메뉴 건너뛰기




Volumn 58, Issue 2, 2004, Pages 157-166

Automated Microscopy Identifies Estrogen Receptor Subdomains with Large-Scale Chromatin Structure Unfolding Activity

Author keywords

Automated microscopy; Chromatin; Estrogen receptor; High throughput screening; Steroid

Indexed keywords

ESTROGEN RECEPTOR;

EID: 1942534136     PISSN: 15524922     EISSN: None     Source Type: Journal    
DOI: 10.1002/cyto.a.10113     Document Type: Article
Times cited : (6)

References (41)
  • 1
    • 0036532026 scopus 로고    scopus 로고
    • Histone modifications in transcriptional regulation
    • Berger SL. Histone modifications in transcriptional regulation. Curr Opin Genet Dev 2002;12:142-148.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 142-148
    • Berger, S.L.1
  • 2
    • 0000247720 scopus 로고    scopus 로고
    • Promoter targeting of chromatin-modifying complexes
    • Hassan AH, Neely KE, Vignali M, et al. Promoter targeting of chromatin-modifying complexes. Front Biosci 2001;6:D1054-D1064.
    • (2001) Front Biosci , vol.6
    • Hassan, A.H.1    Neely, K.E.2    Vignali, M.3
  • 3
    • 0035371920 scopus 로고    scopus 로고
    • Visualizing chromosome dynamics with GFP
    • Belmont AS. Visualizing chromosome dynamics with GFP. Trends Cell Biol 2001;11:250-257.
    • (2001) Trends Cell Biol , vol.11 , pp. 250-257
    • Belmont, A.S.1
  • 4
    • 0032608360 scopus 로고    scopus 로고
    • Visualization of large-scale chromatin structure and dynamics using the lac operator/lac repressor reporter system
    • Belmont AS, Li G, Sudlow G, Robinett C. Visualization of large-scale chromatin structure and dynamics using the lac operator/lac repressor reporter system. Methods Cell Biol 1999;58:203-222.
    • (1999) Methods Cell Biol , vol.58 , pp. 203-222
    • Belmont, A.S.1    Li, G.2    Sudlow, G.3    Robinett, C.4
  • 5
    • 0033612538 scopus 로고    scopus 로고
    • Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain
    • Tumbar T, Sudlow G, Belmont AS. Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain. J Cell Biol 1999;145:1341-1354.
    • (1999) J Cell Biol , vol.145 , pp. 1341-1354
    • Tumbar, T.1    Sudlow, G.2    Belmont, A.S.3
  • 6
    • 0035833262 scopus 로고    scopus 로고
    • Large-scale chromatin decondensation and recondensation regulated by transcription from a natural promoter
    • Muller WG, Walker D, Hager GL, McNally JG. Large-scale chromatin decondensation and recondensation regulated by transcription from a natural promoter. J Cell Biol 2001;154:33-48.
    • (2001) J Cell Biol , vol.154 , pp. 33-48
    • Muller, W.G.1    Walker, D.2    Hager, G.L.3    McNally, J.G.4
  • 7
    • 0035842893 scopus 로고    scopus 로고
    • BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations
    • Ye Q, Hu YF, Zhong H, et al. BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J Cell Biol 2001;155:911-921.
    • (2001) J Cell Biol , vol.155 , pp. 911-921
    • Ye, Q.1    Hu, Y.F.2    Zhong, H.3
  • 8
    • 0036233630 scopus 로고    scopus 로고
    • Alteration of large-scale chromatin structure by estrogen receptor
    • Nye AC, Rajendran RR, Stenoien DL, et al. Alteration of large-scale chromatin structure by estrogen receptor. Mol Cell Biol 2002;22: 3437-3449.
    • (2002) Mol Cell Biol , vol.22 , pp. 3437-3449
    • Nye, A.C.1    Rajendran, R.R.2    Stenoien, D.L.3
  • 9
    • 0034464112 scopus 로고    scopus 로고
    • Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1
    • Stenoien DL, Mancini MG, Patel K, et al. Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1. Mol Endocrinol 2000;14:518-534.
    • (2000) Mol Endocrinol , vol.14 , pp. 518-534
    • Stenoien, D.L.1    Mancini, M.G.2    Patel, K.3
  • 10
    • 0035823254 scopus 로고    scopus 로고
    • Real-time molecular and cellular analysis: The new frontier of drug discovery
