Transdifferentiation-dependent expression of α-SMA in hepatic stellate cells does not involve TGF-β pathways leading to coinduction of collagen type I and thrombospondin-2

Matrix Biology

Volumn 24, Issue 3, 2005, Pages 198-207

  Lindert, Susanne ^a   Wickert, Lucia ^a   Sawitza, Iris ^a   Wiercinska, Eliza ^b   Gressner, Axel M ^a   Dooley, Steven ^b   Breitkopf, Katja ^b  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Dexamethasone; Fibrosis; Liver; p38; Smads

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; DEXAMETHASONE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; SYNAPTOPHYSIN; THROMBOSPONDIN 2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; FIBROGENESIS; LIVER CELL; MALE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STELLATE CELL;

ACTINS; ANIMALS; CELL DIFFERENTIATION; COLLAGEN TYPE I; DEXAMETHASONE; DNA-BINDING PROTEINS; EXTRACELLULAR MATRIX; FIBROBLASTS; GLUCOCORTICOIDS; HUMANS; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SMAD2 PROTEIN; THROMBOSPONDINS; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMALIA;

EID: 19544394700     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matbio.2005.03.003     Document Type: Article

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