Effect of structural modification on the inhibitory selectivity of rutaecarpine derivatives on human CYP1A1, CYP1A2, and CYP1B1

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 15, 2003, Pages 2535-2538

  Don, Ming Jaw ^a   Lewis, David F V ^b   Wang, Shu Yun ^a   Tsai, Mei Wen ^a   Ueng, Yune Fang ^a  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIMETHOXYRUTAECARPINE; 10 METHOXYRUTAECARPINE; 11 METHOXYRUTAECARPINE; ALKALOID; CYTOCHROME P 450 CYP1B1; CYTOCHROME P-450 CYP1B1; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; ENZYME INHIBITOR; ETHOXYRESORUFIN DEETHYLASE; PROTEIN INHIBITOR; RUTAECARPINE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BINDING SITE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; DRUG INHIBITION; DRUG STRUCTURE; HUMAN; HYDROGEN BOND; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

EID: 0037633665     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00469-4     Document Type: Article

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