    • Taylor DL, Woo ES, Giuliano KA. Real-time molecular and cellular analysis: the new frontier of drug discovery. Curr Opin Biotechnol 2001;12:75-81.
    • (2001) Curr Opin Biotechnol , vol.12 , pp. 75-81
    • Taylor, D.L.1    Woo, E.S.2    Giuliano, K.A.3
  • 11
    • 0345012069 scopus 로고    scopus 로고
    • Clinical applications of laser scanning cytometry
    • Tarnok A, Gerstner AO. Clinical applications of laser scanning cytometry. Cytometry 2002;50:133-143.
    • (2002) Cytometry , vol.50 , pp. 133-143
    • Tarnok, A.1    Gerstner, A.O.2
  • 12
    • 0033970143 scopus 로고    scopus 로고
    • Detection and analysis of cancer cells in blood and bone marrow using a rare event imaging system
    • Kraeft SK, Sutherland R, Gravelin L, et al. Detection and analysis of cancer cells in blood and bone marrow using a rare event imaging system. Clin Cancer Res 2000;6:434-442.
    • (2000) Clin Cancer Res , vol.6 , pp. 434-442
    • Kraeft, S.K.1    Sutherland, R.2    Gravelin, L.3
  • 13
    • 0032425161 scopus 로고    scopus 로고
    • An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (M-FISH)
    • Eils R, Uhrig S, Saracoglu K, et al. An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (M-FISH). Cytogenet Cell Genet 1998;82: 160-171.
    • (1998) Cytogenet Cell Genet , vol.82 , pp. 160-171
    • Eils, R.1    Uhrig, S.2    Saracoglu, K.3
  • 14
    • 0030984704 scopus 로고    scopus 로고
    • FISH and chips: Automation of fluorescent dot counting in interphase cell nuclei
    • Netten H, Young IT, van Vliet LJ, et al. FISH and chips: automation of fluorescent dot counting in interphase cell nuclei. Cytometry 1997; 28:1-10.
    • (1997) Cytometry , vol.28 , pp. 1-10
    • Netten, H.1    Young, I.T.2    Van Vliet, L.J.3
  • 15
    • 0033989056 scopus 로고    scopus 로고
    • Laser scanning cytometry for comet assay analysis
    • Petersen AB, Gniadecki R, Wulf HC. Laser scanning cytometry for comet assay analysis. Cytometry 2000;39:10-15.
    • (2000) Cytometry , vol.39 , pp. 10-15
    • Petersen, A.B.1    Gniadecki, R.2    Wulf, H.C.3
  • 16
    • 0034564140 scopus 로고    scopus 로고
    • Towards a systematics for protein subcelluar location: Quantitative description of protein localization patterns and automated analysis of fluorescence microscope images
    • Murphy RF, Boland MV, Velliste M. Towards a systematics for protein subcelluar location: quantitative description of protein localization patterns and automated analysis of fluorescence microscope images. Proc Int Conf Intell Syst Mol Biol 2000;8:251-259.
    • (2000) Proc Int Conf Intell Syst Mol Biol , vol.8 , pp. 251-259
    • Murphy, R.F.1    Boland, M.V.2    Velliste, M.3
  • 17
    • 0036852721 scopus 로고    scopus 로고
    • Automated subcellular localization and quantification of protein expression in tissue microarrays
    • Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med 2002;8:1323-1328.
    • (2002) Nat Med , vol.8 , pp. 1323-1328
    • Camp, R.L.1    Chung, G.G.2    Rimm, D.L.3
  • 19
    • 0027424372 scopus 로고
    • Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast
    • Wrenn CK, Katzenellenbogen BS. Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast. J Biol Chem 1993;268:24089-24098.
    • (1993) J Biol Chem , vol.268 , pp. 24089-24098
    • Wrenn, C.K.1    Katzenellenbogen, B.S.2
  • 20
    • 0032498902 scopus 로고    scopus 로고
    • Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: Precise choreography of condensation/decondensation and nuclear positioning
    • Li G, Sudlow G, Belmont AS. Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: precise choreography of condensation/decondensation and nuclear positioning. J Cell Biol 1998;140:975-989.
    • (1998) J Cell Biol , vol.140 , pp. 975-989
    • Li, G.1    Sudlow, G.2    Belmont, A.S.3
  • 21
    • 0030461543 scopus 로고    scopus 로고
    • In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition
