메뉴 건너뛰기




Volumn 65, Issue 11, 2005, Pages 4587-4597

LMO3 interacts with neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; LIM PROTEIN; PROTEIN LMO3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HEN2; UNCLASSIFIED DRUG;

EID: 19644363959     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-4630     Document Type: Article
Times cited : (99)

References (42)
  • 1
    • 0031966041 scopus 로고    scopus 로고
    • LIM domains: Multiple roles as adaptors and functional modifiers in protein interactions
    • Dawid IB, Breen JJ, Toyama R. LIM domains: multiple roles as adaptors and functional modifiers in protein interactions. Trends Genet 1998;14:156-62.
    • (1998) Trends Genet , vol.14 , pp. 156-162
    • Dawid, I.B.1    Breen, J.J.2    Toyama, R.3
  • 2
    • 0028060189 scopus 로고
    • The LIM domain: A new structural motif found in zinc-finger-like proteins
    • Sanchez-Garcia I, Rabbitts TH. The LIM domain: a new structural motif found in zinc-finger-like proteins. Trends Genet 1994;10:315-20.
    • (1994) Trends Genet , vol.10 , pp. 315-320
    • Sanchez-Garcia, I.1    Rabbitts, T.H.2
  • 4
    • 0032168564 scopus 로고    scopus 로고
    • LMO T-cell translocation oncogenes typify genes activated by chromosomal translocations that alter transcription and developmental processes
    • Rabbitts TH. LMO T-cell translocation oncogenes typify genes activated by chromosomal translocations that alter transcription and developmental processes. Genes Dev 1998;12:2651-7.
    • (1998) Genes Dev , vol.12 , pp. 2651-2657
    • Rabbitts, T.H.1
  • 5
    • 0026728357 scopus 로고
    • Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma
    • McGuire EA, Rintoul CE, Sclar GM, Korsmeyer SJ. Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma. Mol Cell Biol 1992;12:4186-96.
    • (1992) Mol Cell Biol , vol.12 , pp. 4186-4196
    • McGuire, E.A.1    Rintoul, C.E.2    Sclar, G.M.3    Korsmeyer, S.J.4
  • 6
    • 0026446264 scopus 로고
    • T-cell acute lymphoblastic lymphoma induced in transgenic mice by the RBTN1 and RBTN2 LIM-domain genes
    • Fisch P, Boehm T, Lavenir I, et al. T-cell acute lymphoblastic lymphoma induced in transgenic mice by the RBTN1 and RBTN2 LIM-domain genes. Oncogene 1992;7:2389-97.
    • (1992) Oncogene , vol.7 , pp. 2389-2397
    • Fisch, P.1    Boehm, T.2    Lavenir, I.3
  • 7
    • 0030843262 scopus 로고    scopus 로고
    • Disruption of T-cell differentiation precedes T-cell tumor formation in LMO-2 (rhombotin-2) transgenic mice
    • Neale GA, Rehg JE, Goorha RM. Disruption of T-cell differentiation precedes T-cell tumor formation in LMO-2 (rhombotin-2) transgenic mice. Leukemia 1997;3:289-90.
    • (1997) Leukemia , vol.3 , pp. 289-290
    • Neale, G.A.1    Rehg, J.E.2    Goorha, R.M.3
  • 8
    • 0032530133 scopus 로고    scopus 로고
    • Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis
    • Kenny DA, Jurata LW, Saga Y, Gill GN. Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis. Proc Natl Acad Sci U S A 1998;95:11257-62.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 11257-11262
    • Kenny, D.A.1    Jurata, L.W.2    Saga, Y.3    Gill, G.N.4
  • 9
    • 0035807896 scopus 로고    scopus 로고
    • The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer
    • Visvader JE, Venter D, Hahm K, et al. The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer. Proc Natl Acad Sci U S A 2001;98:14452-7.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14452-14457
    • Visvader, J.E.1    Venter, D.2    Hahm, K.3
  • 10
    • 0037040874 scopus 로고    scopus 로고
    • The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity
    • Sum EY, Peng B, Yu X, et al. The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity. J Biol Chem 2002;277:7849-56.
    • (2002) J Biol Chem , vol.277 , pp. 7849-7856
    • Sum, E.Y.1    Peng, B.2    Yu, X.3
  • 11
    • 0026641619 scopus 로고
    • The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development
    • Foroni L, Boehm T, White L, et al. The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development. J Mol Biol 1992;226:747-61.
