Regulatory sequence responsible for insulin destabilization of cytochrome P450 2B1 (CYP2B1) mRNA

Biochemical Journal

Volumn 388, Issue 1, 2005, Pages 227-235

  Truong, Nhu Traï ^a   Moncion, Arlette ^a   Barouki, Robert ^a   Beaune, Philippe ^a   De Waziers, Isabelle ^a  

^a INSERM   (France)

Author keywords

Cis acting element; Cytochrome P450 (CYP); Helix loop; Insulin; mRNA; Post transcriptional regulation

Indexed keywords

CELLS; INSULIN; LIVING SYSTEMS STUDIES; MOLECULAR STRUCTURE; PROTEINS;

CYTOPLASMIC PROTEINS; DIABETES; INSULIN DESTABILIZATION; PROTEIN FIXATION SITES;

BIOCHEMISTRY;

ANTISENSE OLIGODEOXYNUCLEOTIDE; CYTOCHROME P450 2B1; CYTOPLASM PROTEIN; INSULIN; MESSENGER RNA; RIBONUCLEASE T1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; MOLECULAR MECHANICS; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; PROTEIN STRUCTURE; REGULATORY SEQUENCE; RNA STABILITY;

APOGON BRACHYGRAMMUS;

EID: 19544384112     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041510     Document Type: Article

References (42)