    • Robinett CC, Straight A, Li G, et al. In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition. J Cell Biol 1996;135(pt 2):1685-1700.
    • (1996) J Cell Biol , vol.135 , Issue.PART 2 , pp. 1685-1700
    • Robinett, C.C.1    Straight, A.2    Li, G.3
  • 22
    • 0000251397 scopus 로고
    • Das heterochromatin der moose
    • Heitz E. Das heterochromatin der moose. Jahresbehr Wiss Botanik 1928;69:762-818.
    • (1928) Jahresbehr Wiss Botanik , vol.69 , pp. 762-818
    • Heitz, E.1
  • 23
    • 0030445855 scopus 로고    scopus 로고
    • Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein
    • Weis KE, Ekena K, Thomas JA, et al. Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein. Mol Endocrinol 1996;10:1388-1398.
    • (1996) Mol Endocrinol , vol.10 , pp. 1388-1398
    • Weis, K.E.1    Ekena, K.2    Thomas, J.A.3
  • 24
    • 0033646066 scopus 로고    scopus 로고
    • Function of N-terminal transactivation domain of the estrogen receptor requires a potential alpha-helical structure and is negatively regulated by the A domain
    • Metivier R, Petit FG, Valotaire Y, Pakdel F. Function of N-terminal transactivation domain of the estrogen receptor requires a potential alpha-helical structure and is negatively regulated by the A domain. Mol Endocrinol 2000;14:1849-1871.
    • (2000) Mol Endocrinol , vol.14 , pp. 1849-1871
    • Metivier, R.1    Petit, F.G.2    Valotaire, Y.3    Pakdel, F.4
  • 25
    • 0028305554 scopus 로고
    • A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast
    • Pierrat B, Heery DM, Chambon P, Losson R. A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast. Gene 1994;143:193-200.
    • (1994) Gene , vol.143 , pp. 193-200
    • Pierrat, B.1    Heery, D.M.2    Chambon, P.3    Losson, R.4
  • 26
    • 0030667676 scopus 로고    scopus 로고
    • Molecular basis of agonism and antagonism in the oestrogen receptor
    • Brzozowski AM, Pike AC, Dauter Z et al. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 1997;389:753-758.
    • (1997) Nature , vol.389 , pp. 753-758
    • Brzozowski, A.M.1    Pike, A.C.2    Dauter, Z.3
  • 27
    • 0032568527 scopus 로고    scopus 로고
    • Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains
    • Tanenbaum DM, Wang Y, Williams SP, Sigler PB. Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains. Proc Natl Acad Sci USA 1998;95:5998-6003.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5998-6003
    • Tanenbaum, D.M.1    Wang, Y.2    Williams, S.P.3    Sigler, P.B.4
  • 28
    • 0033054115 scopus 로고    scopus 로고
    • The structure of the nuclear hormone receptors
    • Kumar R, Thompson EB. The structure of the nuclear hormone receptors. Steroids 1999;64:310-319.
    • (1999) Steroids , vol.64 , pp. 310-319
    • Kumar, R.1    Thompson, E.B.2
  • 29
    • 0027402497 scopus 로고
    • Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activator
    • Regier JL, Shen F, Triezenberg SJ. Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activator. Proc Natl Acad Sci USA 1993;90:883-887.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 883-887
    • Regier, J.L.1    Shen, F.2    Triezenberg, S.J.3
  • 30
    • 0024276524 scopus 로고
    • Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif
    • Courey AJ, Tjian R. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 1988;55:887-898.
    • (1988) Cell , vol.55 , pp. 887-898
    • Courey, A.J.1    Tjian, R.2
  • 31
    • 0028840090 scopus 로고
    • The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids
    • Drysdale CM, Duenas E, Jackson BM et al. The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids. Mol Cell Biol 1995;15:1220-1233.
    • (1995) Mol Cell Biol , vol.15 , pp. 1220-1233
    • Drysdale, C.M.1    Duenas, E.2    Jackson, B.M.3
  • 32
    • 0027512191 scopus 로고