    • (1992) J Mol Biol , vol.226 , pp. 747-761
    • Foroni, L.1    Boehm, T.2    White, L.3
  • 12
    • 0027973545 scopus 로고
    • Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia
    • Wadman I, Li J, Bash RO, et al. Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia EMBO J 1994;13:4831-9.
    • (1994) EMBO J , vol.13 , pp. 4831-4839
    • Wadman, I.1    Li, J.2    Bash, R.O.3
  • 13
    • 0029981648 scopus 로고    scopus 로고
    • Protein dimerization between Lmo2 (Rbtn2) and Tall alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice
    • Larson RC, Lavenir I, Larson TA, et al. Protein dimerization between Lmo2 (Rbtn2) and Tall alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice. EMBO J 1996;15:1021-7.
    • (1996) EMBO J , vol.15 , pp. 1021-1027
    • Larson, R.C.1    Lavenir, I.2    Larson, T.A.3
  • 14
    • 0026687342 scopus 로고
    • HEN1 and HEN2: A subgroup of basic helix-loop-helix genes that are coexpressed in a human neuroblastoma
    • Brown L, Espinosa R III, Le Beau MM, Siciliano MJ, Baer R. HEN1 and HEN2: a subgroup of basic helix-loop-helix genes that are coexpressed in a human neuroblastoma. Proc Natl Acad Sci U S A 1992;89:8492-6.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 8492-8496
    • Brown, L.1    Espinosa III, R.2    Le Beau, M.M.3    Siciliano, M.J.4    Baer, R.5
  • 15
    • 0026516559 scopus 로고
    • Molecular characterization of NSCL, a gene encoding a helix-loop-helix protein expressed in the developing nervous system
    • Begley CG, Lipkowitz S, Gobel V. et al. Molecular characterization of NSCL, a gene encoding a helix-loop-helix protein expressed in the developing nervous system. Proc Natl Acad Sci U S A 1992;89:38-42.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 38-42
    • Begley, C.G.1    Lipkowitz, S.2    Gobel, V.3
  • 16
    • 0026726144 scopus 로고
    • Effect of genetic factors on prognosis and treatment
    • Brodeur GM, Azar C, Brother M, et al. Effect of genetic factors on prognosis and treatment. Cancer 1992;70:1685-94.
    • (1992) Cancer , vol.70 , pp. 1685-1694
    • Brodeur, G.M.1    Azar, C.2    Brother, M.3
  • 17
    • 0026607625 scopus 로고
    • Molecular basis of clinical heterogeneity in neuroblastoma
    • Brodeur GM, Nakagawara A. Molecular basis of clinical heterogeneity in neuroblastoma. J Pediatr Hematol Oncol 1992;14:111-6.
    • (1992) J Pediatr Hematol Oncol , vol.14 , pp. 111-116
    • Brodeur, G.M.1    Nakagawara, A.2
  • 18
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 1984;224:1121-4.
    • (1984) Science , vol.224 , pp. 1121-1124
    • Brodeur, G.M.1    Seeger, R.C.2    Schwab, M.3    Varmus, H.E.4    Bishop, J.M.5
  • 19
    • 0022388606 scopus 로고
    • Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
    • Seeger RC, Brodeur GM, Sather H, et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985;313:1111-6.
    • (1985) N Engl J Med , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3
  • 20
    • 0026552457 scopus 로고
    • Inverse relationship between trk expression and N-myc amplification in human neuroblastomas
    • Nakagawara A, Arima M, Azar CG, Scavarda NJ, Brodeur GM. Inverse relationship between trk expression and N-myc amplification in human neuroblastomas. Cancer Res 1992;52:1364-8.
    • (1992) Cancer Res , vol.52 , pp. 1364-1368
    • Nakagawara, A.1    Arima, M.2    Azar, C.G.3    Scavarda, N.J.4    Brodeur, G.M.5
  • 22
    • 0027933192 scopus 로고
    • CD44H expression by human neuroblastoma cells: Relation to MYCN amplification and lineage differentiation
    • Gross N, Beretta C, Peruisseau G, Jackson D, Simmons D, Beck D. CD44H expression by human neuroblastoma cells: relation to MYCN amplification and lineage differentiation. Cancer Res 1994;54:4238-42.
    • (1994) Cancer Res , vol.54 , pp. 4238-4242
    • Gross, N.1    Beretta, C.2    Peruisseau, G.3    Jackson, D.4    Simmons, D.5    Beck, D.6
  • 23
    • 19044380776 scopus 로고    scopus 로고
    • Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma
    • Berwanger B, Hartmann O, Bergmann E, et al. Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma. Cancer Cell 2002;2:377-86.
