Improved asymmetric synthesis of dopamine D1 full agonist, dihydrexidine, employing chiral ligand-controlled asymmetric conjugate addition of aryllithium to a nitroalkene

Tetrahedron

Volumn 60, Issue 19, 2004, Pages 4237-4242

  Yamashita, Mitsuaki ^a   Yamada, Ken Ichi ^a   Tomioka, Kiyoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Agonist; Alkaloid; Asymmetric synthesis; Dopamine; Piperidine

Indexed keywords

1 DIMETHYLAMINO 2 (2 METHOXYPHENOXY) 1,2 DIPHENYLETHANE; 2 TRITYLOXYMETHYLPHENYLLITHIUM; DIHYDREXIDINE; DOPAMINE 1 RECEPTOR STIMULATING AGENT; LIGAND; LITHIUM DERIVATIVE; NITROALKANE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; ASYMMETRIC SYNTHESIS; CHIRALITY; CONJUGATION; CURTIUS REARRANGEMENT; CYCLIZATION; DRUG SYNTHESIS; PICTET SPENGLER REACTION; PRIORITY JOURNAL;

EID: 1942535888     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.03.039     Document Type: Article

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