Solution of a SAT problem on a photochemical DNA computer

Chemistry Letters

Volumn 34, Issue 3, 2005, Pages 378-379

  Ogasawara, Shinzi ^a   Fujimoto, Kenzo ^a,b  

^a JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYURIDINE DERIVATIVE; DNA; OLIGODEOXYNUCLEOTIDE DERIVATIVE;

ARTICLE; CALCULATION; COMPUTER; IRRADIATION; MATHEMATICAL MODEL; MEDICAL INFORMATION; MEDICAL INFORMATION SYSTEM; PHOTOCHEMISTRY;

EID: 19444387597     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2005.378     Document Type: Article

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13. (MERGE) Anchor-ODN (80 μM), all answer-ODNs (20 μM) and template-ODNs required for calculation (50 μM) were mixed in an aqueous solution containing 1.5 M NaCl, and 50 mM cacodylate buffer, pH 7.0 at room temperature (MARK) The solution was incubated at 95°C for 2 min, then cooled down to room temperature, and finally cooled to 0°C with continuous temperature decrease at a rate of 1°C per min, then irradiated with a transilluminator (366 nm) at 0°C for 3 h. (WASH) To the solution mixture, 7 M Urea was added to denature the duplex. (UNMARK) The solution was irradiated with a transilluminator (312 nm) at room temperature for 1.5 min.