    • (2002) Cancer Cell , vol.2 , pp. 377-386
    • Berwanger, B.1    Hartmann, O.2    Bergmann, E.3
  • 24
    • 0042836576 scopus 로고    scopus 로고
    • Expression profiling and characterization of 4200 genes cloned from primary neuroblastomas: Identification of 305 genes differentially expressed between favorable and unfavorable subsets
    • Ohira M, Morohashi A, Inuzuka H. et al. Expression profiling and characterization of 4200 genes cloned from primary neuroblastomas: identification of 305 genes differentially expressed between favorable and unfavorable subsets. Oncogene 2003;22:5525-36.
    • (2003) Oncogene , vol.22 , pp. 5525-5536
    • Ohira, M.1    Morohashi, A.2    Inuzuka, H.3
  • 25
    • 0033653613 scopus 로고    scopus 로고
    • Hunting the subset-specific genes of neuroblastoma: Expression profiling and differential screening of the full-length-enriched oligo-capping cDNA libraries
    • Ohira M, Shishikura T, Kawamoto T, et al. Hunting the subset-specific genes of neuroblastoma: expression profiling and differential screening of the full-length-enriched oligo-capping cDNA libraries. Med Pediatr Oncol 2000;35:547-9.
    • (2000) Med Pediatr Oncol , vol.35 , pp. 547-549
    • Ohira, M.1    Shishikura, T.2    Kawamoto, T.3
  • 26
    • 0027239723 scopus 로고
    • Revisions of the international criteria for neurobiastoma diagnosis, staging, and response to treatment
    • Brodeur GM, Pritchard J. Berthold F, et al. Revisions of the international criteria for neurobiastoma diagnosis, staging, and response to treatment. J Clin Oncol 1993;11:1466-77.
    • (1993) J Clin Oncol , vol.11 , pp. 1466-1477
    • Brodeur, G.M.1    Pritchard, J.2    Berthold, F.3
  • 27
    • 19644395018 scopus 로고    scopus 로고
    • Prospective study for establishing the optimal therapy of infantile neuroblastoma in Japan
    • Matsumura T, Iehara T, Sawada T, Tsuchida Y. Prospective study for establishing the optimal therapy of infantile neuroblastoma in Japan. Med Pediatr Oncol 1998;31:210.
    • (1998) Med Pediatr Oncol , vol.31 , pp. 210
    • Matsumura, T.1    Iehara, T.2    Sawada, T.3    Tsuchida, Y.4
  • 28
    • 17344394998 scopus 로고    scopus 로고
    • Study Group of Japan for Treatment of Advanced Neuroblastoma, Tokyo, Japan. Stratification of treatment of stage 4 neuroblastoma patients based on N-myc amplification status
    • Kaneko M, Nishihira H, Mugishima H, et al.; Study Group of Japan for Treatment of Advanced Neuroblastoma, Tokyo, Japan. Stratification of treatment of stage 4 neuroblastoma patients based on N-myc amplification status. Med Pediatr Oncol 1998;31:1-7.
    • (1998) Med Pediatr Oncol , vol.31 , pp. 1-7
    • Kaneko, M.1    Nishihira, H.2    Mugishima, H.3
  • 29
    • 0030729636 scopus 로고    scopus 로고
    • Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects
    • Takihara Y, Tomotsune D, Shirai M, et al. Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects. Development 1997;124:3673-82.
    • (1997) Development , vol.124 , pp. 3673-3682
    • Takihara, Y.1    Tomotsune, D.2    Shirai, M.3
  • 30
    • 0029906061 scopus 로고    scopus 로고
    • Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins
    • Agulnick AD, Taira M, Breen JJ, Tanaka T, Dawid IB, Westphal H. Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins. Nature 1996;384:270-2.
    • (1996) Nature , vol.384 , pp. 270-272
    • Agulnick, A.D.1    Taira, M.2    Breen, J.J.3    Tanaka, T.4    Dawid, I.B.5    Westphal, H.6
  • 31
    • 0029909107 scopus 로고    scopus 로고
    • Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
    • Jurata LW, Kenny DA, Gill GN. Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development Proc Natl Acad Sci U S A 1996;93:11693-8.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11693-11698
    • Jurata, L.W.1    Kenny, D.A.2    Gill, G.N.3
  • 32
    • 0030923755 scopus 로고    scopus 로고
    • A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
    • Bach I, Carriere C, Ostendorff HP, Andersen B, Rosenfeld MG. A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins. Genes Dev 1997;11:1370-80.