1. Hall, R. K. and Granner, D. K. (1999) Insulin regulates expression of metabolic genes through divergent signaling pathways J. Basic Clin. Physiol. Pharmacol. 10, 119-133
2. De Waziers, I., Garlatti, M., Bouguet, J., Beaune, P. H. and Barouki, R. (1995) Insulin down-regulates cytochrome P450 2B and 2E expression at the post-transcriptional level in the rat hepatoma cell line. Mol. Pharmacol. 47, 474-479
3. Nelscn, D. R., Koymans, L., Kamataki, T. Stegeman, J. J., Feyereisen, R., Waxman, D. J., Waterman, M. R., Gotoh, O., Coon, M. J. and Estabrook, R. W. et at. (1996) P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6, 1-42
4. Reference deleted
5. Lieber, C. S. (1997) Cytochrome P-4502E1: its physiological and pathological role. Physiol. Rev. 77, 517-544
6. Koop, D. R. and Tierney, D. J. (1990) Multiple mechanisms in the regulation of ethanol-inducible cytochrome P450llE1. Bioessays 12, 429-435
7. Dong, Z. G., Hong, J. Y., Ma, Q. A., Li, D. C., Bullock, J., Gonzalez, F. J., Park, S. S., Gelboin, H. V. and Yang, C. S. (1988) Mechanism of induction of cytochrome P-450ac (P-450j) in chemically incuced and spontaneously diabetic rats. Arch. Biochem. Biophys. 263, 29-35
8. Song, B. J., Matsunaga, T., Hardwick, J. P., Park, S. S., Veech, R. L., Yang, C. S., Gelboin, H. V. and Gonzalez, F. J. (1987) Stabilization of cytochrome P450j messenger ribonucleic acid in the diabetic rat. Mol. Endocrinol. 1, 542-547
9. Yamazoe, Y., Murayama, N., Shimada, M., Yamauchi, K. and Kato, R. (1989) Cytochrome P450 in livers of diabetic rats: regulation by growth hormone and insulin. Arch. Biochem. Biophys. 268, 567-575
10. Wang, H. and Negishi M. (2003) Transcnptional regulation of cytochrome p450 2B genes by nuclear receptors. Curr. Drug. Metab. 4, 515-525
11. Woodcroft, K. J., Hafner, M. S. and Novak, R. F. (2002) Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression. Hepatology 35, 263-273
12. Day, D. A. and Tuite, M. F. (1998) Post-transcriptional gene regulatory mechanisms in eukaryotes: an overview. J. Endocrinol. 157, 361-371
13. Moncion, A., Truong, N. T., Garrone, A., Beaune, P., Barouki, R. and De Waziers, I. (2002) Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin. J. Biol. Chem. 277, 45904-45910
14. Pave-Preux, M., Aggerbeck, M., Veyssier, C., Bousquet-Lemercier, B., Hanoune, J. and Barouki, R. (1990) Hormona discrimination among transcription start sites of asparate aminotransferase. J. Biol. Chem. 265, 4444-4448
15. Guillouzo, A., Morel, F., Ratanasavanh, D., Chesné, C. and Guguen-Guillouzo, C. (1990) Long-term culture of fonctional hepatocytes. Toxicol in vitro 4, 415-427
16. Zandomeni, R., Mittleman, B., Bunick, D., Ackerman, S. and Weinmann, R. (1982) Mechanism of action of dichloro-β-o-ribofuranosylbenzimidazole: effect on in vitro transcription. Proc. Natl. Acad. Sci. U.S.A 79 3167-3170
17. Matzura, O. and Wennborg, A. (1996) RNAdraw: an integrated program for RNA secondary structure calculation and analysls under 32-bit Microsoft Windows. CABIOS Comput. Appl. Biosci. 12, 247-249
18. Peng, H. M. and Coon, M. J. (1998) Regulation of rabbit cytochrome P450 2E1 expression in HepG2 cells by insulin and thyroid hormocne. Mol. Pharmacol, 54, 740-747
19. Kawashima, J., Tsuruzoe, K. Motoshima, H., Shirakami, A., Sakai, K., Hirashima, Y., Toyonaga, T. and Araki, E. (2003) Insulin down-regulates resistin mRNA through the synthesis of protein(s) that could accelerate the degradation of resistin mRNA in 3T3-L1 adipocytes. Diabetologia 46, 231-240
20. Dreyfuss, G., Kim, V. N. and Kataoka, N. (2002) Messenger-RNA-binding proteins and the messages they carry. Nat. Rev. Mol. Cell. Biol. 3, 195-205
21. Raffalli-Mathieu, F., Geneste, O. and Lang, M. A. (1997) Characterization of two nuclear proteins that interact with cytochrome P-450 1A2 mRNA. Regulation of RNA binding and possible role in the expression of the Cyp1a2 gene. Eur. J. Bicchem. 245, 17-24
22. Silver, G. and Krsuter, K. S. (1988) Expression of cytochromes P-450c and P-450d mRNAs in cultured rat hepatocytes. 3-Methylcholanthrene induction is regulated primarily at the post-transcriptioia level. J. Biol. Chem. 263, 11802-11807
23. Ciolino, H. P. and Yeh, G. C. (1999) The steroid hormone dehydroepiandrosterone inhibits CYP1A1 expression in vitro by a pos:-transcriptional mechanism. J. Biol. Chem. 274, 35186-35190
24. Delaporte, E. and Renton, K. W. (1997) Cytochrome P4501A1 and cytochrome P4501A2 are downregulaled at both transcnptional and post-transcriptional levels by conditions resulting in interferon-α/β induction. Life Sci. 60, 787-796
25. Thuike-Gross, M., Hergenhahn, M., Tilloy-Ellul, A., Lang, M. and Bartsch, H. (1998) Pyrazole-inducible proteins in DBA/2 mouse liver bind with high affinity to the 3′-untranslated regions of the mRNAs of coumarin hydroxylase (CYP2A5) and c-jun. Biochem J. 331, 473-481
26. Tilloy-Ellul, A., Raffalli-Mathieu, F. and Lang, M. A. (1999) Analysis of RNA-protein interactions of mouse liver cytochrome P4502A5 mRNA. Biochem. J. 339, 695-703
27. Chen, C. Y. and Shyu, A. B. (1995) AU-rich elements: charactenzaticn and importance in mRNA degradation. Trends Biochem. Sci. 20, 465-470
28. Bernstein, P. L., Herrick, D. J., Prokipcak, R. D. and Ross, J (1992) Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant. Genes Dev. 6, 642-654
29. Schiavi, S C., Wellington, C. L., Shyu, A. B., Chen, C. Y., Greenberg, M. E. and Belasco, J. G. (1994) Multiple elements in the c-fos protein-coding region facilitate mRNA deadenylation and decay by a mechanism coupled to translation. J. Biol. Chem. 269, 3441-3443
30. Paste, M., Huez, G. and Kruys, V. (2003) Deadenylation of Interferon-β mRNA is mediated by both the AU-rich element in the 3′-untranslated region and an instability sequence in the coding region. Eur. J. Biochem. 270, 1590-1597
31. Yen, T. J., Gay, D. A., Pachter, J. S. and Cleveland, D. W. (1988) Autoregulated changes in stability of polyribosome-bound β-tubulin mRNAs are specified by the first 13 translated nucleotides. Mol Cell. Biol. 8, 1224-1235
32. Kebaara, B. Nazarenus, T., Taylor, R., Forch, A. and Atkin, A. L. (2003) The Upf-dependent decay of wild-type PPR1 mRNA depends on its 5′-UTR and first 92 ORF nucleotides. Nucleic Acids Res. 31, 3157-3165
33. Ito, J. and Jacobs-Lorena, M (2001) Functional mapping of destabilizing elements in the protein-coding region of the Drosophila fushi tarazu mRNA. J. Biol. Chem. 276, 23525-23530
34. Dandekar, T. and Hentze, M. W. (1995) Finding the hairpin in the haystack: searching for RNA motifs. Trends Genet. 11, 45-50
35. Williams, A. S. and Marzluff, W. F. (1995) The sequence of the stem and flanking sequences at the 3′ end of histone mRNA are critical determinants for the binding of the stem-loop binding protein. Nucleic Acids Res. 23, 654-662
36. White, S. A., Hoeger, M., Schweppe, J. J., Shillingford, A., Shipilov, V. and Zarutskie, J. (2004) Internal loop mutations in the ribosonnal protein L30 binding site of the yeast L30 RNA transcript. RNA 10, 369-377
37. Staton, J. M., Thomson, A. M. and Leedman, P. J. (2000) Hormonal regulation of mRNA stability and RNA-protein interactions in the pituitary. J. Mol. Endocrinol. 25, 17-34
38. Geneste, O., Raffalli, F. and Lang, M. A. (1996) Identification and characterization of a 44 kDa protein that binds specifically to the 3′-untranslated region of CYP2a5 mRNA: inducibility, subcellular distribution and possible role in mRNA stabilization. Biochem. J. 313, 1029-1037
39. Glisovic, T., Ben-David, Y., Lang, M. A. and Raffalli-Mathieu, F. (2003) Interplay between hnRNP A1 and a cis-acting element in the 3′ UTR of CYP2A5 mRNA is central for high expression of the gene. FEBS Lett. 535, 147-152
40. Yang, L., Yang, J., Huang, Y. and Liu, Z. R (2004) Phosphorylation of p68 RNA helicase regulates RNA bincing by the C-terminal domain of the protein. Biochem. Biophys. Res. Commun. 314, 622-630
41. Bomsztyk, K., Van Seuningen, I., Suzuki, H., Denisenko, O. and Ostrowski, J. (1997) Diverse molecular interactions of the hnRNP K protein. FEBS Lett. 403, 113-115
42. Ostrowski, J., Kawata, Y., Schullery, D. S., Denisenko, O. N., Higaki, Y., Abrass, C. K. and Bomsztyk, K. (2001) Insulin alters heterogeneous nuclear ribonucleoprotein K protein binding to DNA and RNA. Proc. Natl Acad. Sci. U.S.A 98, 9044-9049