A DNA computing readout operation based on structure-specific cleavage

Nature Biotechnology

Volumn 19, Issue 11, 2001, Pages 1053-1059

  Wang, Liman ^a   Hall, Jeff G ^b   Lu, Manchun ^a   Liu, Qinghua ^a   Smith, Lloyd M ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Third Wave Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL METHODS; ENZYMES; READOUT SYSTEMS;

ENZYMATIC CLEAVAGE;

DNA;

DNA; OLIGONUCLEOTIDE;

ACCURACY; ARTICLE; COMPUTER ANALYSIS; DNA CLEAVAGE; DNA HYBRIDIZATION; DNA SEQUENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DNA; HUMANS; MODELS, GENETIC; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDE PROBES; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SUBSTRATE SPECIFICITY;

EID: 0034764572     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1101-1053     Document Type: Article

References (32)

1. Molecular computation of solutions to combinatorial problems
2. DNA solution of hard computational problems
3. Making DNA add
4. DNA solution of the maximal clique problem
5. Design and self-assembly of two-dimensional DNA crystals
6. Solid phase DNA solution to the Hamiltonian Path problem
7. Solution to 3SAT by breadth first search
8. Molecular computation: RNA solutions to chess problems
9. Logical computation using algorithmic self-assembly of DNA triple-crossover molecules
10. DNA computing on,surfaces
11. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
12. Avoiding false positives with PCR
13. DNA amplification
14. The possibilities and limitations of nucleic acid amplification technology in diagnostic microbiology
15. PCR bias toward the wild-type k-ras and p53 sequences: Implications for PCR detection of mutations and cancer diagnosis
16. Polymorphism identification and quantitative detection of genomic DNA by invasive cleavage of oligonucleotide probes
17. Sensitive detection of DNA polymorphisms by the serial invasive signal amplification reaction
18. Demonstration of a word design strategy for DNA computing on surfaces
19. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer
20. Design and synthesis of new fluorogenic HIV protease substrates based on resonance energy-transfer
21. Thermodynamics and NMR of internal GT mismatches in DNA
22. Experimental and theoretical analysis of the invasive signal amplification reaction
23. A comparison of eubacterial and archaeal structure-specific 5′-exonuclease
24. Surface plasmon resonance imaging measurements of DNA hybridization adsorption and streptavidin/DNA multilayer formation at chemically modified gold surfaces
25. Direct genetic analysis by matrix-assisted laser desorption/ionization mass spectrometry
26. High level multiplex genotyping by MALDITOF mass spectrometry
27. Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation
28. Fluorescence detection in automated DNA-sequence analysis
29. DNA arrays for analysis of gene expression
30. Exploring the new world of the genome with DNA microarrays