    • (1997) Genes Dev , vol.11 , pp. 1370-1380
    • Bach, I.1    Carriere, C.2    Ostendorff, H.P.3    Andersen, B.4    Rosenfeld, M.G.5
  • 33
    • 0028799441 scopus 로고
    • Association of erythroid transcription factors: Complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1
    • Osada H, Grutz G, Axelson H, Forster A, Rabbitts TH. Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1. Proc Natl Acad Sci U S A 1995;92:9585-9.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9585-9589
    • Osada, H.1    Grutz, G.2    Axelson, H.3    Forster, A.4    Rabbitts, T.H.5
  • 34
    • 0027980311 scopus 로고
    • The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells
    • Valge-Archer VE, Osada H, Warren AJ, et al. The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells. Proc Natl Acad Sci U S A 1994;91:8617-21.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 8617-8621
    • Valge-Archer, V.E.1    Osada, H.2    Warren, A.J.3
  • 35
    • 0033970466 scopus 로고    scopus 로고
    • Regulation of neurogenesis by interactions between HEN1 and neuronal LMO proteins
    • Bao J, Talmage DA, Role LW, Gautier J. Regulation of neurogenesis by interactions between HEN1 and neuronal LMO proteins. Development 2000;127:425-35.
    • (2000) Development , vol.127 , pp. 425-435
    • Bao, J.1    Talmage, D.A.2    Role, L.W.3    Gautier, J.4
  • 36
    • 0031051552 scopus 로고    scopus 로고
    • Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL
    • Ono Y, Fukuhara N, Yoshie O. Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL. J Biol Chem 1997;272:4576-81.
    • (1997) J Biol Chem , vol.272 , pp. 4576-4581
    • Ono, Y.1    Fukuhara, N.2    Yoshie, O.3
  • 37
    • 0030921503 scopus 로고    scopus 로고
    • An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with to generate T-cell malignancies in transgenic mice
    • Aplan PD, Jones CA, Chervinsky DS, et al. An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with to generate T-cell malignancies in transgenic mice. EMBO J 1997;16:2408-19.
    • (1997) EMBO J , vol.16 , pp. 2408-2419
    • Aplan, P.D.1    Jones, C.A.2    Chervinsky, D.S.3
  • 38
    • 0037086267 scopus 로고    scopus 로고
    • Expression of the neurotrophin receptor TrkA down-regulates expression and function of angiogenic stimulators in SH-SY5Y neuroblastoma cells
    • Eggert A, Grotzer MA, Ikegaki N, Liu XG, Evans AE, Brodeur GM. Expression of the neurotrophin receptor TrkA down-regulates expression and function of angiogenic stimulators in SH-SY5Y neuroblastoma cells. Cancer Res 2002;62:1802-8.
    • (2002) Cancer Res , vol.62 , pp. 1802-1808
    • Eggert, A.1    Grotzer, M.A.2    Ikegaki, N.3    Liu, X.G.4    Evans, A.E.5    Brodeur, G.M.6
  • 39
    • 0031724589 scopus 로고    scopus 로고
    • TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3
    • Ono Y, Fukuhara N, Yoshie O. TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3. Mol Cell Biol 1998;18:6939-50.
    • (1998) Mol Cell Biol , vol.18 , pp. 6939-6950
    • Ono, Y.1    Fukuhara, N.2    Yoshie, O.3
  • 40
    • 0029743372 scopus 로고    scopus 로고
    • Conditional expression of N-myc in human neuroblastoma cells increases expression of α-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
    • Lutz W, Stohr M, Schurmann J, Wenzel A, Lohr A, Schwab M. Conditional expression of N-myc in human neuroblastoma cells increases expression of α-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 1996;13:803-12.
    • (1996) Oncogene , vol.13 , pp. 803-812
    • Lutz, W.1    Stohr, M.2    Schurmann, J.3    Wenzel, A.4    Lohr, A.5    Schwab, M.6
  • 41
    • 0035899344 scopus 로고    scopus 로고
    • A DNA microarray screen for genes involved in c-MYC and N-MYC oncogenesis in human tumors
    • Schuldiner O, Benvenisty N. A DNA microarray screen for genes involved in c-MYC and N-MYC oncogenesis in human tumors. Oncogene 2001;20:4984-94.
    • (2001) Oncogene , vol.20 , pp. 4984-4994
    • Schuldiner, O.1    Benvenisty, N.2
  • 42
    • 0036168999 scopus 로고    scopus 로고
    • Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma
    • Shohet JM, Hicks MJ, Pion SE, et al. Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma. Cancer Res 2002;62:1123-8.
    • (2002) Cancer Res , vol.62 , pp. 1123-1128
    • Shohet, J.M.1    Hicks, M.J.2    Pion, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.