    • Conservation of transcriptional activation functions of the NF-kappa B p50 and p65 subunits in mammalian cells and Saccharomyces cerevisiae
    • Moore PA, Ruben SM, Rosen CA. Conservation of transcriptional activation functions of the NF-kappa B p50 and p65 subunits in mammalian cells and Saccharomyces cerevisiae. Mol Cell Biol 1993; 13:1666-1674.
    • (1993) Mol Cell Biol , vol.13 , pp. 1666-1674
    • Moore, P.A.1    Ruben, S.M.2    Rosen, C.A.3
  • 33
    • 0034032022 scopus 로고    scopus 로고
    • Estrogen receptor interaction with co-activators and co-repressors
    • Klinge CM. Estrogen receptor interaction with co-activators and co-repressors. Steroids 2000;65:227-251.
    • (2000) Steroids , vol.65 , pp. 227-251
    • Klinge, C.M.1
  • 34
    • 0028170036 scopus 로고
    • Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor
    • Jacq X, Brou C, Lutz Y, et al. Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell 1994;79:107-117.
    • (1994) Cell , vol.79 , pp. 107-117
    • Jacq, X.1    Brou, C.2    Lutz, Y.3
  • 35
    • 0034680931 scopus 로고    scopus 로고
    • Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA
    • Delage-Mourroux R, Martini PG, Choi I, et al. Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA. J Biol Chem 2000;275:35848-35856.
    • (2000) J Biol Chem , vol.275 , pp. 35848-35856
    • Delage-Mourroux, R.1    Martini, P.G.2    Choi, I.3
  • 36
    • 0036020499 scopus 로고    scopus 로고
    • Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists
    • Huang HJ, Norris JD, McDonnell DP. Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists. Mol Endocrinol 2002;16:1778-1792.
    • (2002) Mol Endocrinol , vol.16 , pp. 1778-1792
    • Huang, H.J.1    Norris, J.D.2    McDonnell, D.P.3
  • 37
    • 0026553759 scopus 로고
    • Comparison of the 90-kilodalton heat shock protein interaction with in vitro translated glucocorticoid and estrogen receptors
    • Schlatter LK, Howard KJ, Parker MG, Distelhorst CW. Comparison of the 90-kilodalton heat shock protein interaction with in vitro translated glucocorticoid and estrogen receptors. Mol Endocrinol 1992;6: 132-140.
    • (1992) Mol Endocrinol , vol.6 , pp. 132-140
    • Schlatter, L.K.1    Howard, K.J.2    Parker, M.G.3    Distelhorst, C.W.4
  • 38
    • 0025251798 scopus 로고
    • Several regions of human estrogen receptor are involved in the formation of receptor-heat shock protein 90 complexes
    • Chambraud B, Berry M, Redeuilh G, et al. Several regions of human estrogen receptor are involved in the formation of receptor-heat shock protein 90 complexes. J Biol Chem 1990;265:20686-20691.
    • (1990) J Biol Chem , vol.265 , pp. 20686-20691
    • Chambraud, B.1    Berry, M.2    Redeuilh, G.3
  • 39
    • 0035804228 scopus 로고    scopus 로고
    • Role of direct interaction in BRCA1 inhibition of estrogen receptor activity
    • Fan S, Ma YX, Wang C, et al. Role of direct interaction in BRCA1 inhibition of estrogen receptor activity. Oncogene 2001;20:77-87.
    • (2001) Oncogene , vol.20 , pp. 77-87
    • Fan, S.1    Ma, Y.X.2    Wang, C.3
  • 40
    • 0034700166 scopus 로고    scopus 로고
    • Small molecule developmental screens reveal the logic and timing of vertebrate development
    • Peterson RT, Link BA, Dowling JE, Schreiber SL. Small molecule developmental screens reveal the logic and timing of vertebrate development. Proc Natl Acad Sci USA 2000;97:12965-12969.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12965-12969
    • Peterson, R.T.1    Link, B.A.2    Dowling, J.E.3    Schreiber, S.L.4
  • 41
    • 0033615357 scopus 로고    scopus 로고
    • Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
    • Mayer TU, Kapoor TM, Haggarty SJ, et al. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science 1999;286:971-974.
    • (1999) Science , vol.286 , pp. 971-974
    • Mayer, T.U.1    Kapoor, T.M.2    Haggarty, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.