMEN; FEMALE; GENOTYPE; HUMAN; JAPAN; KIDNEY FUNCTION; MALE; SEX DIFFERENCE; STEADY STATE;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ASIAN CONTINENTAL ANCESTRY GROUP; BISOPROLOL; FEMALE; HUMANS; MALE; MIDDLE AGED; VARIATION (GENETICS);

EID: 19644381104     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.28.876     Document Type: Article

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