Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 12, 2005, Pages 3910-3920

  Hazeldine, Stuart T ^a   Polin, Lisa ^a   Kushner, Juiwanna ^a   White, Kathryn ^a   Corbett, Thomas H ^a   Horwitz, Jerome P ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Analogs; Antitumor; SH80; XK469

Indexed keywords

2 [4 [(7 BROMO 2 QUINOXALINYL)OXY]PHENOXY]PROPIONIC ACID; 2 [4 [(7 CHLORO 2 QUINOXALINYL)OXY]PHENOXY]PROPIONIC ACID; PROPIONIC ACID DERIVATIVE; SH 80; UNCLASSIFIED DRUG; XK 469;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG TOLERABILITY; HUMAN; HUMAN CELL; REDUCTION; SUBSTITUTION REACTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; FLUORINE; HUMANS; METHYLATION; MICE; PROPIONIC ACIDS; QUINOXALINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

OXY;

EID: 19444362523     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.04.011     Document Type: Article

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